Results 21 to 30 of about 244,717 (262)

Vagal nerve stimulation therapy: what is being stimulated? [PDF]

PLoS ONE, 2014
Vagal nerve stimulation in cardiac therapy involves delivering electrical current to the vagal sympathetic complex in patients experiencing heart failure. The therapy has shown promise but the mechanisms by which any benefit accrues is not understood. In
Guy Kember, Jeffrey L Ardell, John A Armour, Mair Zamir   +3 more
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Electrical Stimulation Promotes Cardiac Differentiation of Human Induced Pluripotent Stem Cells

Stem Cells International, 2016
Background. Human induced pluripotent stem cells (iPSCs) are an attractive source of cardiomyocytes for cardiac repair and regeneration. In this study, we aim to determine whether acute electrical stimulation of human iPSCs can promote their ...
Damián Hernández, Rodney Millard, Priyadharshini Sivakumaran, Raymond C. B. Wong, Duncan E. Crombie, Alex W. Hewitt, Helena Liang, Sandy S. C. Hung, Alice Pébay, Robert K. Shepherd, Gregory J. Dusting, Shiang Y. Lim   +11 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Right ventricular bifocal stimulation in the treatment of dilated cardiomyopathy with heart failure

Arquivos Brasileiros de Cardiologia, 1999
OBJECTIVE: To describe a new more efficient method of endocardial cardiac stimulation, which produces a narrower QRS without using the coronary sinus or cardiac veins.
José Carlos Pachón Mateos, Remy Nelson Albornoz, Enrique Indalécio Pachón Mateos, Vera Márcia Gimenez, Juán Carlos Pachón Mateos, Maria Zélia Cunha Pachón, Eusebio Ramos dos Santos Fº, Paulo de Tarso Jorge Medeiros, Marco Aurélio Dias da Silva, Paulo Paredes Paulista, José Eduardo Moraes Rêgo Sousa, Adib Domingos Jatene   +11 more
doaj   +1 more source

Toll-like receptor 9 mediated responses in cardiac fibroblasts. [PDF]

PLoS ONE, 2014
Altered cardiac Toll-like receptor 9 (TLR9) signaling is important in several experimental cardiovascular disorders. These studies have predominantly focused on cardiac myocytes or the heart as a whole.
Ingrid Kristine Ohm, Katrine Alfsnes, Maria Belland Olsen, Trine Ranheim, Øystein Sandanger, Tuva Børresdatter Dahl, Pål Aukrust, Alexandra Vanessa Finsen, Arne Yndestad, Leif Erik Vinge   +9 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Cardiac myosin binding protein C, adrenergic stimulation and cardiac contractility

SA Heart Journal, 2017
Myosin binding protein C remained a perplexing although integral component of the sarcomeric thick filament until the discovery that genetic defects in its corresponding gene is a frequent cause of hypertrophic cardiomyopathy. Basic science investigation
Amsha Ramburan, Lundi Korkie, Johanna C. Moolman-Smook   +2 more
doaj   +1 more source

Pseudoanginal chest pain associated with vagal nerve stimulation: a case report

BMC Neurology, 2020
Background Vagal nerve stimulation (VNS) can be an effective therapy for patients with epilepsy refractory to anti-epileptic drugs or intracranial surgery.
James B. Nichols, Abigail P. McCallum, Nicolas K. Khattar, George Z. Wei, Rakesh Gopinathannair, Haring J. W. Nauta, Joseph S. Neimat   +6 more
doaj   +1 more source

Photovoltaic Stimulation Induces Overdrive Suppression in Embryonic Chicken Cardiomyocytes

Current Directions in Biomedical Engineering, 2023
In this study, we employed calcium imaging to investigate the dynamics of intracellular calcium levels in embryonic chicken cardiomyocytes upon extracellular, optoelectronic stimulation.
Polz Mathias, Ziesel Daniel, Shrestha Niroj, Pelzmann Brigitte, Lang Petra, Scherübel Susanne, Üçal Muammer, Kornmüller Karin, Schröttner Jörg, Đerek Vedran, Opančar Aleksandar, Głowacki Eric Daniel, Baumgartner Christian, Rienmüller Theresa   +13 more
doaj   +1 more source