Results 251 to 260 of about 4,585,967 (340)

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

Relationship between cardiac cycle and the timing of actions during action execution and observation.

Cognition, 2021
Palser ER, Glass J, Fotopoulou A, Kilner JM.   +3 more
europepmc   +1 more source

Numerical Model of Full-Cardiac Cycle Hemodynamics in a Total Artificial Heart and the Effect of Its Size on Platelet Activation

Journal of Cardiovascular Translational Research, 2014
G. Marom, W. Chiu, Jessica R. Crosby, Katrina J. DeCook, Saurabh Prabhakar, M. Horner, M. Slepian, D. Bluestein   +7 more
semanticscholar   +1 more source

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

Advanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu, Qing Lu, Zixuan Fan, Jiahui Lin, Nan He, Xin Zhang, Zhaoya Han, Tingting Zhu, Zhenzhen Wu, Yingying Xu, Yuming Wang   +10 more
wiley   +1 more source

Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration

Cell, 2017
T. Mohamed, Yen-Sin Ang, E. Radzinsky, P. Zhou, Yu Huang, A. Elfenbein, A. Foley, S. Magnitsky, D. Srivastava   +8 more
semanticscholar   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Timing along the cardiac cycle modulates neural signals of reward-based learning

, 2022
Fouragnan E, Hosking B, Cheung Y, Prakash B, Rushworth M, Sel A.   +5 more
europepmc   +1 more source

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

Proceedings of the National Academy of Sciences of the United States of America, 2017
R. Mills, Drew Titmarsh, Xaver Koenig, B. Parker, J. Ryall, G. Quaife-Ryan, H. Voges, M. Hodson, C. Ferguson, L. Drowley, A. Plowright, E. Needham, Qing-Dong Wang, P. Gregorevic, Mei Xin, Walter G. Thomas, R. Parton, L. Nielsen, B. Launikonis, D. James, D. Elliott, E. Porrello, James E. Hudson   +22 more
semanticscholar   +1 more source

Genetics‐Based Targeting Strategies for Precise Neuromodulation

Advanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He, Zhidong Wei, Jianda Xu, Fei Jin, Tong Li, Lili Qian, Juan Ma, Weiying Zheng, Negar Javanmardi, Ting Wang, Kangjian Sun, Zhang‐Qi Feng   +11 more
wiley   +1 more source

The Importance of Electrovectorcardiographic Assessment of Intraventricular Blocks and their Relationship with the Cardiac Cycle. [PDF]

Arq Bras Cardiol
Pastore CA.
europepmc   +1 more source