Results 201 to 210 of about 93,083 (312)

Ca²⁺ microdomain-based excitation-transcription coupling in cardiac myocytes and vascular smooth muscle cells. [PDF]

Inflamm Regen
Koide T, Giles WR, Kondo R, Imaizumi Y, Yamamura H, Suzuki Y.   +5 more
europepmc   +1 more source

Healthy cardiac myocytes can decrease sympathetic hyperexcitability in the early stages of hypertension. [PDF]

Front Synaptic Neurosci, 2022
Davis H, Liu K, Li N, Li D, Paterson DJ.
europepmc   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Distinct intracellular spatiotemporal expression of Calmodulin genes underlies functional diversity of Calmodulin-dependent signalling in cardiac myocytes. [PDF]

Cardiovasc Res
Bogdanov V, Mariangelo JIE, Soltisz AM, Sakuta G, Pokrass A, Beard C, Orengo BH, Kalinin R, Ulker A, Yunker B, Tikunova S, Thuma J, Xu X, Hund TJ, Veeraraghavan R, Davis JP, Györke S.   +16 more
europepmc   +1 more source

A stochastic mathematical model for coupling the cytosolic and sarcoplasmic calcium movements in diseased cardiac myocytes. [PDF]

Eur Biophys J, 2022
Arif S.
europepmc   +1 more source

Cellular mechanisms of radiation‐induced myocyte dysfunction: effects on calcium handling, ion channel regulation and mitochondrial energetics

The Journal of Physiology, EarlyView.
Abstract figure legend Dose‐dependent effects of radiation on cardiac electrophysiology and arrhythmia susceptibility. At low radiation doses (left), increased reactive oxygen species (ROS) initiate an ROS–Ca2+ positive feedback loop involving calcium/calmodulin‐dependent protein kinase II (CaMKII) activation, enhanced L‐type Ca2+ current (ICaL ...
Hannah M. Zukowski, Colleen E. Clancy
wiley   +1 more source

Nanoscale architecture and dynamics of Ca_V1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy. [PDF]

J Mol Cell Cardiol Plus
Schwenzer N, Tsukanov R, Kohl T, Basak S, Sobitov I, Seibertz F, Kapoor R, Voigt N, Enderlein J, Lehnart SE.   +9 more
europepmc   +1 more source

Mechanisms of cAMP compartmentation in cardiac myocytes: experimental and computational approaches to understanding. [PDF]

J Physiol, 2021
Harvey RD, Clancy CE.
europepmc   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Myosin binding protein-C modulates loaded sarcomere shortening in rodent permeabilized cardiac myocytes. [PDF]

J Gen Physiol
McDonald KS, Kalogeris TJ, Veteto AB, Davis DJ, Hanft LM.   +4 more
europepmc   +1 more source