Results 251 to 260 of about 534,991 (349)

Conditional Overexpression of Serpine2 Promotes Hair Cell Regeneration from Lgr5+ Progenitors in the Neonatal Mouse Cochlea

Advanced Science, EarlyView.
This study indicates that Serpine2 plays a pivotal role in hair cell (HC) regeneration from Lgr5+ progenitors in the neonatal mouse cochlea. Conditional overexpression of Serpine2 in cochlear Lgr5+ progenitors results in a significantly increased number of ectopic HCs, particularly ectopic inner HCs, and these HCs are likely derived from Lgr5 ...
Hairong Xiao, Jiheng Wu, Lixuan Huang, Ying Ma, Leilei Wu, Yanqin Lin, Zixuan Ye, Xin Tan, Xujun Tang, Wei Tong, Mingchen Dai, Yintao Wang, Xia Sheng, Renjie Chai, Shasha Zhang   +14 more
wiley   +1 more source

Influence of cardiac cycle on myocardial extracellular volume fraction measurements with dual-layer computed tomography. [PDF]

Quant Imaging Med Surg
Nishigake D, Yamasaki Y, Hida T, Shirasaka T, Funatsu R, Kato T, Ishigami K.   +6 more
europepmc   +1 more source

Dysregulation of Cardiogenesis, Cardiac Conduction, and Cell Cycle in Mice Lacking miRNA-1-2 [PDF]

, 2007
Yong Zhao, J. Ransom, Ankang Li, Vasanth Vedantham, Morgan von Drehle, Alecia N. Muth, Takatoshi Tsuchihashi, Michael T. McManus, Robert J. Schwartz, Deepak Srivastava   +9 more
openalex   +1 more source

Depletion of Hepatic SREBP2 Protects Against Hypercholesterolemia and Atherosclerosis through the ANGPTL3‐LPL Axis

Advanced Science, EarlyView.
This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang, Jia You Sarafina Choe, Yu Shi, Thi Tun Thi, Xiaoyun Cao, Yang Hu, Kai Yan Cheng, Hui Li, Yang Ji, Yan Liu, Matthew Ackers‐Johnson, Roger S.Y. Foo, Yujia Shen, Haojie Yu   +13 more
wiley   +1 more source

Quantification of morpho-hemodynamic changes in unruptured intracranial aneurysms with irregular pulsation during the cardiac cycle using 4D-CTA. [PDF]

Front Neurol
Chen S, Zhang W, Cheng Y, Wang G, Lv N.
europepmc   +1 more source

Magnetic resonance imaging analysis of cardiac cycle events in diabetic rats: the effect of angiotensin‐converting enzyme inhibition

, 2002
Ahmad I. Al‐Shafei, Richard G. Wise, G. A. Gresham, T. A. Carpenter, Lars Häll, Christopher Huang   +5 more
openalex   +1 more source

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

Advanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong, Pei Li, Yi Jiang, Zhihan Wang, Shihui Fu, Hebin Che, Meng Liu, Xiaojing Zhao, Chunlei Liu, Chenghui Zhao, Qin Zhong, Chongyou Rao, Siwei Wang, Suyuan Liu, Dayu Hu, Dongjin Wang, Juntao Gao, Kai Guo, Xinwang Liu, En Zhu, Kunlun He   +20 more
wiley   +1 more source

Blood shear stress during the cardiac cycle and endothelial cell orientation and polarity in the carotid artery of male and female mice. [PDF]

Front Physiol
Nicolas N, de Tilly A, Roux E.
europepmc   +1 more source

PIP ₃ inhibition of RGS protein and its reversal by Ca ²⁺ /calmodulin mediate voltage-dependent control of the G protein cycle in a cardiac K ⁺ channel

, 2002
Masaru Ishii, Atsushi Inanobe, Yoshihisa Kurachi   +2 more
openalex   +1 more source

Manipulating myocyte cell cycle control for cardiac repair [PDF]

, 2008
Thomas A. Gorr, Alexander Deten
openalex   +1 more source