Results 311 to 320 of about 160,558 (349)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra   +8 more
wiley   +1 more source

The Role of Epicardial Adipose Tissue in Acute Coronary Syndromes, Post-Infarct Remodeling and Cardiac Regeneration. [PDF]

open access: yesInt J Mol Sci
Krauz K   +6 more
europepmc   +1 more source

flt1 inactivation promotes zebrafish cardiac regeneration by enhancing endothelial activity and limiting the fibrotic response.

open access: yesDevelopment
Wang ZY   +10 more
europepmc   +1 more source
Some of the next articles are maybe not open access.

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Cardiac Regeneration in Children

Pediatric Cardiology, 2015
Very young mammals have an impressive cardiac regeneration capacity. In contrast, cardiac regeneration is very limited in adult humans. The hearts of young children have a higher regenerative capacity compared with adults, as, for example, seen after surgical correction of an anomalous left coronary artery arising from the pulmonary artery or in ...
Stefan, Rupp, Dietmar, Schranz
openaire   +2 more sources

microRNA and Cardiac Regeneration

2015
Heart diseases are a very common health problem in developed as well as developing countries. In particular, ischemic heart disease and heart failure represent a plague for the patients and for the society. Loss of cardiac tissue after myocardial infarction or dysfunctioning tissue in nonischemic cardiomyopathies may result in cardiac failure.
GNECCHI, MASSIMILIANO   +2 more
openaire   +3 more sources

Cardiac regeneration therapy: connections to cardiac physiology

American Journal of Physiology-Heart and Circulatory Physiology, 2011
Without heart transplantation, a large number of patients with failing hearts worldwide face poor outcomes. By means of cardiomyocyte regeneration, cardiac regeneration therapy is emerging with great promise as a means for restoring loss of cardiac function.
Naofumi, Takehara, Hiroaki, Matsubara
openaire   +2 more sources

Experimental models for cardiac regeneration

Nature Clinical Practice Cardiovascular Medicine, 2006
Simple ex vivo or in vitro models are most useful for testing putative cell therapy protocols, as they allow quick and controlled screening of variants and possible improvements. We discuss here three different models: coculture of precursors of human bone marrow cells (BMCs) with mouse heart slices bearing a cryogenic lesion; coculture of human BMCs ...
Ana, Sánchez   +6 more
openaire   +2 more sources

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