Results 101 to 110 of about 2,762,775 (250)

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Improving the efficiency and accuracy of cardiovascular magnetic resonance with artificial intelligence-review of evidence and proposition of a roadmap to clinical translation

Background Cardiovascular magnetic resonance (CMR) is an important imaging modality for the assessment of heart disease; however, limitations of CMR include long exam times and high complexity compared to other cardiac imaging modalities.
Wang, Yu, Zhang, Qiang, Fotaki, Anastasia, Prieto, Claudia, Doneva, Mariya, Wetzl, Jens, Ghadimi, Sona, Epstein, Frederick H, Delfino, Jana G, O'Regan, Declan P   +9 more
core   +1 more source

Modular Metamaterials for Adaptable MRI Signal Control: Combining Dipole Array With a New Hexagon‐Based Artificial Dielectrics

Advanced Science, EarlyView.
A flexible, hexagonally packed artificial dielectric providing a wide range of effective permittivities (εr ≈ 30–1400) without lumped elements was developed for clinical and ultra‐high‐field MRI. Combined with modular passive‐dipole arrays, the system enables adaptable RF field shaping through electric‐ and magnetic‐dipole tuning.
Santosh Kumar Maurya, Ilan Goldberg, Rita Schmidt   +2 more
wiley   +1 more source

Myocardial Viability on Cardiac Magnetic Resonance

Arquivos Brasileiros de Cardiologia
The study of myocardial viability is of great importance in the orientation and management of patients requiring myocardial revascularization or angioplasty. The technique of delayed enhancement (DE) is accurate and has transformed the study of viability
Ana Luiza Mansur Souto, Rafael Mansur Souto, Isabella Cristina Resende Teixeira, Marcelo Souto Nacif   +3 more
doaj   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

Improving Cardiac Magnetic Resonance Scanning Efficiency

JACC: Case Reports
Background: Cardiovascular magnetic resonance (CMR) imaging access is bottlenecked by prolonged scan times and limited specialist availability. Project Rationale: We aimed to optimize clinical workflows by implementing a dual-intervention strategy ...
Esosa Odigie-Okon, MD, MSc, Olushola Ogunleye, MD, MPH, Ritika Saxena, BDS, MPH, Dallin Swanson, BS, Sindhuja Earagolla, BS, Neha Sunkara, BS, Sahil Bhargava, MD, Yumna Furqan, MD, Avery Love, DO   +8 more
doaj   +1 more source

A level-set reformulated as deep recurrent network for left/right ventricle segmentation on cardiac cine MRI

, 2020
We proposed a segmentation method, which is based on a level-set reformulated via a deep recurrent network (RLSNet). This network takes the advantage of U-Net in terms of medical pattern recognition and level-set algorithm in terms of keeping the ...
Ng, MY, Huang, F, Khong, PL, Cao, P, Vardhanabhuti, V   +4 more
core  

Do we need invasive confirmation of cardiac magnetic resonance results?

, 2017
Introduction : Coronary artery revascularization is indicated in patients with documented significant obstruction of coronary blood flow associated with a large area of myocardial ischemia and/or untreatable symptoms.
Paweł Siastała, Jacek Kądziela, Mateusz Śpiewak, Adam Witkowski, Katarzyna Lech, Łukasz A. Małek   +5 more
core   +1 more source