Results 261 to 270 of about 910,276 (348)

Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes

open access: yesAdvanced Science, EarlyView.
This review synthesizes advances in bone organoid engineering and evaluates their potential to model diabetic bone fragility. Current in vitro and animal models do not fully recapitulate diabetes‐associated skeletal phenotypes. Cell‐based and scaffold‐based bone organoids are discussed as complementary approaches to reconstruct multicellular bone ...
Shuangzhe Lin   +2 more
wiley   +1 more source

Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression

open access: yesAdvanced Science, EarlyView.
Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang   +11 more
wiley   +1 more source

Rationale and design of the REMECHOQUE multicentre registry protocol: evaluating therapeutic trends in cardiogenic shock. [PDF]

open access: yesBMJ Open
Jimenez-Franco V   +15 more
europepmc   +1 more source

Association between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model. [PDF]

open access: yesSci Rep
Sakamoto K   +15 more
europepmc   +1 more source

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