Results 31 to 40 of about 4,065,133 (366)

The Establishment of Hypertrophic Cardiomyopathy Diagnosis Model via Artificial Neural Network and Random Decision Forest Method

Mediators of Inflammation, 2022
Hypertrophic cardiomyopathy is a hereditary disease characterized by asymmetric ventricular hypertrophy as the key anatomical feature. Currently, there exists no effective method for the early diagnosis of hypertrophic cardiomyopathy.
Shuanglei Li, Zekun Feng, Cangsong Xiao, Yang Wu, Weihua Ye   +4 more
doaj   +1 more source

Ascending Aorta Diameter Changes after Aortic Valve Replacement in Elderly Patients with Aortic Valve Stenosis

Cardiology Research and Practice, 2022
Objective. To describe the natural history of the ascending aorta in elderly patients after aortic valve replacement (AVR) for aortic valve stenosis and to clarify the risk factors associated with the progression of the ascending aorta. Methods.
Jiamiao Gong, Kang An, Hongyuan Lin, Jianfeng Hou   +3 more
doaj   +1 more source

Alterations in Portal Vein Flow and Intrarenal Venous Flow Are Associated With Acute Kidney Injury After Cardiac Surgery: A Prospective Observational Cohort Study

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018
Background Acute kidney injury (AKI) after cardiac surgery is associated with adverse outcomes. Venous congestion can impair kidney function, but few tools are available to assess its impact at the bedside.
W. Beaubien-Souligny, Aymen Benkreira, P. Robillard, N. Bouabdallaoui, M. Chassé, G. Desjardins, Y. Lamarche, Michel White, J. Bouchard, A. Denault   +9 more
semanticscholar   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Aortic root replacement and valvuloplasty in a woman with severe pectus excavatum [PDF]

Journal of Cardiovascular and Thoracic Research, 2018
We describe a case of a 43-year old woman with Marfan’s syndrome, tricuspid valve regurgitation and severe pectus excavatum who required an aortic root replacement and valvuloplasty for an ascending aortic aneurism with aortic valve regurgitation and ...
Panagiotis Kalogris, Kosmas Iliadis, Gregory Amanatidis, Alexandros Demis, Anna Smyrli, Konstantinos Petsios   +5 more
doaj   +1 more source

Six‐Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery

New England Journal of Medicine, 2018
Background We reported previously that, in patients undergoing cardiac surgery who were at moderate‐to‐high risk for death, a restrictive transfusion strategy was noninferior to a liberal strategy with respect to the composite outcome of death from any ...
David Mazer, R. Whitlock, D. Fergusson, E. Belley‐Cote, K. Connolly, Boris Khanykin, A. Gregory, É. de Médicis, F. Carrier, S. McGuinness, Paul J Young, K. Byrne, J. Villar, A. Royse, H. Grocott, M. Seeberger, C. Mehta, F. Lellouche, G. Hare, T. Painter, S. Fremes, S. Syed, S. Bagshaw, N. Hwang, C. Royse, Judith Hall, David Dai, Nikhil Mistry, K. Thorpe, S. Verma, P. Jüni, N. Shehata   +31 more
semanticscholar   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Repair of aortic arch aneurysm under cardiopulmonary bypass and deep hypothermia with low flow: A case report

Bangabandhu Sheikh Mujib Medical University Journal, 2016
Aortic arch surgery is the challenging and most difficult surgery among the cardiovascular operations. Cerebral and spinal complications are the most feared and common complications of aortic arch surgery.
Md. Rezwanul Hoque, Dinesh Gurung, Md. Alauddin, Shanker Bhandari, Rajat Pradhan, Mostafa Nuruzzaman   +5 more
doaj   +1 more source

Applying machine learning methods to predict operative mortality after tricuspid valve surgery

The Cardiothoracic Surgeon, 2023
Background EuroSCORE stratifies surgical risk in cardiac surgery; however, it is not explicitly for tricuspid valve surgery. Therefore, we aimed to apply machine learning (ML) methods to predict operative mortality after tricuspid valve surgery and ...
Amr A. Arafat, Sultan Alamro, Maha M. AlRasheed, Adam I. Adam, Huda Ismail, Claudio Pragliola, Monirah A. Albabtain   +6 more
doaj   +1 more source

Early delirium after cardiac surgery: an analysis of incidence and risk factors in elderly (≥65 years) and very elderly (≥80 years) patients

Clinical Interventions in Aging, 2018
Introduction Postoperative delirium is a common complication of cardiac surgery associated with increased mortality, morbidity, and long-term cognitive dysfunction. The aim of this study was to identify incidence and risk factors of delirium in elderly (≥
K. Kotfis, Aleksandra Szylińska, M. Listewnik, Marta Strzelbicka, M. Brykczyński, I. Rotter, M. Żukowski   +6 more
semanticscholar   +1 more source