Results 31 to 40 of about 139,869 (296)

Cardiac conduction system- A detailed study in 46 cases of sudden death

open access: yesJournal of Pathology of Nepal, 2015
Background: Atherosclerotic coronary artery disease is the modern pandemic and is said to be responsible for a major chunk of sudden cardiac deaths. However, in few cases; especially among the young, conduction system abnormalities were found to be the ...
LM Ilias   +5 more
doaj   +1 more source

Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12 [PDF]

open access: yes, 2019
Cardiomyocyte-restricted overexpression of FK506-binding protein 12 transgenic (αMyHC-FKBP12) mice develop spontaneous atrial fibrillation (AF). The aim of the present study is to explore the mechanisms underlying the occurrence of AF in αMyHC-FKBP12 ...
Ai, Tomohiko   +14 more
core   +1 more source

Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system. [PDF]

open access: yes, 2017
Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery.
Gimzewski, James K   +7 more
core   +2 more sources

A concise review on the anatomy of the atrioventricular node in mammals [PDF]

open access: yesThe Iranian Journal of Veterinary Science and Technology, 2009
Cardiac conduction system enables the heart to pulsate continuously by producing electric impulse and conducting it. As the anatomical information about cardiac conduction system in human being and other mammals needed in various fields of sciences, such
Abolghassem Nabipour
doaj   +1 more source

CaMKII-dependent regulation of cardiac Na(+) homeostasis. [PDF]

open access: yes, 2014
Na(+) homeostasis is a key regulator of cardiac excitation and contraction. The cardiac voltage-gated Na(+) channel, NaV1.5, critically controls cell excitability, and altered channel gating has been implicated in both inherited and acquired arrhythmias.
Grandi, Eleonora, Herren, Anthony W
core   +2 more sources

Nonlinear physics of electrical wave propagation in the heart: a review [PDF]

open access: yes, 2016
The beating of the heart is a synchronized contraction of muscle cells (myocytes) that are triggered by a periodic sequence of electrical waves (action potentials) originating in the sino-atrial node and propagating over the atria and the ventricles ...
Alonso Muñoz, Sergio   +2 more
core   +2 more sources

Asymptotic properties of mathematical models of excitability [PDF]

open access: yes, 2005
We analyse small parameters in selected models of biological excitability, including Hodgkin-Huxley (1952) model of nerve axon, Noble (1962) model of heart Purkinje fibres, and Courtemanche et al. (1998) model of human atrial cells.
Biktashev, V. N.   +3 more
core   +2 more sources

Cardiac conduction system anomalies and sudden cardiac death: insights from murine models

open access: yesFrontiers in Physiology, 2012
The cardiac conduction system (CCS) is a series of specialized tissues in the heart responsible for the initiation and co-ordination of the heartbeat. Alterations in the CCS, especially the His-Purkinje system, have been identified as an important player
Amelia Eva Aranega   +2 more
doaj   +1 more source

An Appreciation of Anatomy in the Molecular World

open access: yesJournal of Cardiovascular Development and Disease, 2020
Robert H. Anderson is one of the most important and accomplished cardiac anatomists of the last decades, having made major contributions to our understanding of the anatomy of normal hearts and the pathologies of acquired and congenital heart diseases ...
Bjarke Jensen   +2 more
doaj   +1 more source

Dynamics of conduction blocks in a model of paced cardiac tissue [PDF]

open access: yes, 2005
We study numerically the dynamics of conduction blocks using a detailed electrophysiological model. We find that this dynamics depends critically on the size of the paced region.
C. H. Luo   +7 more
core   +1 more source

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