Results 1 to 10 of about 88,724 (251)

Neonatal Deletion of Hand1 and Hand2 within Murine Cardiac Conduction System Reveals a Novel Role for HAND2 in Rhythm Homeostasis [PDF]

Journal of Cardiovascular Development and Disease, 2022
The cardiac conduction system, a network of specialized cells, is required for the functioning of the heart. The basic helix loop helix factors Hand1 and Hand2 are required for cardiac morphogenesis and have been implicated in cardiac conduction system ...
Rajani M. George, Shuai Guo, Beth A. Firulli, Michael Rubart, Anthony B. Firulli   +4 more
doaj   +2 more sources

Dbh + catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart [PDF]

Nature Communications, 2023
The heterogeneity of functional cardiomyocytes arises during heart development, which is essential to the complex and highly coordinated cardiac physiological function.
Tianyi Sun, Alexander Grassam-Rowe, Zhaoli Pu, Yangpeng Li, Huiying Ren, Yanru An, Xinyu Guo, Wei Hu, Ying Liu, Yuqing Zheng, Zhu Liu, Kun Kou, Xianhong Ou, Tangting Chen, Xuehui Fan, Yangyang Liu, Shu Tu, Yu He, Yue Ren, Ao Chen, Zhouchun Shang, Zhidao Xia, Lucile Miquerol, Nicola Smart, Henggui Zhang, Xiaoqiu Tan, Weinian Shou, Ming Lei   +27 more
doaj   +2 more sources

Sudden Unexpected Infant and Perinatal Death: Pathological Findings of the Cardiac Conduction System [PDF]

Diagnostics
Objective: Sudden infant death syndrome (SIDS), sudden neonatal unexpected death (SNUD), and sudden intrauterine unexpected death (SIUD) are major unsolved, shocking forms of death that occur frequently and without warning.
Giulia Ottaviani, Patrizia Leonardi, Massimo Del Fabbro, Simone G. Ramos   +3 more
doaj   +2 more sources

Cardiac Resynchronisation with Conduction System Pacing

Arrhythmia & Electrophysiology Review, 2023
To date, biventricular pacing (BiVP) has been the standard pacing modality for cardiac resynchronisation therapy. However, it is non-physiological, with the activation spreading between the left ventricular epicardium and right ventricular endocardium ...
Fatima M Ezzeddine, Isaac G Leon, Yong-Mei Cha   +2 more
doaj   +4 more sources

Pleural and pericardial effusions with cardiac conduction system and myocardial involvement: A rare presentation of sarcoidosis [PDF]

Radiology Case Reports, 2022
Sarcoidosis is a granulomatous immune disorder that can infiltrate many organ systems. When the cardiac system is involved, the myocardium and conduction system are frequently affected. We report the case of a patient presenting with complete heart block
Christine Vincent, BA, Oleg Reznik, MD, Joel Raju, MD, Alina Popa, MD   +3 more
doaj   +2 more sources

Transcriptional regulation of the postnatal cardiac conduction system heterogeneity [PDF]

Nature Communications
The cardiac conduction system (CCS) is a network of specialized cardiomyocytes that coordinates electrical impulse generation and propagation for synchronized heart contractions.
Yena Oh, Rimshah Abid, Saif Dababneh, Marwan Bakr, Termeh Aslani, David P. Cook, Barbara C. Vanderhyden, Jin G. Park, Nikhil V. Munshi, Chi-Chung Hui, Kyoung-Han Kim   +10 more
doaj   +2 more sources

Regulation of Cardiac Conduction and Arrhythmias by Ankyrin/Spectrin-Based Macromolecular Complexes

Journal of Cardiovascular Development and Disease, 2021
The cardiac conduction system is an extended network of excitable tissue tasked with generation and propagation of electrical impulses to signal coordinated contraction of the heart.
Drew Nassal, Jane Yu, Dennison Min, Cemantha Lane, Rebecca Shaheen, Daniel Gratz, Thomas J. Hund   +6 more
doaj   +1 more source

Incidence of carditis and predictors of pacemaker implantation in patients hospitalized with Lyme disease

PLoS ONE, 2021
Background Lyme carditis, defined as direct infection of cardiac tissue by Borrelia bacteria, affects up to 10% of patients with Lyme disease. The most frequently reported clinical manifestation of Lyme carditis is cardiac conduction system disease.
Uwajachukwumma A. Uzomah, Guy Rozen, Seyed Mohammadreza Hosseini, Ayman Shaqdan, Pablo A. Ledesma, Xuejing Yu, Pegah Khaloo, Jennifer Galvin, Leon M. Ptaszek, Jeremy N. Ruskin   +9 more
doaj   +2 more sources

Conduction System Pacing for Cardiac Resynchronization Therapy

Journal of Cardiovascular Development and Disease, 2023
Cardiac resynchronization therapy (CRT) via biventricular pacing (BiVP-CRT) is considered a mainstay treatment for symptomatic heart failure patients with reduced ejection fraction and wide QRS. However, up to one-third of patients receiving BiVP-CRT are
Óscar Cano, Javier Navarrete-Navarro, Pablo Jover, Joaquín Osca, Maite Izquierdo, Josep Navarro, Hebert D. Ayala, Luis Martínez-Dolz   +7 more
doaj   +1 more source

Left Bundle Branch Pacing in Transthyretin Cardiac Amyloidosis and Alternating Bundle Branch Block

JACC: Case Reports, 2020
Progressive conduction system disease affects patients with transthyretin cardiac amyloidosis, often requiring permanent pacing as the His-Purkinje system is affected. We present a case of left bundle branch pacing in a patient with transthyretin cardiac
Taha Ahmed, MD, Samra Haroon Lodhi, MBBS, Hassan Lak, MD, Jae Lee, MD, Mazen Hanna, MD, Roy Chung, MD   +5 more
doaj   +1 more source