Results 61 to 70 of about 748,174 (294)

The Napkin-Ring Sign – the Story Behind Invasive Coronary Angiography

Journal of Interdisciplinary Medicine, 2021
Coronary artery disease (CAD) represents one of the leading causes of morbidity and mortality across Europe. Most of the patients do not experience any warning sign before the coronary event develops, therefore screening this group of patients is ...
Parajkó Zsolt, Kovacs István, Chițu Monica, Benedek Imre   +3 more
doaj   +1 more source

Effects of human recombinant growth hormone on exercise capacity, cardiac structure, and cardiac function in patients with adult-onset growth hormone deficiency [PDF]

, 2017
Objective Epidemiological studies suggest that adult-onset growth hormone deficiency (AGHD) might increase the risk of death from cardiovascular causes. Methods This was a 6-month double-blind, placebo-controlled, randomised, cross-over trial followed by
Atkin, S. L., Atkin, Stephen, Clark, AL, Clark, Andrew, Gonzalez, S., Gonzalez, Susana, Javed, Z., Javed, Zeeshan, Sathyapalan, T., Sathyapalan, Thozhukat, Windram, Hull, Windram, J. D.   +11 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Serial Correlations in Single-Subject fMRI with Sub-Second TR

, 2017
When performing statistical analysis of single-subject fMRI data, serial correlations need to be taken into account to allow for valid inference. Otherwise, the variability in the parameter estimates might be under-estimated resulting in increased false ...
Barth, Markus, Bollmann, Saskia, Cunnington, Ross, Pucket, Alexander M.   +3 more
core   +1 more source

Rationale and design of the Clinical Evaluation of Magnetic Resonance Imaging in Coronary heart disease 2 trial (CE-MARC 2): a prospective, multicenter, randomized trial of diagnostic strategies in suspected coronary heart disease [PDF]

, 2015
Background: A number of investigative strategies exist for the diagnosis of coronary heart disease (CHD). Despite the widespread availability of noninvasive imaging, invasive angiography is commonly used early in the diagnostic pathway.
Berry, Colin, Bijsterveld, Petra, Brown, Julia, Everett, Colin C., Greenwood, John P., McCann, Gerry P., Plein, Sven, Ripley, David P., Sculpher, Mark, Walker, Simon   +9 more
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Learning the dynamics and time-recursive boundary detection of deformable objects [PDF]

, 2008
We propose a principled framework for recursively segmenting deformable objects across a sequence of frames. We demonstrate the usefulness of this method on left ventricular segmentation across a cardiac cycle.
Cetin, Mujdat, Chan, Raymond, Sun, Walter, Willsky, Alan S., Çetin, Müjdat   +4 more
core   +4 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Neural-Network-Based Diagnosis Using 3-Dimensional Myocardial Architecture and Deformation: Demonstration for the Differentiation of Hypertrophic Cardiomyopathy

Frontiers in Cardiovascular Medicine, 2020
The diagnosis of cardiomyopathy states may benefit from machine-learning (ML) based approaches, particularly to distinguish those states with similar phenotypic characteristics.
Alessandro Satriano, Yarmaghan Afzal, Muhammad Sarim Afzal, Ali Fatehi Hassanabad, Cody Wu, Steven Dykstra, Jacqueline Flewitt, Jacqueline Flewitt, Jacqueline Flewitt, Patricia Feuchter, Rosa Sandonato, Bobak Heydari, Naeem Merchant, Naeem Merchant, Naeem Merchant, Andrew G. Howarth, Andrew G. Howarth, Andrew G. Howarth, Carmen P. Lydell, Carmen P. Lydell, Carmen P. Lydell, Aneal Khan, Nowell M. Fine, Russell Greiner, Russell Greiner, James A. White, James A. White, James A. White   +27 more
doaj   +1 more source

Cardiovascular Risk Factors from Another Point of View

Journal of Interdisciplinary Medicine, 2021
Cardiovascular diseases remain the main cause of death in western societies. This contributes to the appearance of new diagnostic and treatment methods addressed to reduce the burden of cardiovascular diseases.
Oltean Péter Balázs, Kovács István, Hodas Roxana, Benedek Theodora   +3 more
doaj   +1 more source