Results 21 to 30 of about 190,151,534 (289)
Direct reprogramming of cardiomyocytes into cardiac Purkinje-like cells
iScience, 2022 Summary: Currently, there are no treatments that ameliorate cardiac cell death, the underlying basis of cardiovascular disease. An unexplored cell type in cardiac regeneration is cardiac Purkinje cells; specialized cells from the cardiac conduction ...Nicole Prodan, Faheem Ershad, Arfaxad Reyes-Alcaraz, Luge Li, Brandon Mistretta, Lei Gonzalez, Zhoulyu Rao, Cunjiang Yu, Preethi H. Gunaratne, Na Li, Robert J. Schwartz, Bradley K. McConnell +11 moredoaj +1 more sourceEngineering a conduction-consistent cardiac patch with rGO/PLCL electrospun nanofibrous membranes and human iPSC-derived cardiomyocytes
Frontiers in Bioengineering and Biotechnology, 2023 The healthy human heart has special directional arrangement of cardiomyocytes and a unique electrical conduction system, which is critical for the maintenance of effective contractions.Yao Tan, Ying Chen, Tingting Lu, Nevin Witman, Bingqian Yan, Yiqi Gong, Xuefeng Ai, Li Yang, Li Yang, Minglu Liu, Runjiao Luo, Huijing Wang, Stefano Ministrini, Stefano Ministrini, Wei Dong, Wei Wang, Wei Fu, Wei Fu +17 moredoaj +1 more sourceDesmin variants: Trigger for cardiac arrhythmias?
Frontiers in Cell and Developmental Biology, 2022 Desmin (DES) is a classical type III intermediate filament protein encoded by the DES gene. Desmin is abundantly expressed in cardiac, skeletal, and smooth muscle cells.Wei Su, Wei Su, Stan W. van Wijk, Stan W. van Wijk, Bianca J. J. M. Brundel, Bianca J. J. M. Brundel +5 moredoaj +1 more sourceIdentification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders [PDF]
, 2011 Elevated resting heart rate is associated with greater risk of cardiovascular disease and mortality. In a 2-stage meta-analysis of genome-wide association studies in up to 181,171 individuals, we identified 14 new loci associated with heart rate and ...Kooner, A.S., Cusi, D., Munroe, P., Laiho, Päivi, P. Elliott, D. Absher, Assimes, Themistocles L., Ingelsson, E., C. Wijmenga, Sibon, O.C., Sanna, Serena, Rossin EJ, Pfeufer, Arne, Anneli Pouta, van der Schouw, Y.T., Qi, L., Knowles, JW, Hicks, Andrew A, D. J. Hunter, Groop L, van der Klauw, MM (Melanie), Nelis, M, Albert, Christine M., Olsen, J.V., Sibon, Ody C M, Mari Nelis, Chip Stewart, Toshiko Tanaka, Kim, Young Jin, Peters, Annette, van Gilst, W., Whitfield, J., A. U. Jackson, Kim, Y. J., Poulter, Neil R, Smith, AV, Holewijn, S, Steven A McCarroll, Arnar, D.O., Kathryn A Miller, McArdle WL, Scott RA, D. O. Arnar, Navarro, Pau, M. R. Markus, Antti Jula, Qi, Lu, Qi L, Uitterlinden, André G, Tarasov, K., Forouhi, Nita G., O'Donnell, C., W. L. Caulfield, Jarvelin, M., Stefansson, K, Chambers, John C, Whitfield, JB, Smith AV, O'Donnell, CJ, M. den Heijer, Waite L, Gary Curhan, Robert A Scott, K. L. Lunetta, Montgomery, G.W., Igl, W., Draisma HH, Sever, Peter S, Knowles, J., Tarasov, KV, Quertermous, T., Heckbert, Susan R., J. C. Bis N. Bouatia Naji, Hsueh, Wen-Chi, Milani, L., Hingorani A, Munroe, PB, de Geus, E.J., de Bakker, Paul I. W., M. Chung, Handsaker, Robert E, Qi, L, Thompson, J., de Geus, Eco J C, Eijgelsheim, Mark, Smith, GD, Evans DM, Handsaker, Robert E., S. H. Wild, Claude Bouchard, Strachan, David P., Ong, KK, Smith, G., Dan E Arking, Johnson, T, Jordan T Shin, M. Kumari, Jula A, Shuldiner AR, Femke Hoogstra-Berends, Jarvelin MR, Alonso, Alvaro, Kerr, KF, R. N. Luben, Peter S Chines, et al., Joshua W Knowles, van Gilst, WH, Quertermous T, Peal, D.S., Ketkar S, Rizzi F, Olsen, Jesper V., Nieminen MS, de Boer, Rudolf A., Loic Yengo, Johnson T, Y. T. van der Schouw, Zhang, W., P. Navarro, Raitakari, Olli T., Vitart, Veronique, van der Schouw, Y., Westra, HJ, Iribarren, Carlos, Ody C M Sibon, Laiho, Paeivi, Martin, Nicholas G, A. Johansson, Jolanda M A Boer, Kähönen, M., C. Langenberg, Ketkar, S, Iacoviello, Licia, Neil R Poulter, van der Schouw, YT, Hadley, D., Evelin Mihailov, Montasser ME, E. J. de Geus, Thompson, JR, Pourcain, Beate St., Westra, H., B. St Pourcain, Ong, K.K., Gudbjartsson, Daniel, Weedon, Michael N., Wareham, N.J., N. C. Onland Moret, Scott, Robert A., Barlassina C, Ulf Gyllensten, van der Schouw YT, Visscher, P., Pourcain, BS, Loos R.J., E. B. Rimm, Erdmann, Jeanette, Tardif JC, Salo, P, Alonso A, van Veldhuisen DJ, B. A. Oostra, E. Widen, Pedersen, Nancy L., Tim D Spector, Verschuren, W. M. Monique, van Gilst, Wiek H, Zhang, WH, Laiho, P, Willer, Cristen, Pedersen, Nancy L, Visscher, PM, Brage, S., Hicks, Andrew A., Lynch SN, Cornelis MC, Verschuren, W.M.M., Rankinen, T, Jackson, A.U., Sever, P.S., Annette Peters, Wilson, James F, Huikuri, Heikki V, den Hoed, M, Kemp, J.P., Rankinen T, Iacoviello, L, S. Bandinelli, Hofman A, Federica Rizzi, Mateo Leach I, de Geus, EJC, Daniel Gudbjartsson, Erdmann, J, Leusink M, Hottenga, J.J., Peter M Visscher, Albert V Smith, Hicks, A.A., Beckmann, Jacques S, Weedon MN, Alvaro Alonso, H. J. Westra, Polasek, Ozren, Brage, S, Thorsteinsdottir, U, Ruth J F Loos, Jarvelin, MR, Elliott P, Miller, Kathryn A., van Duijn, Cornelia M., W. C. Hsueh, Sehmi, J.S., Müller-Nurasyid, M., Lakatta, Edward G., Shields DC, Medland, S.E., Virtamo J, Jackson, Anne U, Newton-Cheh, C, Snieder, Harold, A. S. Havulinna, Huikuri HV, Elizabeth J Rossin, Tuomilehto J, Zhao, JH, D. Kuh, Kivimaki, M., Tardif, J.C., Yang, L., Pramstaller, PP, O'Reilly PF, Mihailov E, Tarasov, Kirill V, Smith, A., Vollenweider, P, Wilmar Igl, Knowles JW, Tarasov, K.V., Marcello R P Markus, Brundel, Bianca J J M, Stolk, Ronald P, Singleton AB, Nolte, I., Visscher, Peter M., Rao DC, Elisabeth Widen, Elliott, P., Fuchsberger, C., M. Dörr, L. Qi, Pramstaller, P., Cornelis, Marilyn C, Salo, P., Zhao, J., Rankinen, Tuomo, Kim, YJ, Tanaka, T, Marjo-Riitta Jarvelin, Handsaker, R.E., Lakatta, E., Jamshidi, Yalda, Psaty, Bruce M., Lynch, S.N., Wong, QN, Khaw, K., Jan A Kors, Kiemeney, L.A.L.M., Mihailov, Evelin, Mitchell, Braxton D., T. Rankinen, Tuomilehto, J., Sarah E Medland, N. J. Timpson, U. Thorsteinsdottir, Morrison, Alanna C, Pedro Marques-Vidal, Milan, David J, Kim, Y., Dirk J van Veldhuisen, Serena Sanna, Lakatta, EG, Holm H, P. A. Lind, E. Ingelsson, Caulfield, W., Shin, Jordan T., CHARGE AF Consortium, den Hoed M, M. E. Montasser, Anne B Newman, Richard A Kronmal, Timpson NJ, Markus, M., Hartikainen, A., Dorret I Boomsma, Segrè AV, Bochud, M., W. Wheeler, Wheeler, W., Wong, Q., Kari Stefansson, Bis JC, Khaw, KT, Hartikainen, AL, Rimm, Eric B, Peal DS, Hu, Frank B., Jensen, MK, Rotter JI, Mihailov, E., Chines, Peter S., Pedersen, N., St Pourcain, Beate, Poulter, N.R., Smith, G.D., Fischer, K (Kirsten), Absher D, Vilmundur Gudnason, Rao, Dabeeru C., Thompson, J.R., Jensen, M., Medland, Sarah E., Felix, Stephan B, Bis, J.C., Wilson, J.F., Samani, N.J., Kronmal, Richard A, Gerjan Navis, T. Johnson, Raitakari, O., Pedersen, NL, van Duijn CM, D. Gudbjartsson, Samani NJ, Olli T Raitakari, Soranzo, N., E. Mihailov, Waeber, G., Zoltán Kutalik, Pouta, A., Widen, Elisabeth, Stacey N Lynch, Montasser, ME, Raitakari, OT, Shin JT, Feitosa MF, Isaacs, A., Hunter DJ, S. Padmanabhan, Segrè, A.V., Kiemeney, L.A., St. Pourcain, B., Hwang, S.J., Global BPgen Consortium, Wilson, James F; id_orcid, O'Reilly, P.F., Gabrielle Boucher, Kooner JS, Montasser, M., Navarro P, Kuh, D, Young Jin Kim, Ring, S., J. Virtamo, Jerome I Rotter, Brundel, B.J., Morrison AC, Lakatta, Edward G, de Geus, E.J.C., Willemsen, G.; id_orcid, A. Alonso, Rimm, E., Chambers, J.C., Khaw, Kay-Tee, Sever, P., Navarro, P., Montgomery, Grant W, Stricker BH, Ring, SM, Hayward C, Forouhi NG, Holm, H, van der Schouw, Yvonne T., Hoed, M. den, Samani, Nilesh J, Gudbjartsson, D, Kristiansson, Kati, P. M. Visscher, Boomsma, Dorret I., J. S. Sehmi, McArdle, W.L., Sever, PS, A. G. Uitterlinden, Hsueh, W.C., Handsaker, R., Fischer K, Ladenvall C, Michael N Weedon, Hayward, Caroline, Lynch, SN, Lehtimäki T, Kerr, K., Erdmann J, Albert Hofman, Salo P, Igl, Wilmar, Yang, Jiaqi, Scott, R., Boucher, G, T. Esko, Arnar, DO, CARDIoGRAM Consortium, Lynch, S., Handsaker, RE, Scott, RA, Lindsay Waite, Hicks, A., van Veldhuisen, D.J., Müller-Nurasyid, Martina, Rimm, EB, David M Evans, Albanes D, Boucher G, Arnar, D., Kooner, JS, J. A. Kors, Kiemeney, Lambertus A, K. Fischer, Hicks AA, Hicks, AA, Franke, L., Junttila J, Lakatta, E.G., Cusi, D, Weedon, MN, Stanton, A.V., Oostra, B.A., M. M. van der Klauw, A. C. Morrison, Patrick T Ellinor, L. Groop, Pourcain, B. St, Jamshidi Y, Harmen H M Draisma, Yang J, Sibon, Ody C. M.; id_orcid, Graaf, J. de, Michael Boehnke, Westra, H.J., Spector, T.D., Loos, R.J.F., Forouhi, N., G. W. Montgomery, Lynch, Stacey N, Dina, Christian, Wilson, JF, Forouhi, NG, Waeber, G, Jesper V Olsen, Waite, Lindsay, Bouchard, C, de Geus, Eco J. C., Holm, H., Kim, Y.J., Wilson, J., I. B. Borecki, Dawood Darbar, Absher, D., Sehmi, Jaban S., A. B. Newman, Sandosh Padmanabhan, Leif Groop, Weedon, M., Shields, DC, Froguel, P., K. A. Miller, Braxton D Mitchell, Smith GD, David S Peal, Timpson, N.J., Ulf Ekelund, de Bakker, P., Kooner AS, Shields, D., A. Isaacs, Froguel, P, Lynch, Stacey N., Hoogstra-Berends, F., V. Gudnason, Harris, Tamara B, Mark Walker, Boer, J.M.A., Robert E Handsaker, Claes Ladenvall, Boehnke, M, Groop, L, Sanna, S, Isomaa, B., Walker M, de Bakker, P.I.W., Nolte IM, de Geus EJ, Kemp, John P, Newman, Anne B, Raitakari OT, Paul I W de Bakker, Hu, F.B., Hottenga, J.-J., Ellinor, Patrick T., Langenberg, C, Borecki, Ingrid B., Evans, D., M. N. Weedon, Bochud, Murielle, Marques-Vidal, P, Huikuri, HV, Leusink, Maarten, Albert, C.M., Lind, Lars, Sehmi, Jaban S, A. L. Hartikainen, Stefan Kääb, Hoogstra-Berends, Femke, Lunetta, Kathryn L., Milan, David J., Navarro, P, Peal, David S, Evans, DM, Heckbert, Susan R, Tamara B Harris, Ronald P Stolk, Eriksson, Johan, J. Junttila, F. B. Hu FB, Kanon, B, Chanock, Stephen J, Gérard Waeber, Huikuri, H., Wong, A., Wen-Chi Hsueh, Yengo, L., Isomaa, B, Lundby, A., Chines, P.S., Medland SE, John D Rioux, Vandenput, Liesbeth, D. J. van Veldhuisen, I. Rudan, Melanie M van der Klauw, Jensen MK, Draisma, H., Stolk, RP (Ronald), Havulinna, A.S., Nolte, IM (Ilja), Martin, NG, J. P. Kemp, S. N. Lynch, Johnson, T., van Duijn, C., Salomaa, V, Jian Yang, Yang, Jian, J. R. O'Connell, Y. Liu, Kanon B, Martin, N., J. T. Shin, Shuldiner, A.R., Padmanabhan S, Jaspal S Kooner, Liu Y, Sharp, S., Sharp S, Hsueh WC, C. M. Albert, Nicola Glorioso, Ring, Susan M, Marja-Liisa L Lokki, Milan, D.J., Isomaa, Bo, Caulfield, W.L., O'Donnell CJ, Snieder, H, Peter S Sever, Nieminen, Markku S, B. Kanon, M. J. Go, Hunter, David J, Päivi Laiho, W. Igl, Hsueh, W.-C., Chines, Peter S, Ellinor, Patrick T, Esko, T, Rotter, Jerome I, Nicholas J Wareham, Claudia Langenberg, Ekelund, U., Whitfield, John B, Kuh, D., Montasser, M.E., Kors, Jan A, Stewart C, Spector, T., Benaglio, Paola, Thompson, John R., Kerr, Kathleen F., Lundby A, Visscher PM, de Boer, R.A., P. Zitting, Erdmann, J., M. Nelis, Rioux, John D, P. I. de Bakker, Laiho P, A. A. Hicks, Bouchard, C., Paavo Zitting, Absher, Devin, Forouhi, Nita G, Dina C, van der Harst, Pim, S. M. Ring, Luigi Ferrucci, Leach, IM, Zitting P, de Boer, RA, Alicia Lundby, Olsen, J., Mika Kähönen, de Boer, R., Fuchsberger, Christian, Peal, D., Njajou, Omer T., Mihailov, E, Pim van der Harst, Heckbert SR, D. C. Rao, Beckmann, J.S., Bruce M Psaty, Olsen, JV, Lokki, Marja-Liisa L, Chambers, John C., Jula, A, Nita G Forouhi, Jamshidi, Y., Strachan, D., Ekelund, U, Polasek, O., A. Hofman, Ong, Ken K., Uitterlinden, A., Scott, R.A., Chanock, S., Kooner, Angrad S, Sinisalo, Juha, A. S. Kooner, Fischer, Krista, Harris, TB, Søren Brage, Jacqueline de Graaf, Lind, L, Harris, T., Wareham, Nicholas J., O'Connell, J.R., Chanock, SJ, Arking, Dan E., Lokki, Marja-Liisa L., J. Eriksson, Marcel den Hoed, Draisma, H.H., Draisma, Harmen H. M., Kemp, J., Go, Min Jin, Kääb, Stefan, Timpson, Nicholas J., Zhao, J.H., Singleton, A.B., Ekelund U, Yongmei Liu, S. Ketkar, K. Kristiansson, Maarten Leusink, Miller KA, Verschuren, W., Vitart, V, Bouatia-Naji, N, Rossin, E.J., N. Glorioso, Fuchsberger C, M. Lorentzon, Evans, David M., Hayward, C, Pramstaller PP, Kemp, JP, Assimes, Themistocles L, Jensen, M.K., van der Harst P, Strachan, DP, Whitfield, J.B., Luben, Robert N., Assimes, TL, Themistocles L Assimes, Assimes, T., Spector, TD, CHARGE-AF Consortium, Igor Rudan, J. C. Tardif, Kumari M, W. L. McArdle, Darbar D, Kronmal RA, Lunetta KL, Nieminen, M.S., Ferrucci, L., Glorioso, N., Hartikainen, A.L., Jouke-Jan Hottenga, Holewijn S, Kronmal, RA, Esko T, Leach, I.M., Müller Nurasyid M, Shin, J., Strachan, David P, R. A. de Boer, Kronmal, R., Lakatta EG, Stanton, Alice V., Samani, Nilesh J., Cisca Wijmenga, Bouatia-Naji, Nabila, Virtamo, J, Hofman, Bert, Hartikainen AL, Langenberg, Claudia, Markus, M.R.P., Hwang SJ, Olsen JV, Brundel, Bianca J. J. M., Marques-Vidal, Pedro, van Veldhuisen, Dirk J., Widen E, Ferrucci, Luigi, Sibon, O.C.M., W M Monique Verschuren, Jaban S Sehmi, Kirill V Tarasov, Feitosa, Mary F., Markus, M.R., Spector, Tim D., Jorma Viikari, Witteman JC, Snieder, H., Yengo L, Havulinna AS, Fuchsberger, C, S. A. McCarroll, Kay-Tee Khaw, S. E. Medland, Pouta, Anneli, Medland, Sarah E, Kraft, P, Rizzi, F., Lorentzon, Mattias, Pouta A, Sharp, Stephen, Khaw, K.-T., Sanna S, Stolk, Ronald P., Iribarren, C, Chambers, J., Almgren P, Marques Vidal P, Johansson, A, Chanock SJ, J. Yang, O'Donnell, Christopher J., Willemsen G, Mark Eijgelsheim, Havulinna, Aki S, K. K. Ong, Patricia B Munroe, Goyette, P, Chambers, JC, Peal, DS, Nona Sotoodehnia, R. A. Kronmal, Verschuren WM, de Geus, E.J.C.; id_orcid, B. Isomaa, Lokki, M.L., Albert, C., Hadley, D, Wild, S.H., Lunetta, K.L., Gonneke Willemsen, Isomaa B, Brundel, B.J.J.M., Stricker, B.H., Marques-Vidal, P., James F Wilson, Denis C Shields, Barlassina, Cristina, Stefansson, K., Forouhi, N.G., Albert, CM, Markku S Nieminen, Metspalu A, Cho, Yoon Shin, A. V. Segrè, Caroline Hayward, Willemsen, G, Harris, Tamara B., Hunter, David J., Boomsma, D.I.; id_orcid, Navarro, Pau; id_orcid, Stanton, Alice V, Gudbjartsson, D.F., Boomsma, D., Strachan, D.P., Luben, R., Peter Almgren, Uitterlinden, André; id_orcid, Ben A Oostra, Veronique Vitart, Rudolf A de Boer, Viikari, J, Rudan, Igor, Felix, Stephan B., Beckmann, Jacques S., Smith, George Davey, Luben, RN, Zitting, P., Nancy L Pedersen, Markus MR, Ingrid B Borecki, John B Whitfield, Wijmenga, Cisca, Weedon, Michael N, P. Almgren, Johnson, Toby, Salomaa V, O'Donnell, Christopher J, Rossin, E., Hsueh, WC, J. J. Hottenga, Xie, WJ, André G Uitterlinden, Wheeler W, Arnar, David O., T. Quertermous, Bouchard C, Thorsteinsdottir, U., den Heijer M, Cristina Barlassina, Wiek H van Gilst, Boomsma, DI, Waite, L, Xie, W., C. Dina, Daniele Cusi, Rossin, EJ, Sibon OC, Wong, Quenna, Spector, Tim D, Uitterlinden, A.G., Beckmann JS, K. T. Khaw, Sarah H Wild, Philippe Froguel, Ong, K., PR GWAS Consortium, M. Eijgelsheim, W. Zhang, Peters, A, Montgomery, Grant W., A. Hingorani, Kutalik, Z., Psaty, BM, Kaab, S, Spector TD, Ferrucci L, Feitosa, M.F., Walker, M., Oostra BA, Jaako Tuomilehto, Willemsen, G., Kahonen, M, Andrew B Singleton, Chung, M., Psaty, B.M., Boomsma, D.I., Quertermous, T, Westra, Harm-Jan, Nieminen, Markku S., Sinisalo, J, van der Klauw, Melanie M, Psaty, B., Dina, C, Hwang, S.-J., Kraft P, Grant W Montgomery, Pramstaller, Peter P, Hsueh, W., B. M. Psaty, Wijmenga, Cisca; id_orcid, Rudan, I, Shin, JT, Rudan, D, Vitart, V., Boucher, G., Felix, S.B., Milan DJ, Isaacs A, Junttila, Juhani, Juhani Junttila, Christian Fuchsberger, J. Luan, M. Kähönen, O'Connell, Jeffrey R., Hayward, Caroline; id_orcid, Bruno H Ch Stricker, Verschuren, W M Monique, Jian'an Luan, Heijer, Mariska, Song C, K. W. Knowles, Wendy L McArdle, Polasek, O, Boer, JMA, Wong, Andrew, Angrad S Kooner, Nilesh J Samani, D. Darbar, Ohlsson, Claes, Rizzi, Federica, J. Sinisalo, Milan, D., Stricker, Bruno H. Ch, Boehnke, M., N. G. Martin, Geus, E.J. de, Beckmann, J., U. Ekelund, Philippe Goyette, Jensen, Majken K., Kerr, K.F., Ellinor, P., Snieder, Harold; id_orcid, Shamika Ketkar, Bandinelli, S, Milani L, QRS GWAS Consortium, Sanna, S., J. Viikari, Junttila, J., Uitterlinden, Andre G., O. Polasek, Bianca J J M Brundel, Ketkar, Shamika, Rimm EB, Harm-Jan Westra, Lind, P.A., Song, C., Thorsteinsdottir U, Go, MJ, Sibon, OCM, Groop, L., Ellinor, PT, Sotoodehnia N, Walker, M, Loos, Ruth J F, Khaw KT, Munroe PB, T. Tanaka, Kutalik, Zoltan, Ellinor, P.T., Martin den Heijer, Johansson, Asa, Almgren, P., Timpson, Nicholas J, Hofman, A., Chung M, Lu Qi, Smith, Albert V, Milan, DJ, Kanon, Bart, Kanon, B., Lunetta, KL, Johansson A, Onland-Moret, N. Charlotte, S. R. Heckbert, Perola M, J. S. Kooner, den Hoed, Marcel +999 morecore +2 more sources
