Results 161 to 170 of about 518,643 (317)

A Human Immuno‐Lung Organoid Model to Study Macrophage‐Mediated Lung Cell Senescence Upon SARS‐CoV‐2 Infection

open access: yesAdvanced Science, EarlyView.
Immuno‐lung organoids are developed and used spatial transcriptomics to uncover how proinflammatory macrophages drive lung cell senescence via the THBS1–(ITGA3+ITGB1) axis in COVID‐19. To ensure broad accessibility, LungSpatialDB is created, an AI‐powered data portal, enabling intuitive exploration of spatial data and biological insights through ...
Yuling Han   +24 more
wiley   +1 more source

Cardiovascular Magnetic Resonance 3D LGE Imaging for Atrial Fibrillation Ablation understanding Left Atrial Structural Changes

open access: yesJournal of Cardiovascular Magnetic Resonance
Evangelia Nyktari, MD   +9 more
doaj   +1 more source

Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery. [PDF]

open access: yesCureus
Katerini M   +6 more
europepmc   +1 more source

Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction

open access: yesAdvanced Science, EarlyView.
Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu   +14 more
wiley   +1 more source

Pancreatic Cancer‐Derived Extracellular Vesicles Enriched with miR‐223‐5p Promote Skeletal Muscle Wasting Associated with Cachexia

open access: yesAdvanced Science, EarlyView.
EVs and EV‐microRNAs (miRNAs) mediate PDAC‐skeletal muscle communication. miR‐223‐5p reduces METTL14 transcription by targeting MAFA, which subsequently decreases m6A methylation in skeletal muscles, ultimately leading to muscle wasting. This study highlights the absorption of miRNA in PDAC‐derived EVs by skeletal muscles and reveals a previously ...
Kangjing Xu   +7 more
wiley   +1 more source

Cardiac Magnetic Resonance-aided Ventricular Tachycardia Substrate Ablation Using a Novel Research Image-navigated Late-gadolinium Enhancement Sequence

open access: yesJournal of Cardiovascular Magnetic Resonance
Evangelia Nyktari, MD   +9 more
doaj   +1 more source

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