Results 231 to 240 of about 51,089 (251)

Structure of the native myosin filament in the relaxed cardiac sarcomere

Nature, 2023
Davide Tamborrini, Zhexin Wang, Thorsten Wagner   +2 more
exaly  

The effects of the cardiac myosin activator, omecamtiv mecarbil, on cardiac function in systolic heart failure: a double-blind, placebo-controlled, crossover, dose-ranging phase 2 trial

Lancet, The, 2011
John R Teerlink, Chim C Lang
exaly  

Dose-dependent augmentation of cardiac systolic function with the selective cardiac myosin activator, omecamtiv mecarbil: a first-in-man study

Lancet, The, 2011
John R Teerlink, Barry Greenberg
exaly  

Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers

Proceedings of the National Academy of Sciences of the United States of America, 2018
Darshan V Trivedi, Saswata S Sarkar, Weikang   +2 more
exaly  

Mavacamten stabilizes an autoinhibited state of two-headed cardiac myosin

Proceedings of the National Academy of Sciences of the United States of America, 2018
Osha Roopnarine, David D Thomas
exaly  

Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial

Lancet, The, 2016
John R Teerlink, G Michael Felker, Justin A Ezekowitz   +2 more
exaly  

A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation

Cell, 1990
Christine E Seidman
exaly  

AKT answer relating to cardiac myosin inhibitor interactions

InnovAiT: Education and inspiration for general practice
openaire   +1 more source

Myosin inhibitor flexes, myosin activator flops

Nature Reviews Drug Discovery, 2020
exaly  

Mutations in the Gene for Cardiac Myosin-Binding Protein C and Late-Onset Familial Hypertrophic Cardiomyopathy

New England Journal of Medicine, 1998
Hugh Christian Watkins, Albert E Chudley, William John McKenna   +2 more
exaly