Results 181 to 190 of about 928,242 (288)

An innovative in vitro model for studying the biology of cardiac fibroblasts originating from the epicardium. [PDF]

Dis Model Mech
Müller-Sánchez C, Muñiz-Banciella MG, Reina M, Soriano FX, Martínez-Estrada OM.   +4 more
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonist Use in Obese Patients Is Associated With Decreased Risk of Revision and Retears After Arthroscopic Rotator Cuff Repair

Arthroscopy, EarlyView.
Purpose To evaluate the impact of preoperative glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA) use on medical complications, emergency department use, and orthopaedic complications in obese patients undergoing arthroscopic rotator cuff repair. Methods Obese patients (defined by relevant ICD‐10 codes and confirmed by body mass index measurements ...
Argen Omurzakov, Arsen M. Omurzakov, Robert J. Burkhart, James E. Voos, Jacob G. Calcei, John M. Apostolakos   +5 more
wiley   +1 more source

Resolvin D1 attenuates senescence-associated secretory phenotype independently of TGF-β-driven cardiac fibroblasts differentiation to myofibroblast. [PDF]

J Inflamm (Lond)
Román M, Osorio JM, Espinoza-Pérez C, Machuca V, Peiró C, Ferrer CS, Vivar R, Díaz-Araya G.   +7 more
europepmc   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Autophagy gene regulation in cardiac myocytes and cardiac fibroblasts

Cardiovascular diseases rank as the primary cause of mortality worldwide, with myocardial infarction (MI) being a predominant contributor. MI results in extensive cardiomyocyte death and cardiac fibrosis development.
Nematisouldaragh , Darya
core  

Co-culturing hiPSC-cardiomyocytes and cardiac fibroblasts enhances engineered heart tissue structure and function. [PDF]

Stem Cells Transl Med
Luo Y, Parker J, Magaña AA, Sacayanan A, Huang K, Fernandes I, Keller GM, Backx PH, Foster LJ, Laksman Z.   +9 more
europepmc   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

Cannabidiol-induced Heme oxygenase-1 contributes to modulate the phenotype of hiPSC-derived cardiac fibroblasts from patients with Duchenne muscular dystrophy. [PDF]

Redox Biol
Savchenko L, Soussi S, Rovina D, Swiader A, Mallia S, Pompilio G, Kunduzova O, Parini A, Gowran A, Pizzinat N.   +9 more
europepmc   +1 more source

Human Fibroblast–Myeloid Cell Tissue Atlas Across the Lungs, Synovium, Skin, and Heart

Arthritis &Rheumatology, EarlyView.
Objective The availability of single‐cell RNA sequencing (scRNAseq) data in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald, Katerina Apostolopoulou, Olympia Hardy, Melpomeni Toitou, Gabriela Kania, Przemyslaw Blyszczuk, Raphael Micheroli, Thomas D. Otto, Mariola Kurowska‐Stolarska, Caroline Ospelt   +9 more
wiley   +1 more source

Single-cell and spatial transcriptomic profiling of cardiac fibroblasts following myocardial infarction. [PDF]

Sci Data
Hernández SC, Ainciburu M, Sudupe L, Planell N, López-Moreno M, Vilas-Zornoza A, Diaz-Martinez L, Cobos-Figueroa J, Romero JP, Sarvide S, San Martin-Uriz P, López-Pérez A, Abizanda G, Ripalda-Cemboráin P, Muinos-López E, Lagani V, Tegner J, Wu M, Janssens S, Pérez-Pomares JM, Prósper F, Ruiz-Villalba A, Gómez-Cabrero D.   +22 more
europepmc   +1 more source