Results 231 to 240 of about 577,063 (338)

Cardiomyocyte cell cycle dynamics and proliferation revealed through cardiac-specific transgenesis of fluorescent ubiquitinated cell cycle indicator (FUCCI)

, 2018
Roberto Álvarez, Bingyan Wang, Pearl Quijada, Daniele Avitabile, Thi Ho, Maya Shaitrit, Monica Chavarria, Fareheh Firouzi, David Ebeid, Megan Monsanto, Natalie Navarrete, Maryam Moshref, Sailay Siddiqi, Kathleen M. Broughton, Barbara Bailey, Natalie Gude, Mark A. Sussman   +16 more
openalex   +2 more sources

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Cardiovascular Effects of Tourniquet Application with Cardiac Cycle Efficiency: A Prospective Observational Study. [PDF]

J Clin Med
Seker M, Aktas Yildirim S, Ulugol H, Gucyetmez B, Toraman F.   +4 more
europepmc   +1 more source

Direct Contact Between Human Cardiac Fibroblasts and Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Counteracts Changes in Calcium Cycling Induced by Soluble Mediators [PDF]

, 2014
Christopher Kane, Nicola Hellen, Tatiana Trantidou, Patrizia Camelliti, Cesare M. Terracciano   +4 more
openalex   +1 more source

Smart Hydrogel Doped by Metal–Organic Frameworks for Renewable Self‐Pumping Enzymatic Reactors

Advanced Science, EarlyView.
Renewable self‐pumping enzymatic reactors based on thermo‐stimulated cyclic contraction/expansion of metal‐organic frameworks‐doped hydrogel. Abstract The construction of high‐performance immobilized enzymes is vastly desired for green biotransformation.
Yuxi Zhu, Shenghao Wang, Yueyuan Luo, Linbo Cao, Xiuxiu Guo, Yue Zhang, Mingmin Li, Tie Wang   +7 more
wiley   +1 more source

Timing along the cardiac cycle modulates neural signals of reward-based learning. [PDF]

Nat Commun
Fouragnan EF, Hosking B, Cheung Y, Prakash B, Rushworth M, Sel A.   +5 more
europepmc   +1 more source

The volume-dependency of parallel conductance throughout the cardiac cycle and its consequence for volume estimation of the left ventricle in patients [PDF]

, 2001
Lilian Kornet
openalex   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Influence of cardiac cycle on myocardial extracellular volume fraction measurements with dual-layer computed tomography. [PDF]

Quant Imaging Med Surg
Nishigake D, Yamasaki Y, Hida T, Shirasaka T, Funatsu R, Kato T, Ishigami K.   +6 more
europepmc   +1 more source

Interplay between Ca2+ cycling and mitochondrial permeability transition pores promotes reperfusion-induced injury of cardiac myocytes

, 2010
Yaser Abdallah, S KASSECKERT, Wisam Iraqi, Maher Said, Tayyab Shahzad, Ali Erdoğan, Christiane Neuhof, Dursun Gündüz, Klaus‐Dieter Schlüter, Harald Tillmanns, H. M. Piper, H. Peter Reusch, Yury Ladilov   +12 more
openalex   +1 more source