Incorporating Inductances in Tissue-Scale Models of Cardiac Electrophysiology [PDF]
, 2017 In standard models of cardiac electrophysiology, including the bidomain and monodomain models, local perturbations can propagate at infinite speed.
Balay S. +17 more
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A 21st century view of the anatomy of the cardiac conduction system
Translational Research in Anatomy, 2022 Introduction: Since the discovery of the major components of the cardiac conduction system (CCS) by the early 20th century we have seen many technological advancements that have allowed immense insight into the CCS tissues. In this review we will discuss
Areej Arshad, Andrew J. Atkinson
doaj +1 more source
Premature MicroRNA-1 Expression Causes Hypoplasia of the Cardiac Ventricular Conduction System. [PDF]
, 2019 Mammalian cardiac Purkinje fibers (PFs) are specified from ventricular trabecular myocardium during mid-gestation and undergo limited proliferation before assuming their final form.
Evangelista, Melissa +5 more
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Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12 [PDF]
, 2019 Cardiomyocyte-restricted overexpression of FK506-binding protein 12 transgenic (αMyHC-FKBP12) mice develop spontaneous atrial fibrillation (AF). The aim of the present study is to explore the mechanisms underlying the occurrence of AF in αMyHC-FKBP12 ...
Ai, Tomohiko +14 more
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Modeling the Heart as a Communication System [PDF]
, 2014 Electrical communication between cardiomyocytes can be perturbed during arrhythmia, but these perturbations are not captured by conventional electrocardiographic metrics.
Aguilar-Rodríguez, José +7 more
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Bidirectional ventricular tachycardia in cardiac sarcoidosis. [PDF]
, 2016 A 73-year-old man with history of pulmonary sarcoidosis was found to have runs of non-sustained bidirectional ventricular tachycardia (BVT) with two different QRS morphologies on a Holter monitor.
Benjamin, Mina M +4 more
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Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system. [PDF]
, 2017 Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery.
Gimzewski, James K +7 more
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Dynamics of conduction blocks in a model of paced cardiac tissue [PDF]
, 2005 We study numerically the dynamics of conduction blocks using a detailed electrophysiological model. We find that this dynamics depends critically on the size of the paced region.
C. H. Luo +7 more
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CaMKII-dependent regulation of cardiac Na(+) homeostasis. [PDF]
, 2014 Na(+) homeostasis is a key regulator of cardiac excitation and contraction. The cardiac voltage-gated Na(+) channel, NaV1.5, critically controls cell excitability, and altered channel gating has been implicated in both inherited and acquired arrhythmias.
Grandi, Eleonora, Herren, Anthony W
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Asymptotic properties of mathematical models of excitability [PDF]
, 2005 We analyse small parameters in selected models of biological excitability, including Hodgkin-Huxley (1952) model of nerve axon, Noble (1962) model of heart Purkinje fibres, and Courtemanche et al. (1998) model of human atrial cells.
Biktashev, V. N. +3 more
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