Results 61 to 70 of about 1,622,247 (397)

Risk Stratification for Sudden Cardiac Death In Patients With Non-ischemic Dilated Cardiomyopathy [PDF]

, 2005
Non ischemic dilated cardiomyopathy (NIDCM) is a disorder of myocardium. It has varying etiologies. Albeit the varying etiologies of this heart muscle disorder, it presents with symptoms of heart failure, and rarely as sudden cardiac death (SCD ...
Ghosh, Joydeep, Greenberg, Yisachar, Shekha, Karthik, Thekkoott, Deepak   +3 more
core   +1 more source

Resolving Artifacts in Voltage‐Clamp Experiments with Computational Modeling: An Application to Fast Sodium Current Recordings

Advanced Science, EarlyView.
Patch‐clamp experiments are fundamental to the measurement and understanding of ion currents that underlie physiological functions from neural activity to muscle contraction. Via a mathematical model of the experimental apparatus, this article highlights how artifact effects can be as large as some reported mutation and drug effects, and enables ...
Chon Lok Lei, Alexander P. Clark, Michael Clerx, Siyu Wei, Meye Bloothooft, Teun P. de Boer, David J. Christini, Trine Krogh‐Madsen, Gary R. Mirams   +8 more
wiley   +1 more source

Evaluation of photogrammetry for medical application in cardiology

Frontiers in Bioengineering and Biotechnology, 2023
Background: In the field of medicine, photogrammetry has played for long time a marginal role due to the significant amount of work required that made it impractical for an extended medical use.
Giacomo Talevi, Luigi Pannone, Cinzia Monaco, Edoardo Bori, Ida Anna Cappello, Mara Candelari, Manon Wyns, Robbert Ramak, Mark La Meir, Ali Gharaviri, Gian Battista Chierchia, Bernardo Innocenti, Carlo de Asmundis   +12 more
doaj   +1 more source

PFKM‐Driven Lactate Overproduction Promotes Atrial Fibrillation via Triggering Cardiac Fibroblasts Histone Lactylation

Advanced Science, EarlyView.
The upregulation of PFKM activates glycolysis, thereby enhancing lactate production in atrial tissue. Atrial lactate accumulation promotes global lactylation and H3K18 lactylation in atrial fibroblasts. P300‐mediated H3K18 lactylation up‐regulates TGF‐β1 transcription, leading to fibroblast activation and thereby contributing to atrial fibrosis.
Ning Fang, Ning Zhang, Xiaohui Jiang, Sen Yan, Zhiqi Wang, Qianhui Gao, Mingcheng Xu, Lin Mu, Xiaoming Li, Jiuling Chen, Song Zhang, Yu Duan, Fengxiang Yun, Luyifei Li, Yun Zhang, Yongtai Gong   +15 more
wiley   +1 more source

Left Bundle Branch Pacing in Transthyretin Cardiac Amyloidosis and Alternating Bundle Branch Block

JACC: Case Reports, 2020
Progressive conduction system disease affects patients with transthyretin cardiac amyloidosis, often requiring permanent pacing as the His-Purkinje system is affected. We present a case of left bundle branch pacing in a patient with transthyretin cardiac
Taha Ahmed, MD, Samra Haroon Lodhi, MBBS, Hassan Lak, MD, Jae Lee, MD, Mazen Hanna, MD, Roy Chung, MD   +5 more
doaj  

Acute and one year outcome of premature ventricular contraction ablation guided by contact force and automated pacemapping software

Journal of Arrhythmia, 2019
Background Radiofrequency (RF) ablation is a well‐established approach to treat premature ventricular contractions (PVC) and is associated with good outcomes.
Lucio Capulzini, Pasquale Vergara, Giacomo Mugnai, Francesca Salghetti, Juan Pablo Abugattas, Said El Bouchaibi, Saverio Iacopino, Juan Sieira, Hugo Enriquez Coutiño, Erwin Ströker, Pedro Brugada, Gianbattista Chierchia, Carlo deAsmundis   +12 more
doaj   +1 more source

Magnetic Resonance Imaging in patients with ICDs and Pacemakers [PDF]

, 2005
Magnetic resonance (MR) imaging has unparalleled soft-tissue imaging capabilities. The presence of devices such as pacemakers and implantable cardioverter/defibrillators (ICDs), however, is historically considered a contraindication to MR imaging.
Ariel, Roguin, Prashant, Nair
core  

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy.

European Heart Journal, 2021
M. Glikson, J. C. Nielsen, M. Kronborg, Y. Michowitz, Angelo Auricchio, I. Barbash, J. Barrabés, G. Boriani, F. Braunschweig, Michele Brignole, H. Burri, A. Coats, J. Deharo, V. Delgado, G. Diller, Carsten W Israel, Andre Keren, R. Knops, D. Kotecha, C. Leclercq, B. Merkely, Christoph Starck, I. Thylén, J. Tolosana   +23 more
semanticscholar   +2 more sources

Mechanisms of Vein of Marshall-Related Tachyarrhythmias and the Impact of Ethanol Infusion

Reviews in Cardiovascular Medicine
The Ligament of Marshall (LOM) is a remnant of the embryonic sinus venosus and the left cardinal vein, containing a combination of fat, fibrous tissue, blood vessels, muscle bundles, nerve fibers, and ganglia.
Masateru Takigawa, Claire Martin, Pierre Jaïs   +2 more
doaj   +1 more source