Results 1 to 10 of about 73,816 (117)

Influenza-associated cardiac injury: a disease of the cardiac conduction system? [PDF]

Cardiovasc Res, 2021
Protonotarios A, Marelli-Berg F.
europepmc   +5 more sources

Development and Function of the Cardiac Conduction System in Health and Disease [PDF]

Journal of Cardiovascular Development and Disease, 2017
The generation and propagation of the cardiac impulse is the central function of the cardiac conduction system (CCS). Impulse initiation occurs in nodal tissues that have high levels of automaticity, but slow conduction properties. Rapid impulse propagation is a feature of the ventricular conduction system, which is essential for synchronized ...
David S. Park, Glenn I. Fishman
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Conduction System Pacing Versus Conventional Cardiac Resynchronization Therapy in Congenital Heart Disease [PDF]

JACC: Clinical Electrophysiology, 2023
Dyssynchrony-associated left ventricular systolic dysfunction is a major contributor to heart failure in congenital heart disease (CHD). Although conventional cardiac resynchronization therapy (CRT) has shown benefit, the comparative efficacy of cardiac conduction system pacing (CSP) is unknown.The purpose of this study was compare the clinical ...
Moore, Jeremy P, de Groot, Natasja M S, O'Connor, Matthew, Cortez, Daniel, Su, Jonathan, Burrows, Austin, Shannon, Kevin M, O'Leary, Edward T, Shah, Maully, Khairy, Paul, Atallah, Joseph, Wong, Tom, Lloyd, Michael S, Taverne, Yannick J H J, Dubin, Anne M, Nielsen, Jens C; id_orcid 0000-0001-9414-1653, Evertz, Reinder, Czosek, Richard J, Madhavan, Malini, Chang, Philip M, Aydin, Alper, Cano, Óscar   +21 more
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Rare SCN10A variants associated with cardiac conduction system diseases [PDF]

European Heart Journal, 2020
Abstract Background The genetic bases of cardiac conduction-system disease (CCSD) range from ion channelopathies to mutations in many other genes. Genome-wide association studies have shown common variants in SCN10A influence cardiac conduction.
K Hayashi, N Fujino, H Furusho, S Usui, K Sakata, T Kato, T Tsuda, S Niwa, K Takeuchi, M Kawashiri, M Takamura   +10 more
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Impact of functional studies on exome sequence variant interpretation in early-onset cardiac conduction system diseases [PDF]

Cardiovascular Research, 2020
Abstract Aims The genetic cause of cardiac conduction system disease (CCSD) has not been fully elucidated. Whole-exome sequencing (WES) can detect various genetic variants; however, the identification of pathogenic variants remains a challenge.
Kenshi Hayashi, Ryota Teramoto, Akihiro Nomura, Yoshihiro Asano, Manu Beerens, Yasutaka Kurata, Isao Kobayashi, Noboru Fujino, Hiroshi Furusho, Kenji Sakata, Kenji Onoue, David Y Chiang, Tuomas O Kiviniemi, Eva Buys, Patrick Sips, Micah L Burch, Yanbin Zhao, Amy E Kelly, Masanobu Namura, Yoshihito Kita, Taketsugu Tsuchiya, Bunji Kaku, Kotaro Oe, Yuko Takeda, Tetsuo Konno, Masaru Inoue, Takashi Fujita, Takeshi Kato, Akira Funada, Hayato Tada, Akihiko Hodatsu, Chiaki Nakanishi, Yuichiro Sakamoto, Toyonobu Tsuda, Yoji Nagata, Yoshihiro Tanaka, Hirofumi Okada, Keisuke Usuda, Shihe Cui, Yoshihiko Saito, Calum A MacRae, Seiji Takashima, Masakazu Yamagishi, Masa-aki Kawashiri, Masayuki Takamura   +44 more
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Cardiac hypertrophy, accessory pathway, and conduction system disease in an adolescent: the PRKAG2 cardiac syndrome.

Journal of the American College of Cardiology, 2013
We present the case of PRKAG2 cardiac syndrome, a rare autosomal-dominant genetic disease characterized by peculiar clinical and electrophysiological abnormalities. We clearly show through the images the peculiar clinical features that should raise suspicion of a mutant PRKAG2 gene. Indeed, together with an accurate clinical and instrumental evaluation,
Fabris E, Brun F, Porto AG, Losurdo P, Vitali Serdoz L, Zecchin M, Severini GM, Mestroni L, Di Chiara A, SINAGRA, GIANFRANCO   +9 more
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Rapidly Progressive Cardiac Manifestation of Behçet's Disease Involving Conduction System and Aortic Valve [PDF]

Journal of Cardiovascular Ultrasound, 2011
Cardiac conduction system impairment is a rare clinical manifestation of Behçet's disease. We report a patient who showed 1st degree atrioventricular block at first presentation, and showed aggravated finding of 3rd degree atrioventricular block on five months later.
Yu, Jin Sok, Cho, Eun Joo, Ji, Eun Hye, Kwon, Hee Sun, Kim, Jin Seok, Choi, Kyu Young, Kwon, Beom June, Kim, Dong Bin, Jang, Seong Won, Kim, Jae Hyung   +9 more
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Left bundle branch–optimized cardiac resynchronization therapy: Pursuing the optimal resynchronization in severe (distal) conduction system disease [PDF]

HeartRhythm Case Reports, 2023
Contains fulltext : 294265.pdf (Publisher’s version ) (Open Access)
Jesse Rijks, Justin Luermans, Kevin Vernooy   +2 more
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Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease [PDF]

Journal of Molecular and Cellular Cardiology, 2008
Mutations in the lamin A/C (LMNA) gene, which encodes nuclear membrane proteins, cause a variety of human conditions including dilated cardiomyopathy (DCM) with associated cardiac conduction system disease. To investigate mechanisms responsible for electrophysiologic and myocardial phenotypes caused by dominant human LMNA mutations, we performed ...
Cordula M, Wolf, Libin, Wang, Ronny, Alcalai, Anne, Pizard, Patrick G, Burgon, Ferhaan, Ahmad, Megan, Sherwood, Dorothy M, Branco, Hiroko, Wakimoto, Glenn I, Fishman, Vincent, See, Colin L, Stewart, David A, Conner, Charles I, Berul, Christine E, Seidman, J G, Seidman   +15 more
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Limited effects of long-term enzyme replacement therapy on the cardiac conduction system in Fabry disease [PDF]

Journal of Cardiology Cases, 2018
The long-term effects of enzyme replacement therapy (ERT) on cardiac function and the conduction system in Fabry disease are not clearly understood. We report a case of a 48-year-old man with non-classical Fabry disease treated with ERT for 11 years.
Tomoya, Kaneda, Masahiro, Takeda, Tetsuro, Suematsu, Ryusuke, Yamamoto, Mutsuko, Takata, Toshinori, Higashikata, Hidekazu, Ino, Akihiko, Tsujibata, Kenshi, Hayashi, Noboru, Fujino, Masa-Aki, Kawashiri   +10 more
openaire   +2 more sources