Results 201 to 210 of about 910,276 (348)

Technical challenges and prospects for ex vivo heart perfusion: a republication of the review published in Japanese journal of artificial organs. [PDF]

J Artif Organs
Sakota D, Kosaka R, Nagaoka E, Tahara T, Ohuchi K, Kigata T, Sakanoue I, Fujita T, Okamoto T.   +8 more
europepmc   +1 more source

Comparison of Maximum Vasoactive Inotropic Score and Low Cardiac Output Syndrome As Markers of Early Postoperative Outcomes After Neonatal Cardiac Surgery

Pediatric Cardiology, 2012
R. Butts, M. Scheurer, A. Atz, S. Zyblewski, T. Hulsey, S. Bradley, E. Graham   +6 more
semanticscholar   +1 more source

Optimization of Magnetic Milli‐Spinner for Robotic Endovascular Intervention

Advanced Robotics Research, EarlyView.
This work presents the design optimization of a multifunctional magnetic milli‐spinner for high‐speed propulsion and efficient clot debulking. The optimized design achieves an ultrafast swimming velocity of 55 cm/s (≈175 body lengths/s) in saline water, enabling stable upstream swimming against strong physiological flows and establishing magnetic milli‐
Lu Lu, Luca Higgins, Jack Bernardo, Ruike Renee Zhao   +3 more
wiley   +1 more source

Immediate Postoperative Evolution of Cerebral Doppler and Saturation Parameters After Cardiopulmonary Bypass in Infants With Congenital Heart Disease: A Prospective Cohort Study. [PDF]

Crit Care Explor
Mir M, Maitre G, Dancea A, Bernier PL, Fontela P, Zavalkoff S, Roche Martínez A, O'Brien N, LaRovere KL, Shemie SD, Altit G.   +10 more
europepmc   +1 more source

IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury

Advanced Science, EarlyView.
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang, Qingchen Zhang, Yanrui Chen, Dapeng Yu, Ronghan Liu, Jianning Kang, Xiang Fang, Ying Zhang, Hong Bian, Yanxin Zhao, Yongcheng Yin, Ce Zhang, Yanfei Jia, Qingfa Chen, Yuepeng Fang, Shang Li, Fang Li, Zhengxin Jin, Bin Ning   +18 more
wiley   +1 more source

Peripartum cardiomyopathy in an intensive care unit setting. [PDF]

World J Crit Care Med
Zaidi SF, Prasad A, Gangadhar AM, Khan SA, Zaidi AH, Mushtaq M, Anil G, Surani S.   +7 more
europepmc   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Impact of FloTrac/EV1000-guided intraoperative hemodynamic optimization on postoperative outcomes in cardiac valve surgery: a randomized controlled trial. [PDF]

Sci Rep
Tribuddharat S, Ratanasuwan P, Sathitkarnmanee T, Chaimala N, Polsena L, Mantruad P.   +5 more
europepmc   +1 more source

Serum cortisol concentration with exploratory cut-off values do not predict the effects of hydrocortisone administration in children with low cardiac output after cardiac surgery.

Interactive Cardiovascular and Thoracic Surgery, 2012
E. Verweij, K. Hogenbirk, A. Roest, R. van Brempt, M. Hazekamp, E. de Jonge   +5 more
semanticscholar   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source