Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis [PDF]
, 2016 Objective: First-degree atrioventricular block is frequently encountered in clinical practice and is generally considered a benign process. However, there is emerging evidence that prolonged PR interval may be associated with adverse outcomes. This study
Barker, Diane +11 more
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Loss of muscleblind-like 1 results in cardiac pathology and persistence of embryonic splice isoforms. [PDF]
, 2015 Cardiac dysfunction is a prominent cause of mortality in myotonic dystrophy I (DM1), a disease where expanded CUG repeats bind and disable the muscleblind-like family of splice regulators.
Choi, Jongkyu +8 more
core
Possible predicative role of electrical risk score on transcatheter aortic valve replacement outcomes in older patients. preliminary data [PDF]
, 2018 Background:Transcatheter aortic valve replacement (TAVR) is an effective procedure capable to change the natural history of the degenerative aortic valve stenosis.
DI IORIO, Claudia +9 more
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Early Disseminated Lyme Disease with Carditis Complicated by Posttreatment Lyme Disease Syndrome
Case Reports in Infectious Diseases, 2017 Lyme disease is an infectious disease caused by the bacterium Borrelia burgdorferi. When untreated, infection may spread to the heart, nervous system, and joints.
Cheryl Novak +2 more
doaj +1 more source
Syncope and paroxysmal atrioventricular block
Journal of Arrhythmia, 2017 Current literature reveals three types of paroxysmal atrioventricular block (AVB) that can cause syncope:Intrinsic paroxysmal atrioventricular block is due to an intrinsic disease of the AV conduction system; this type of âcardiac syncopeâ is also ...
Milena Aste, Michele Brignole
doaj +1 more source
The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results. [PDF]
, 2015 Atrial fibrillation (AF) is the most common sustained arrhythmia in the general population. As an age-related arrhythmia AF is becoming a huge socio-economic burden for European healthcare systems. Despite significant progress in our understanding of the
Antoons, G +22 more
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The disease mutation A77V in Ryanodine receptor RyR2 induces changes in energy conduction pathways in the protein [PDF]
, 2011 Energetically responsive residues of the 217 amino acid N-terminal domain of the cardiac Ryanodine receptor RyR2 are identified by a simple elastic net model. These residues lie along a hydrogen bonded path through the protein.
Burak Erman, Nazan Walpoth
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Effects of Cardiac Structural Remodelling During Heart Failure on Cardiac Excitation – Insights from a Heterogeneous 3D Model of the Rabbit Atria [PDF]
, 2015 Heart failure is a leading cause of morbidity and mortality in the western world. One of the effects of heart failure is the structural remodelling of cardiac tissue, including tissue dilation and development of fibrosis.
Boyett, Mark +7 more
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Prevalence of Chagas Disease in a U.S. Population of Latin American Immigrants with Conduction Abnormalities on Electrocardiogram. [PDF]
PLoS Neglected Tropical Diseases, 2017 Chagas disease (CD) affects over six million people and is a leading cause of cardiomyopathy in Latin America. Given recent migration trends, there is a large population at risk in the United States (US).
Mahmoud I Traina +9 more
doaj +1 more source
Emerging from the Darkness. Sudden Cardiac Death in Cardiac Amyloidosis
Reviews in Cardiovascular Medicine, 2022 Cardiac amyloidosis (CA) manifests as infiltrative cardiomyopathy with a hypertrophic pattern, usually presenting with heart failure with a preserved ejection fraction. In addition, degenerative valvular heart disease, particularly severe aortic stenosis,
Valeria Cammalleri +11 more
doaj +1 more source