Results 61 to 70 of about 576,151 (244)

Over expression of Plk1 does not induce cell division in rat cardiac myocytes in vitro.

PLoS ONE, 2009
BackgroundMammalian cardiac myocytes withdraw from the cell cycle during post-natal development, resulting in a non-proliferating, fully differentiated adult phenotype that is unable to repair damage to the myocardium, such as occurs following a ...
Carmen H Coxon, Katrina A Bicknell, Fleur L Moseley, Gavin Brooks   +3 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Tricuspid annulus: A spatial and temporal analysis

Annals of Cardiac Anaesthesia, 2016
Background: Traditional two-dimensional (2D) echocardiographic evaluation of tricuspid annulus (TA) dilation is based on single-frame measurements of the septolateral (S-L) dimension.
Ziyad O Knio, Mario Montealegre-Gallegos, Lu Yeh, Bilal Chaudary, Jelliffe Jeganathan, Robina Matyal, Kamal R Khabbaz, David C Liu, Venkatachalam Senthilnathan, Feroze Mahmood   +9 more
doaj   +1 more source

UCP2 modulates cardiomyocyte cell cycle activity, acetyl-CoA, and histone acetylation in response to moderate hypoxia

JCI Insight, 2022
Developmental cardiac tissue is regenerative while operating under low oxygen. After birth, ambient oxygen is associated with cardiomyocyte cell cycle exit and regeneration. Likewise, cardiac metabolism undergoes a shift with cardiac maturation.
Vagner O.C. Rigaud, Clare Zarka, Justin Kurian, Daria Harlamova, Andrea Elia, Nicole Kasatkin, Jaslyn Johnson, Michael Behanan, Lindsay Kraus, Hannah Pepper, Nathaniel W. Snyder, Sadia Mohsin, Steven R. Houser, Mohsin Khan   +13 more
doaj   +1 more source

Distinct effects of inflammation on preconditioning and regeneration of the adult zebrafish heart [PDF]

Open Biology, 2016
The adult heart is able to activate cardioprotective programmes and modifies its architecture in response to physiological or pathological changes. While mammalian cardiac remodelling often involves hypertrophic expansion, the adult zebrafish heart ...
Anne-Sophie de Preux Charles, Thomas Bise, Felix Baier, Jan Marro, Anna Jaźwińska   +4 more
doaj   +1 more source

Cardiac phase-resolved late gadolinium enhancement imaging

Frontiers in Cardiovascular Medicine, 2022
Late gadolinium enhancement (LGE) with cardiac magnetic resonance (CMR) imaging is the clinical reference for assessment of myocardial scar and focal fibrosis.
Sebastian Weingärtner, Ömer B. Demirel, Ömer B. Demirel, Francisco Gama, Iain Pierce, Thomas A. Treibel, Thomas A. Treibel, Jeanette Schulz-Menger, Jeanette Schulz-Menger, Mehmet Akçakaya, Mehmet Akçakaya   +10 more
doaj   +1 more source

INFLUENCE OF CARDIOVASCULAR RISK FACTORS ON AORTIC WALL MOTION AFTER REPAIR OF TYPE A AORTIC DISSECTION: AN ECG-GATED CT STUDY [PDF]

, 2012
OBJECTIVES: To evaluate aortic shape changes during cardiac cycle with dynamic computed tomographic angiography at important thoracic aorta anatomic landmarks in patients who previously underwent ascending aorta repair because of type A dissection, and ...
CROCCIA, MARIAGRAZIA
core  

Cyclic changes of blood echogenicity in high-frequency ultrasound [PDF]

, 1991
Ultrasound images from human arteries obtained in vivo with an intravascular 30 MHz ultrasound imaging device show that blood echogenicity changes during the cardiac cycle.
Bom, N. (Klaas), Gussenhoven, W.J. (Wilhelmina Johanna), Kroon, M.G.M. de, Roelandt, J.R.T.C. (Jos), Serruys, P.W.J.C. (Patrick), Slager, C.J. (Cornelis)   +5 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Aortic Wave Dynamics and Its Influence on Left Ventricular Workload [PDF]

, 2011
The pumping mechanism of the heart is pulsatile, so the heart generates pulsatile flow that enters into the compliant aorta in the form of pressure and flow waves.
Gharib, Morteza, Pahlevan, Niema M.
core   +4 more sources