Results 251 to 260 of about 568,260 (340)

Improvement of Hemocompatibility in Passive Cardiovascular Implant Devices

Advanced Therapeutics, EarlyView.
With the ever‐increasing reliance on cardiovascular devices and implants, minimizing their impact on blood is vital for their continued success. This review investigates the common methods of tackling this challenge through careful selections of material and surface modifications.
Shiyen L. Perera, Christoph E. Hagemeyer, Julian A. Smith, Josie Carberry, Be'eri Niego   +4 more
wiley   +1 more source

Cardiomyocyte cell cycle dynamics and proliferation revealed through cardiac-specific transgenesis of fluorescent ubiquitinated cell cycle indicator (FUCCI)

, 2018
Roberto Álvarez, Bingyan Wang, Pearl Quijada, Daniele Avitabile, Thi Ho, Maya Shaitrit, Monica Chavarria, Fareheh Firouzi, David Ebeid, Megan Monsanto, Natalie Navarrete, Maryam Moshref, Sailay Siddiqi, Kathleen M. Broughton, Barbara Bailey, Natalie Gude, Mark A. Sussman   +16 more
openalex   +2 more sources

Elderly Liver Grafts are More Susceptible to Ischemia‐Reperfusion After Prolonged Cold Ischemia than Grafts from Young Donors—An Ex Vivo Liver Machine Perfusion Analysis in Sprague Dawley Rats

Advanced Therapeutics, EarlyView.
This study investigates how donor age and cold ischemia time influence liver perfusion parameters and injury markers. Older livers are more susceptible to longer ischemia times displaying more tissue damage, and higher expression of oxidative stress and apoptosis‐related proteins than livers with shorter ischemia times.
Leonard Boerger, Kilian A. Walter, Anna S. Pietsch, Linda Gilles, Oliver Klein, Karl H. Hillebrandt, Joseph M. G. V. Gassner, Jasper Iske, Johann Pratschke, Felix Krenzien, Igor M. Sauer, Nathanael Raschzok, Simon Moosburner   +12 more
wiley   +1 more source

The Importance of Electrovectorcardiographic Assessment of Intraventricular Blocks and their Relationship with the Cardiac Cycle. [PDF]

Arq Bras Cardiol
Pastore CA.
europepmc   +1 more source

CRISPR‐MI and scRNA‐Seq Reveal TREM2's Function in Monocyte Infiltration and Macrophage Apoptosis During Abdominal Aortic Aneurysm Development

Advanced Science, EarlyView.
A method is developed for conducting genome‐wide CRISPR/Cas9 screening of monocyte infiltration in vivo (CRISPR‐MI) that is easily adaptable across a variety of disease models. Through the combination of CRISPR‐MI and scRNA‐Seq, this study discovers that Trem2 is a key regulator of early monocyte infiltration in abdominal aortic aneurysm (AAA ...
Haocheng Lu, Chao Xue, Yang Zhao, Jinjian Sun, Changzhi Zhao, Xu Zhang, Guizhen Zhao, Yaozhong Liu, Hongyu Liu, Yongjie Deng, Ying Wang, Chi Zhang, Yingjie Liu, Linjun Zeng, Ying Yang, Bolun Li, Shusi Ding, Linkang Zhou, Henry Kuang, Zanxin Wang, Wenhao Ju, Haihuan Lin, Jie Lin, Yanhong Guo, Lin Chang, Hongmei Zhao, Jing Wang, Jiandie Lin, Lemin Zheng, Y. Eugene Chen, Jifeng Zhang   +30 more
wiley   +1 more source

Adaptation to Low-Intensity Exercise on a Cycle Ergometer by Patients With Acute Myocardial Infarction Undergoing Phase I Cardiac Rehabilitation

, 2004
Atsuhiko Matsunaga, Takashi Masuda, Misao Ogura, Masakazu Saitoh, Yusuke Kasahara, Takami Iwamura, Minako Yamaoka‐Tojo, Kiyotaka Sato, Tohru Izumi   +8 more
openalex   +2 more sources

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials

Advanced Science, EarlyView.
Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang, Pengfei Jiang, Joshua B Stein, Yannan Hou, Chaochen Zhou, Heemin Kang, Ki‐Bum Lee   +6 more
wiley   +1 more source

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

Advanced Science, EarlyView.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao, Huailong An, Cong Fan, Qingsu Lan, Hongyu Zhong, Yun Zhang, Libo Zhou, Panpan Hao   +7 more
wiley   +1 more source

The effect of isometric exercise on the systolic time intervals of the cardiac cycle

, 1972
Charles Dewey Harris
openalex   +1 more source