Results 131 to 140 of about 26,349 (219)

Mechanisms and biomarkers of immune checkpoint inhibitor-associated myocarditis: from T cell imbalance to multicellular crosstalk. [PDF]

Front Immunol
Huang J, Xu X, Jin Y, Qiao L, Yu H, Gao W, Li C.   +6 more
europepmc   +1 more source

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

Cell Proliferation, Volume 59, Issue 8, August 2026.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik, Muhammad Dilawar, Junguang Liao, Jie Zheng, Qitao Qian, Ming Xu, Sisi Lin, Xiaobo Zhu, Qiuwei Ge, Limin Jin, Guiqian Chen   +10 more
wiley   +1 more source

Cardiac myosin inhibitors in hypertrophic cardiomyopathy: advancing care with caution

Annals of Medicine & Surgery
Zoya Rehman, Faisal Ahsaan, Bakhtawar Latif, Ahmad Furqan Anjum, Hermann Yokolo   +4 more
openaire   +2 more sources

Acute Myocarditis: From Pathophysiology to Risk‐Stratified Management—A Clinical Review

European Journal of Clinical Investigation, Volume 56, Issue 8, August 2026.
Stepwise approach to patients with suspected acute myocarditis, integrating the 2024 American College of Cardiology (ACC) four‐stage classification (Stages A–D) and the 2025 European Society of Cardiology (ESC) inflammatory myopericardial syndrome (IMPS) framework. Step 1 (Initial Assessment): clinical presentation, first‐line investigations (ECG, high‐
Michele Golino, Marco Giuseppe Del Buono, Michele Marchetta, Nicola Potere, Aldo Bonaventura, Alessandra Vecchiè, Danilo Malandrino, Giacomo Emmi, Jordana Kron, Antonio Abbate   +9 more
wiley   +1 more source

Incidence of Ventricular Arrhythmias and Sudden Cardiac Death with Cardiac Myosin Inhibitors in Hypertrophic Cardiomyopathy: A Meta-Analysis of Randomized Controlled Trials. [PDF]

J Pers Med
Katic J, Bulum T, Borovac JA.
europepmc   +1 more source

Aerobic Endurance Training Modulates Cardiac Renin‐Angiotensin System Peptides and Matrix Metalloproteinase Activity During Chronic Stress

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT To investigate the involvement of metalloproteinases (MMPs) in the context of endurance training and their interactions with renin‐angiotensin signalling (RAS) in stress‐induced pathophysiological responses. Trained rats were submitted to 8‐weeks of endurance treadmill training with chronic mild stress (CMS), TS rats, and without CMS (T).
Vinicius Guzzoni, Fabiana Gomes Ferreira, Lívia Bruni de Souza, Rebecca Salomão, Nicholas Kesler, Rodrigo Yokota, Nilsa Regina Damaceno‐Rodrigues, Elia Garcia Caldini, Fernanda Klein Marcondes, Rita de Cássia Marqueti, Steven T. Haller, David J. Kennedy, Lauren G. Koch, Dulce Elena Casarini, Tatiana Sousa Cunha   +14 more
wiley   +1 more source

Mavacamten as an Effective Treatment for HCM With Latent Exercise-Induced Obstruction: A Case Report. [PDF]

Case Rep Cardiol
Murthy N, Diep B, Evans J, Abramov D, Tran D.   +4 more
europepmc   +1 more source

Dietary nutgrass (Cyperus rotundus) extract–loaded chitosan nanoparticles: Enhance growth performance, boost immune responses, improve antioxidant capacity, and physiological performance in white leg shrimp (Litopenaeus vannamei)

Journal of the World Aquaculture Society, Volume 57, Issue 4, August 2026.
Abstract Aquaculture has increasingly turned toward plant extracts' usage as functional additives, owing to their rich content of bioactive compounds that enhance growth performance, boost immune responses, and improve antioxidant capacity in cultured species.
Nader N. Hassona, Nauman Khan, Maryam Alenize, Ahmed Tayel, Salma Elhussein, Jia Longwu, Huici Yang, Yun Li, Nusrat Liaqat, Xilin Dai   +9 more
wiley   +1 more source

Osimertinib induces reversible cardiac dysfunction through the GATA4-MYLK3-MYL2 axis. [PDF]

Eur Heart J
Zhang K, Ayala A, Norambuena-Soto I, Agnihotri V, Shu T, Nenninger C, Wang Y, Echevarria B, Aboagye J, Huang K, Espitia-Corredor J, Wu X, Chen ZB, Deng Y, Perry JJP, Raz DJ, Yang H, Cheng P, Fu G, Wang ZV, Rhee JW.   +20 more
europepmc   +1 more source

The Cavβ4 subunit of Cav1.2 channels antagonizes isoproterenol‐induced hypertrophy in rat cardiac muscle cells by down‐regulating miR‐183‐5p

Physiological Reports, Volume 14, Issue 15, August 2026.
Abstract The Cavβ4 subunit of voltage‐gated Cav1.2 channels regulates gene expression in neurons and cardiac cells. It increases the expression of interferon‐β–related genes in H9c2 cardiomyocytes derived from rat ventricular tissue, but the possibility that it also regulates the expression of microRNAs (miRs) remains unexplored.
Elba D. Carrillo, Erick Galicia, María C. García, Jorge A. Sánchez   +3 more
wiley   +1 more source