Results 141 to 150 of about 1,622,247 (397)

Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial

ESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad, Jeanne du Fay de Lavallaz, Michael J. Zhang, Thanat Chaikijurajai, Bo Ye, Prabhjot S. Nijjar, Julie A. Lahiri, Cindy M. Martin, Tamas Alexy, Markus Meyer   +9 more
wiley   +1 more source

Predicting and Recognizing Drug‐Induced Type I Brugada Pattern Using ECG‐Based Deep Learning

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Brugada syndrome (BrS) has been associated with sudden cardiac death in otherwise healthy subjects, and drug‐induced BrS accounts for 55% to 70% of all patients with BrS.
Paul‐Adrian Călburean, Luigi Pannone, Cinzia Monaco, Domenico Della Rocca, Antonio Sorgente, Alexandre Almorad, Gezim Bala, Filippo Aglietti, Robbert Ramak, Ingrid Overeinder, Erwin Ströker, Gudrun Pappaert, Marius Măru’teri, Marius Harpa, Mark La Meir, Pedro Brugada, Juan Sieira, Andrea Sarkozy, Gian‐Battista Chierchia, Carlo de Asmundis   +19 more
doaj   +1 more source

Gene Therapy in Cardiac Arrhythmias [PDF]

, 2006
Gene therapy has progressed from a dream to a bedside reality in quite a few human diseases. From its first application in adenosine deaminase deficiency, through the years, its application has evolved to vascular angiogenesis and cardiac arrhythmias.
Francis, Johnson, Praveen, S.V, Venugopal, K   +2 more
core  

Early occurrence of heart failure hospitalization or ventricular arrhythmia re‐define the long‐term prognosis after CRT

ESC Heart Failure, EarlyView.
Abstract Aims Classifying patients as responders or non‐responders to cardiac resynchronization therapy (CRT) has been recently challenged, suggesting that preventing heart failure (HF) progression may also provide survival benefits. We assessed a novel classification based on echocardiographic left ventricular (LV) reverse remodelling and the ...
Anna Zsofia Toth, Laszlo Nagy, Krisztina Maria Szabo, Vivien Racz, Alexandra Kiss, Gabor Sandorfi, Attila Borbely, Tibor Laszlo Nagy, Zoltan Csanadi   +8 more
wiley   +1 more source

Personal HealthCare of Things: A novel paradigm and futuristic approach

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract This study provides an investigative approach and offers a complete review of research on Internet of Medical Things (IoMT), describing the progress in general and highlighting the research issues, trends, and future aspects of IoMT. Exploring a research strategy for IoMT systems is vital as the need for IoT in healthcare grows. By aggregating
Surbhi Gupta, Mohammad Shabaz, Ankur Gupta, Abdullah Alqahtani, Shtwai Alsubai, Isaac Ofori   +5 more
wiley   +1 more source

Analysis of immunoinfiltration and EndoMT based on TGF-β signaling pathway-related genes in acute myocardial infarction

Scientific Reports
Acute myocardial infarction (AMI), a critical manifestation of coronary heart disease, presents a complex and not entirely understood etiology. This study investigates the potential role of immune infiltration and endothelial-mesenchymal transition ...
Jun Shen, Junqing Liang, Manzeremu Rejiepu, Zhiqin Ma, Jixian Zhao, Jia Li, Ling Zhang, Ping Yuan, Jianing Wang, Baopeng Tang   +9 more
doaj   +1 more source

Immune Checkpoint Inhibitors and Cardiovascular Adverse Events

ESC Heart Failure, EarlyView.
Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna, Elia Rigamonti, Raffaele Zannoni, Vittoria Espeli, Giorgio Moschovitis   +4 more
wiley   +1 more source

Rabbit models of heart disease. [PDF]

, 2008
Human heart disease is a major cause of death and disability. A variety of animal models of cardiac disease have been developed to better understand the etiology, cellular and molecular mechanisms of cardiac dysfunction and novel therapeutic strategies ...
Bers, Donald M, Pogwizd, Steven M
core  

Takotsubo cardiomyopathy during armed conflict: A case series

ESC Heart Failure, Volume 12, Issue 2, Page 1494-1498, April 2025.
Sharon Bruoha, Artyom Star, Gili Givaty, Michael Shilo, Michael Friger, Vladimir Chitoroga, Hezzy Shmueli, Yigal Abramowitz, Elad Asher, Jamal Jafari, Vladimir Shlyakhover, Doron Zahger, Moti Haim, Chaim Yosefy   +13 more
wiley   +1 more source

Novel three‐dimensional ECG algorithm for reliable screening for cardiac amyloidosis

ESC Heart Failure, EarlyView.
The present manuscript describes the derivation and validation of an algorithm for screening of cardiac amyloidosis using 3‐dimensional ECG. The algorithm is based on a ECG vector loop, acquired over the duration of 15 seconds using 4 electrodes. With this easy to perform method, we describe a high diagnostic accuracy for the detection of cardiac ...
Amir A. Mahabadi, Jan Knobeloch, Viktoria Backmann, Lars Michel, Markus S. Anker, Reza Wakili, Christian Fach, Stefan D. Anker, Tienush Rassaf   +8 more
wiley   +1 more source