Results 91 to 100 of about 1,642,043 (400)

Future of smart cardiovascular implants [PDF]

, 2018
Cardiovascular disease remains the leading cause of death in Western society. Recent technological advances have opened the opportunity of developing new and innovative smart stent devices that have advanced electrical properties that can improve ...
Bussooa, Anubhav, Mercer, John R., Neale, Steven   +2 more
core   +1 more source

Repurposing With Purpose: Treatment of Bachmann–Bupp Syndrome With Eflornithine and Implications for Other Polyaminopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Rare diseases impact approximately 1 in 10 people worldwide, and yet, less than 5% of all rare diseases currently have an approved treatment option available. This is due to many challenges unique to rare diseases, including small, diverse patient populations, the cost of drug development that is not proportionate to the number of patients who
Caleb P. Bupp, Elizabeth A. VanSickle, Julianne Michael, Chad R. Schultz, Kelly Nguyen, Melissa Hoefer, Surender Rajasekaran, André S. Bachmann   +7 more
wiley   +1 more source

Meta-analysis of comprehensive prognostic evaluation in patients with atrial fibrillation complicated by heart failure after catheter ablation

Scientific Reports
Atrial fibrillation (AF) and heart failure (HF) often coexist, posing increased risks of HF events, rehospitalization, mortality, and stroke. While antiarrhythmic drugs have limitations, catheter ablation (CA) has emerged as a preferred rhythm control ...
Xiaoting Zhang, Meng Wei, Pengjie Xue, Baopeng Tang   +3 more
doaj   +1 more source

Rate-dependent propagation of cardiac action potentials in a one-dimensional fiber

, 2004
Action potential duration (APD) restitution, which relates APD to the preceding diastolic interval (DI), is a useful tool for predicting the onset of abnormal cardiac rhythms.
C. L. Gibbs, D. R. Chialvo, Daniel J. Gauthier, David G. Schaeffer, Elena G. Tolkacheva, J. D. Murray, John W. Cain, L. S. Gettes, M. R. Boyett, M. R. Guevara, M. Watanabe, V. Elharrar   +11 more
core   +1 more source

Permanent His Bundle Pacing for Cardiac Resynchronization Therapy in Patients With Heart Failure and Right Bundle Branch Block

Circulation: Arrhythmia and Electrophysiology, 2018
Background: Cardiac resynchronization therapy utilizing biventricular pacing is an effective therapy for patients with left ventricular (LV) systolic dysfunction, left bundle branch block, and heart failure.
Parikshit S. Sharma, Angela M Naperkowski, T. Bauch, J. Y. Chan, A. Arnold, Z. Whinnett, K. Ellenbogen, P. Vijayaraman   +7 more
semanticscholar   +1 more source

B cells and systemic sclerosis interstitial lung disease

Arthritis &Rheumatology, Accepted Article.
Interstitial lung disease is an important complication of systemic sclerosis (SSc‐ILD) with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to FDA‐approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of interstitial lung diseases of other systemic autoimmune ...
Nina Goldman, Voon Ong, Christopher Denton   +2 more
wiley   +1 more source

Reuse, Reduce, Recycle: the 21st century Mantra

Indian Pacing and Electrophysiology Journal, 2022
A. Manickavasagam, S.C.S. Patloori, H.T. Perla, D. Chase, J. Roshan   +4 more
doaj   +1 more source

Andersen-Tawil Syndrome [PDF]

, 2006
Andersen-Tawil syndrome (ATS) is a rare condition consisting of ventricular arrhythmias, periodic paralysis, and dysmorphic features. In 2001, mutations in KCNJ2, which encodes the α subunit of the potassium channel Kir2.1, were identified in patients ...
Fish, Frank A, Kannankeril, Prince J, Smith, Andrew H   +2 more
core   +2 more sources

Gamifying anatomy outreach: An underexplored opportunity

Anatomical Sciences Education, EarlyView.
Abstract This article explores the underutilized potential of incorporating gamified approaches into anatomy outreach initiatives. While gamification and game‐based learning approaches have been widely adopted in formal educational settings, there is a surprising lack of research on their application for community‐based public engagement with anatomy ...
Mikaela L. Stiver, Aamna Naveed, John Chilton, Siobhan M. Moyes   +3 more
wiley   +1 more source

DNA methylation-based telomere length is more strongly associated with cardiovascular disease and long-term mortality than quantitative polymerase chain reaction-based telomere length: evidence from the NHANES 1999–2002

Clinical Epigenetics
Background Telomere length (TL) serves as a pivotal gauge of cellular aging, with shorter TL linked to various age-related ailments. Recently, a DNA methylation-based TL estimator, known as DNAmTL, has emerged as a novel TL measurement tool.
Qianhui Wang, Yuanfeng Gao, Jie Song, Dilare Taiwaikuli, Huanhuan Ding, Xinchun Yang, Baopeng Tang, Xianhui Zhou   +7 more
doaj   +1 more source