Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes
This review synthesizes advances in bone organoid engineering and evaluates their potential to model diabetic bone fragility. Current in vitro and animal models do not fully recapitulate diabetes‐associated skeletal phenotypes. Cell‐based and scaffold‐based bone organoids are discussed as complementary approaches to reconstruct multicellular bone ...
Shuangzhe Lin +2 more
wiley +1 more source
End-tidal carbon dioxide changes induced by passive leg raising can predict fluid responsiveness in patients on veno-arterial extracorporeal membrane oxygenation: a prospective, interventional study. [PDF]
Hannequin T +10 more
europepmc +1 more source
Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression
Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang +11 more
wiley +1 more source
Rationale and design of the REMECHOQUE multicentre registry protocol: evaluating therapeutic trends in cardiogenic shock. [PDF]
Jimenez-Franco V +15 more
europepmc +1 more source
Epidural Anesthesia for Cesarean Section in a Patient With Severe Dilated Cardiomyopathy: A Case Report. [PDF]
Amir M +4 more
europepmc +1 more source
Impact of timing for intra-aortic balloon pump insertion on patients undergoing mitral valve surgery. [PDF]
Du L +5 more
europepmc +1 more source
Extubation Failure after Pediatric Cardiac Surgery. [PDF]
Kapoor MC.
europepmc +1 more source
Association between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model. [PDF]
Sakamoto K +15 more
europepmc +1 more source
Pulmonary haemodynamics and right heart function during exercise at high versus low altitude in patients with pulmonary vascular disease: a randomised crossover trial. [PDF]
Müller J +8 more
europepmc +1 more source

