Results 241 to 250 of about 534,991 (349)

AORTIC ROOT DYNAMICS DURING THE CARDIAC CYCLE

open access: bronze, 2000
Yu Shomura   +3 more
openalex   +1 more source

P21‐Activated Kinase 2 as a Novel Target for Ventricular Tachyarrhythmias Associated with Cardiac Adrenergic Stress and Hypertrophy

open access: yesAdvanced Science, EarlyView.
Ca2+/calmodulin‐dependent kinase II (CaMKII) activation is likely driven by oxidative stress, particularly excessive reactive oxygen species (ROS) production. This study identifies P21‐activated kinase 2 (Pak2) as a novel regulator of ROS‐induced CaMKII activation and abnormal Ca2⁺ dynamics in acute adrenergic and chronic pressure‐overload stressed ...
Tao Li   +21 more
wiley   +1 more source

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

open access: yesAdvanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

Improving osteoporosis treatment rates in inpatients admitted with hip fracture: A healthcare improvement initiative in a tertiary referral hospital

open access: yesAGING MEDICINE, Volume 5, Issue 4, Page 264-271, December 2022., 2022
Our hospital introduced a standardized protocol for the treatment of osteoporosis in patients admitted for hip fracture. The aim of this article was to describe its implementation as well as assess the protocol's effect on treatment rates and safety. In our analysis, there was significant improvement in treatment rates with no instances of acute kidney
Andrew Gan Lin   +5 more
wiley   +1 more source

Microneedles at the Forefront of Next Generation Theranostics

open access: yesAdvanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang   +8 more
wiley   +1 more source

Timing along the cardiac cycle modulates neural signals of reward-based learning. [PDF]

open access: yesNat Commun
Fouragnan EF   +5 more
europepmc   +1 more source

Cardiac cycle-dependent changes in aortic area and distensibility are reduced in older patients with isolated diastolic heart failure and correlate with exercise intolerance

open access: bronze, 2001
W. Gregory Hundley   +8 more
openalex   +1 more source

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