Results 91 to 100 of about 100,983 (296)

Severe, Non‐apneic Respiratory Dysfunction and Hypoxia following Generalized Convulsive Seizures

Annals of Neurology, EarlyView.
Objective Sudden unexpected death in epilepsy (SUDEP) is a devastating consequence of some generalized convulsive seizures (GCS). Recent work has focused on seizure related apnea as a biomarker of SUDEP risk, frequently without characterizing the adequacy of non‐apneic ventilation or identifying other dysfunctional breathing patterns.
Haley E. Pysick, Rup K. Sainju, Roshni Nair, Deidre N. Dragon, Eduardo Bravo, Laura Vilella, Xiaojin Li, Samden D. Lhatoo, George B. Richerson, Brian K. Gehlbach   +9 more
wiley   +1 more source

Prescribing competence: The pros and cons of different methods for assessment

British Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman, Erik M. Donker, Jelle Tichelaar, on behalf of the CP4T programme   +3 more
wiley   +1 more source

A Predictive Model and Scoring System for All-Cause Mortality in Patients With Atrial Fibrillation Combined With Obstructive Sleep Apnea Syndrome: A Retrospective Case–Control Study

Reviews in Cardiovascular Medicine
Background: The high prevalence and mortality rate of combined atrial fibrillation (AF) and obstructive sleep apnea syndrome (OSAS) impose a significant disease burden on public healthcare systems. However, there is currently a lack of
Xiaoting Zhang, Meng Wei, Pengjie Xue, Yanmei Lu, Baopeng Tang   +4 more
doaj   +1 more source

The role of gap junctions in cardioprotection against the ischaemia and reperfusion-induced severe ventricular arrhythmias [PDF]

, 2018
Ventricular tachyarrhythmias are one of the main causes responsible for sudden cardiac death. The prevention and treatment of these severe arrhythmias are still remained a challenge of cardiology in the industrialized countries.
Miskolczi Gottfried
core  

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Personal HealthCare of Things: A novel paradigm and futuristic approach

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract This study provides an investigative approach and offers a complete review of research on Internet of Medical Things (IoMT), describing the progress in general and highlighting the research issues, trends, and future aspects of IoMT. Exploring a research strategy for IoMT systems is vital as the need for IoT in healthcare grows. By aggregating
Surbhi Gupta, Mohammad Shabaz, Ankur Gupta, Abdullah Alqahtani, Shtwai Alsubai, Isaac Ofori   +5 more
wiley   +1 more source

DNA methylation-based telomere length is more strongly associated with long-term all-cause mortality than quantitative polymerase chain reaction-based telomere length among middle-aged and older hypertensive adults

Clinical Epigenetics
Background Telomere length (TL) has been linked to mortality risk across various populations. However, its predictive value for mortality risk specifically in hypertensive adults remains unclear. Methods This cohort study utilized data from the 1999–2000
Qianhui Wang, Yuanfeng Gao, Dilare Taiwaikuli, Huanhuan Ding, Jie Song, Xinchun Yang, Baopeng Tang, Xianhui Zhou   +7 more
doaj   +1 more source

Intermittently “Pre-Excited” ECG after Accessory Pathway Ablation: Unsuccessful Procedure or a Complication?

Case Reports in Cardiology, 2012
A 52-year-old woman with previously unsuccessful posteroseptal pathway ablation using radiofrequency energy presented with intermittently occurring short PR followed by a wide QRS complex, and complaining of palpitations with characteristics different ...
Evgeny Mikhaylov, Elnara Voitkovskaya, Dmitry Lebedev   +2 more
doaj   +1 more source

Cardiac parasympathetic modulation in the setting of radiofrequency ablation for atrial fibrillation

Archives of Medical Science, 2019
The cardiac autonomic nervous system plays an important role in the genesis and maintenance of atrial fibrillation. Although, pulmonary vein isolation is the cornerstone in today’s approach to atrial fibrillation ablation, a considerable proportion of ...
Thiago G. Osório, Gaetano Paparella, Sebastian Stec, Gian Battista Chierchia, Carlo de Asmundis   +4 more
doaj   +1 more source

The role of M cells and the long QT syndrome in cardiac arrhythmias: simulation studies of reentrant excitations using a detailed electrophysiological model

, 2004
In this numerical study, we investigate the role of intrinsic heterogeneities of cardiac tissue due to M cells in the generation and maintenance of reentrant excitations using the detailed Luo-Rudy dynamic model. This model has been extended to include a
Cherry E. M., Diego J. M. D., Hervé Henry, Wouter-Jan Rappel   +3 more
core   +1 more source