Results 41 to 50 of about 899,396 (308)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Cardiac magnetic resonance findings predict increased resource utilization in elective coronary artery bypass grafting [PDF]

, 2008
Morbidity following CABG (coronary artery bypass grafting) is difficult to predict and leads to increased healthcare costs. We hypothesized that pre-operative CMR (cardiac magnetic resonance) findings would predict resource utilization in elective CABG ...
Alfakih, American Heart Association, Anna F. Dominiczak, Baks, Bellenger, Berry, Berry, British Heart Foundation Heart Statistics, Christian Delles, Colin Berry, Eisenberg, Ferguson, Fieno, Geissler, Geoffrey A. Berg, Gibbons, Hein, Henry J. Dargie, Higgins, Higgins, Hombach, John E. Foster, Lassnigg, Lorenz, Lukas U. Zimmerli, Lund, Mark, Michalopoulos, Mosteller, Mounsey, Nathanson, Pell, Pennell, Roques, Rosamond, Schvartzman, Selvanayagam, Sievers, Simonetti, Tracey Steedman, Tu, Tu, Zimmerli   +42 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The Establishment of Hypertrophic Cardiomyopathy Diagnosis Model via Artificial Neural Network and Random Decision Forest Method

Mediators of Inflammation, 2022
Hypertrophic cardiomyopathy is a hereditary disease characterized by asymmetric ventricular hypertrophy as the key anatomical feature. Currently, there exists no effective method for the early diagnosis of hypertrophic cardiomyopathy.
Shuanglei Li, Zekun Feng, Cangsong Xiao, Yang Wu, Weihua Ye   +4 more
doaj   +1 more source

Robert Edward Gross (1905-1988): ligation of a patent ductus arteriosus and the birth of a specialty. [PDF]

, 2014
The early 20th century saw an explosion in surgical expertise. Specialties dedicated to delicate organs such as the heart and vulnerable populations, like children, were in their infancy. Dr. William E.
Chalphin, BS, Alexander V., Cowan, MD, Scott W., Milan, MD, Stacey, Yeo, MD, Charles J.   +3 more
core   +1 more source

Modified Glucose-Insulin-Potassium Regimen Provides Cardioprotection With Improved Tissue Perfusion in Patients Undergoing Cardiopulmonary Bypass Surgery [PDF]

, 2020
Background Laboratory studies demonstrate glucose-insulin-potassium (GIK) as a potent cardioprotective intervention, but clinical trials have yielded mixed results, likely because of varying formulas and timing of GIK treatment and different clinical ...
Chen, Wensheng, Cui, Qin, Gao, Feng, Li, Jia, Liu, Jincheng, Ma, Xin-Liang, Wan, Yi, Yi, Dinghua, Yu, Shiqiang, Zhang, Yue, Zhao, Bijun, Zhao, Kun, Zhao, Rong   +12 more
core   +1 more source

Effect of socioeconomic deprivation on waiting time for cardiac surgery: retrospective cohort study [PDF]

, 2000
OBJECTIVE: To determine whether the priority given to patients referred for cardiac surgery is associated with socioeconomic status. DESIGN: Retrospective study with multivariate logistic regression analysis of the association between deprivation and ...
Cobb, S.M., Ford, I., Norrie, J., Pell, A.C.H., Pell, J.   +4 more
core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Ascending Aorta Diameter Changes after Aortic Valve Replacement in Elderly Patients with Aortic Valve Stenosis

Cardiology Research and Practice, 2022
Objective. To describe the natural history of the ascending aorta in elderly patients after aortic valve replacement (AVR) for aortic valve stenosis and to clarify the risk factors associated with the progression of the ascending aorta. Methods.
Jiamiao Gong, Kang An, Hongyuan Lin, Jianfeng Hou   +3 more
doaj   +1 more source

Robot-Assisted Cardiac Surgery

Annals of Thoracic and Cardiovascular Surgery, 2015
Recognition of the significant advantages of minimizing surgical trauma has resulted in the development of minimally invasive surgical procedures. Endoscopic surgery offers patients the benefits of minimally invasive surgery, and surgical robots have enhanced the ability and precision of surgeons.
Norihiko, Ishikawa, Go, Watanabe
openaire   +4 more sources