Cardiac conduction system- A detailed study in 46 cases of sudden death
Background: Atherosclerotic coronary artery disease is the modern pandemic and is said to be responsible for a major chunk of sudden cardiac deaths. However, in few cases; especially among the young, conduction system abnormalities were found to be the ...
LM Ilias +5 more
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Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12 [PDF]
Cardiomyocyte-restricted overexpression of FK506-binding protein 12 transgenic (αMyHC-FKBP12) mice develop spontaneous atrial fibrillation (AF). The aim of the present study is to explore the mechanisms underlying the occurrence of AF in αMyHC-FKBP12 ...
Ai, Tomohiko +14 more
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Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system. [PDF]
Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery.
Gimzewski, James K +7 more
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A concise review on the anatomy of the atrioventricular node in mammals [PDF]
Cardiac conduction system enables the heart to pulsate continuously by producing electric impulse and conducting it. As the anatomical information about cardiac conduction system in human being and other mammals needed in various fields of sciences, such
Abolghassem Nabipour
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CaMKII-dependent regulation of cardiac Na(+) homeostasis. [PDF]
Na(+) homeostasis is a key regulator of cardiac excitation and contraction. The cardiac voltage-gated Na(+) channel, NaV1.5, critically controls cell excitability, and altered channel gating has been implicated in both inherited and acquired arrhythmias.
Grandi, Eleonora, Herren, Anthony W
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Nonlinear physics of electrical wave propagation in the heart: a review [PDF]
The beating of the heart is a synchronized contraction of muscle cells (myocytes) that are triggered by a periodic sequence of electrical waves (action potentials) originating in the sino-atrial node and propagating over the atria and the ventricles ...
Alonso Muñoz, Sergio +2 more
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Asymptotic properties of mathematical models of excitability [PDF]
We analyse small parameters in selected models of biological excitability, including Hodgkin-Huxley (1952) model of nerve axon, Noble (1962) model of heart Purkinje fibres, and Courtemanche et al. (1998) model of human atrial cells.
Biktashev, V. N. +3 more
core +2 more sources
Cardiac conduction system anomalies and sudden cardiac death: insights from murine models
The cardiac conduction system (CCS) is a series of specialized tissues in the heart responsible for the initiation and co-ordination of the heartbeat. Alterations in the CCS, especially the His-Purkinje system, have been identified as an important player
Amelia Eva Aranega +2 more
doaj +1 more source
An Appreciation of Anatomy in the Molecular World
Robert H. Anderson is one of the most important and accomplished cardiac anatomists of the last decades, having made major contributions to our understanding of the anatomy of normal hearts and the pathologies of acquired and congenital heart diseases ...
Bjarke Jensen +2 more
doaj +1 more source
Dynamics of conduction blocks in a model of paced cardiac tissue [PDF]
We study numerically the dynamics of conduction blocks using a detailed electrophysiological model. We find that this dynamics depends critically on the size of the paced region.
C. H. Luo +7 more
core +1 more source

