Results 31 to 40 of about 42,032 (254)

Electrocardiographic Pad for Efficient Cardiac MR Gating [PDF]

Radiology, 2016
To assess feasibility and reliability of electrocardiographic (ECG)-gated cardiac magnetic resonance (MR) imaging with a simplified reusable electrode design that does not touch the skin.In this institutional review board-approved, HIPAA-compliant study, a silicon positioner held four ECG leads and detected ECG signals without requiring shaving ...
Nanda Deepa, Thimmappa, Mitchell A, Cooper, Thanh D, Nguyen, Silvina P, Dutruel, Keigo, Kawaji, Jonathan W, Weinsaft   +5 more
openaire   +2 more sources

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations

Nature Communications, 2022
Ryanodine receptor 2 (RyR2) is a Ca2+ release channel essential for cardiac excitation-contraction coupling. Here, the authors use structural and functional analysis to reveal RyR2 gating mechanism and its alterations by pathogenic mutations.
Takuya Kobayashi, Akihisa Tsutsumi, Nagomi Kurebayashi, Kei Saito, Masami Kodama, Takashi Sakurai, Masahide Kikkawa, Takashi Murayama, Haruo Ogawa   +8 more
doaj   +1 more source

A Heart Failure-Associated SCN5A Splice Variant Leads to a Reduction in Sodium Current Through Coupled-Gating With the Wild-Type Channel

Frontiers in Physiology, 2021
Nav1.5, encoded by the gene SCN5A, is the predominant voltage-gated sodium channel expressed in the heart. It initiates the cardiac action potential and thus is crucial for normal heart rhythm and function.
Yang Zheng, Yang Zheng, Xiaoping Wan, Dandan Yang, Angelina Ramirez-Navarro, Haiyan Liu, Ji-Dong Fu, Isabelle Deschênes   +7 more
doaj   +1 more source

Multislice Gated-Computed Tomography of Cardiac Paragangliomas

Journal of the American College of Cardiology, 2010
![Figure][1] [![Graphic][3] ][3][![Graphic][4] ][4] A 28-year-old man presented with paroxysmal hypertension (161/114 mm Hg) and tachycardia (131 beats/min). Urinary noradrenaline was 4,892 nmol/24 h (normal
Didier, Dominique, Meyer, Patrick, Philippe, Jacques   +2 more
openaire   +3 more sources

Fully Additive Vertical Organic Electrochemical Transistors on Renewable and Compostable Substrates Enable Ultrasensitive Bioelectronics

Advanced Functional Materials, EarlyView.
Fully additive vertical organic electrochemical transistors (vOECTs) with channel‐length of 226 nm on a 50 µm compostable substrate achieve >106 current modulation and ∼36 mS transconductance. Ion‐selective integration enables 1.1 mA dec−1 sensitivity and 36 µm detection limit, highlighting a scalable platform for sustainable electronics and ...
Giulia Frusconi, Samuele Lavelli, Zsolt M. Kovács‐Vajna, Fabrizio Torricelli   +3 more
wiley   +1 more source

Cardiorespiratory-gated cardiac proton radiotherapy using a novel ultrasound guidance system

Clinical and Translational Radiation Oncology
Cardiac stereotactic body radiotherapy is a promising noninvasive treatment for patients with refractory ventricular tachycardia. With the aim to prove feasibility of a novel image guided radiotherapy and heart motion gating device, cardiac proton ...
Keith A Cengel, Zayne Belal, Michele M Kim, Sarah Hagan, Saskia Camps, Alexander Kalinin, Weihow Hsue, Eric Diffenderfer, Adriano Garonna, Cory Tschabrunn   +9 more
doaj   +1 more source

Fetal Electrocardiogram (fECG) Gated MRI

Sensors, 2013
We have developed a Magnetic Resonance Imaging (MRI)-compatible system to enable gating of a scanner to the heartbeat of a foetus for cardiac, umbilical cord flow and other possible imaging applications.
Martyn N.J. Paley, Janet E. Morris, Debbie Jarvis, Paul D. Griffiths   +3 more
doaj   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

Advanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source