Results 121 to 130 of about 177,041 (162)
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Cardiac dilatation and hypertrophy
American Heart Journal, 1957Abstract Experimental and clinical evidence contrary to the theory of injury of the heart accompanying dilatation as a cause of cardiac hypertrophy is cited. Results from repetition and extension of the basic experiments from which the theory was launched fail to support the theory.
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Mitochondria and Cardiac Hypertrophy
2017Cardiac tissue responds to long-term hemodynamic load through initiation of a hypertrophic remodeling program. Importantly, if not counteracted this response will eventually lead to organ failure. Cardiac hypertrophic adaptations are complex, and involve multiple cellular events and the mechanisms underlying the development of cardiac hypertrophy are ...
Heberty di Tarso Fernandes, Facundo +3 more
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Modulation of Cardiac Hypertrophy by Estrogens
1997Gender-specific differences in heart disease have long been known but it has only been since the advent of molecular biology that it has become possible to investigate the molecular mechanisms. Most biochemical work in the last 50 years has focused on the characterization of the steroid hormones involved in gender specificity.
Pelzer, T. +4 more
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Proto-Oncogenes And Cardiac Hypertrophy
Annual Review of Physiology, 1989Generalized or focal myocardial hypenrophy is a component of most types of cardiac disease. Abnormalities of this growth process, which include in adequate, idiopathic, and pathological hypertrophy, have great clinical sig nificance. Postnatal heart enlargement is produced largely by increased size of striated muscle cells (hypertrophy) and increased
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The Coronary Circulation in Cardiac Hypertrophy
Journal of Cardiovascular Pharmacology, 1993Left ventricular hypertrophy is a common and important risk factor for cardiac mortality and morbidity. Cardiac hypertrophy adversely affects coronary perfusion because hypertension, its most frequent cause, is a major risk factor for coronary disease, and because cardiac hypertrophy may be associated with myocardial ischemia even in the absence of ...
D J, Sheridan, A, McAinsh, D J, O'Gorman
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Heart failure and cardiac hypertrophy
Current Treatment Options in Cardiovascular Medicine, 2007Left ventricular failure is the final common pathway for a wide spectrum of myocardial insults, including systemic hypertension and myocardial infarction. Although left ventricular hypertrophy is an adaptive response to pressure and volume overload, this process becomes maladaptive if left untreated and pathologic cardiac hypertrophy then becomes an ...
J Eduardo, Rame, Daniel L, Dries
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Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential
Nature Reviews Cardiology, 2023Thomas G Martin +2 more
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The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure
Cell Metabolism, 2021Ahmad A Cluntun +2 more
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USP25 Ameliorates Pathological Cardiac Hypertrophy by Stabilizing SERCA2a in Cardiomyocytes
Circulation Research, 2023Bozhi Ye, Yanghao Chen, Wante Lin
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