Results 1 to 10 of about 70,504 (293)

Development and Function of the Cardiac Conduction System in Health and Disease [PDF]

Journal of Cardiovascular Development and Disease, 2017
The generation and propagation of the cardiac impulse is the central function of the cardiac conduction system (CCS). Impulse initiation occurs in nodal tissues that have high levels of automaticity, but slow conduction properties.
David S. Park, Glenn I. Fishman
doaj   +6 more sources

Prevalence of cardiac fibrosis and infiltrative cardiomyopathy in patients with advanced conduction system disease

Journal of Arrhythmia
Background Conduction system disease may represent an early manifestation of underlying structural heart disease, including infiltrative disorders.
Jeremy William, Haider Muthana, Joseph Hogarty, Andrew Taylor, James L. Hare, Justin Mariani, Hitesh Patel, Geoff Wong, Dion Stub, David M. Kaye, Sandeep Prabhu, Peter M. Kistler, Aleksandr Voskoboinik   +12 more
doaj   +4 more sources

Influenza-associated cardiac injury: a disease of the cardiac conduction system? [PDF]

Cardiovasc Res, 2021
This editorial refers to ‘Human influenza A virus causes myocardial and cardiac-specific conduction system infections associated with early inflammation and premature death’, by D. Filgueiras-Rama et al., pp.
Protonotarios A, Marelli-Berg F.
europepmc   +7 more sources

Is there an association between Fahr′s disease and cardiac conduction system disease?: A case report

Journal of Research in Medical Sciences, 2012
Background: Fahr′s disease is a rare neurodegenerative disorder of unknown cause characterized by idiopathic basal ganglia calcification that is associated with neuropsychiatric and cognitive impairment.
Prashanth Panduranga, Kadhim Sulaiman
doaj   +3 more sources

Zebrafish Models in Therapeutic Research of Cardiac Conduction Disease

Frontiers in Cell and Developmental Biology, 2021
Malfunction in the cardiac conduction system (CCS) due to congenital anomalies or diseases can cause cardiac conduction disease (CCD), which results in disturbances in cardiac rhythm, leading to syncope and even sudden cardiac death.
Rui Gao, Jie Ren
doaj   +3 more sources

Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease [PDF]

Journal of Molecular and Cellular Cardiology, 2008
Mutations in the lamin A/C (LMNA) gene, which encodes nuclear membrane proteins, cause a variety of human conditions including dilated cardiomyopathy (DCM) with associated cardiac conduction system disease. To investigate mechanisms responsible for electrophysiologic and myocardial phenotypes caused by dominant human LMNA mutations, we performed ...
Cordula M Wolf, Ronny Alcalai, Anne Pizard   +2 more
exaly   +3 more sources

Incidence of carditis and predictors of pacemaker implantation in patients hospitalized with Lyme disease

PLoS ONE, 2021
Background Lyme carditis, defined as direct infection of cardiac tissue by Borrelia bacteria, affects up to 10% of patients with Lyme disease. The most frequently reported clinical manifestation of Lyme carditis is cardiac conduction system disease.
Uwajachukwumma A. Uzomah, Guy Rozen, Seyed Mohammadreza Hosseini, Ayman Shaqdan, Pablo A. Ledesma, Xuejing Yu, Pegah Khaloo, Jennifer Galvin, Leon M. Ptaszek, Jeremy N. Ruskin   +9 more
doaj   +2 more sources

Regulation of Cardiac Conduction and Arrhythmias by Ankyrin/Spectrin-Based Macromolecular Complexes

Journal of Cardiovascular Development and Disease, 2021
The cardiac conduction system is an extended network of excitable tissue tasked with generation and propagation of electrical impulses to signal coordinated contraction of the heart.
Drew Nassal, Jane Yu, Dennison Min, Cemantha Lane, Rebecca Shaheen, Daniel Gratz, Thomas J. Hund   +6 more
doaj   +1 more source

Conduction System Pacing Versus Conventional Cardiac Resynchronization Therapy in Congenital Heart Disease [PDF]

JACC: Clinical Electrophysiology, 2023
Dyssynchrony-associated left ventricular systolic dysfunction is a major contributor to heart failure in congenital heart disease (CHD). Although conventional cardiac resynchronization therapy (CRT) has shown benefit, the comparative efficacy of cardiac conduction system pacing (CSP) is unknown.The purpose of this study was compare the clinical ...
Moore, Jeremy P, de Groot, Natasja M S, O'Connor, Matthew, Cortez, Daniel, Su, Jonathan, Burrows, Austin, Shannon, Kevin M, O'Leary, Edward T, Shah, Maully, Khairy, Paul, Atallah, Joseph, Wong, Tom, Lloyd, Michael S, Taverne, Yannick J H J, Dubin, Anne M, Nielsen, Jens C; id_orcid 0000-0001-9414-1653, Evertz, Reinder, Czosek, Richard J, Madhavan, Malini, Chang, Philip M, Aydin, Alper, Cano, Óscar   +21 more
openaire   +4 more sources

Advances in Physiological Cardiac Stimulation

Journal of Cardiac Arrhythmias, 2021
Advances in cardiac stimulation demonstrate that bradyarrhythmia treatments go beyond heart rate control. The concern with the ventricular stimulation site and, consequently, with the maintenance of intraventricular synchrony has become routine in most ...
Gustavo Galli Reis, Andres Di Leoni Ferrari, Gustavo Chiari Cabral, Guilherme Ferreira Gazzoni, Luis Manuel Ley, Jessica Caroline Feltrin Willes, Flavio Vinicius Costa Ferreira, Laura Orlandini Lodi   +7 more
doaj   +4 more sources