Results 41 to 50 of about 141,036 (291)
Dynamics of conduction blocks in a model of paced cardiac tissue [PDF]
, 2005 We study numerically the dynamics of conduction blocks using a detailed electrophysiological model. We find that this dynamics depends critically on the size of the paced region.
C. H. Luo +7 more
core +1 more source
Discretization-dependent model for weakly connected excitable media [PDF]
, 2018 Pattern formation has been widely observed in extended chemical and biological processes. Although the biochemical systems are highly heterogeneous, homogenized continuum approaches formed by partial differential equations have been employed frequently ...
Alonso Muñoz, Sergio +2 more
core +2 more sources
Cardiac conduction system anomalies and sudden cardiac death: insights from murine models
Frontiers in Physiology, 2012 The cardiac conduction system (CCS) is a series of specialized tissues in the heart responsible for the initiation and co-ordination of the heartbeat. Alterations in the CCS, especially the His-Purkinje system, have been identified as an important player
Amelia Eva Aranega +2 more
doaj +1 more source
CaMKII-dependent regulation of cardiac Na(+) homeostasis. [PDF]
, 2014 Na(+) homeostasis is a key regulator of cardiac excitation and contraction. The cardiac voltage-gated Na(+) channel, NaV1.5, critically controls cell excitability, and altered channel gating has been implicated in both inherited and acquired arrhythmias.
Grandi, Eleonora, Herren, Anthony W
core +2 more sources
An Appreciation of Anatomy in the Molecular World
Journal of Cardiovascular Development and Disease, 2020 Robert H. Anderson is one of the most important and accomplished cardiac anatomists of the last decades, having made major contributions to our understanding of the anatomy of normal hearts and the pathologies of acquired and congenital heart diseases ...
Bjarke Jensen +2 more
doaj +1 more source
Nonlinear physics of electrical wave propagation in the heart: a review [PDF]
, 2016 The beating of the heart is a synchronized contraction of muscle cells (myocytes) that are triggered by a periodic sequence of electrical waves (action potentials) originating in the sino-atrial node and propagating over the atria and the ventricles ...
Alonso Muñoz, Sergio +2 more
core +2 more sources
Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12 [PDF]
, 2019 Cardiomyocyte-restricted overexpression of FK506-binding protein 12 transgenic (αMyHC-FKBP12) mice develop spontaneous atrial fibrillation (AF). The aim of the present study is to explore the mechanisms underlying the occurrence of AF in αMyHC-FKBP12 ...
Ai, Tomohiko +14 more
core +1 more source
Zebrafish Models in Therapeutic Research of Cardiac Conduction Disease
Frontiers in Cell and Developmental Biology, 2021 Malfunction in the cardiac conduction system (CCS) due to congenital anomalies or diseases can cause cardiac conduction disease (CCD), which results in disturbances in cardiac rhythm, leading to syncope and even sudden cardiac death.
Rui Gao, Jie Ren
doaj +1 more source
Development of the Cardiac Conduction System [PDF]
Circulation Research, 1998 In the formed heart, it is convention to distinguish working myocardium (the primary function of which is contraction) from the conduction system (the primary function of which is the generation and conduction of the electrical impulse). The conduction system comprises separate components with distinct functions.
A F, Moorman +3 more
openaire +2 more sources
Numerical simulation of electrocardiograms for full cardiac cycles in healthy and pathological conditions [PDF]
, 2015 This work is dedicated to the simulation of full cycles of the electrical activity of the heart and the corresponding body surface potential. The model is based on a realistic torso and heart anatomy, including ventricles and atria.
Bayés de Luna +61 more
core +5 more sources