Results 271 to 280 of about 900,334 (369)
Artificial intelligence-based action recognition and skill assessment in robotic cardiac surgery simulation: a feasibility study. [PDF]
Atroshchenko GV+5 more
europepmc +1 more source
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu+17 more
wiley +1 more source
Preoperative Diagnostic Assessment of Patients with Cardiovascular Risk Factors Undergoing Noncardiac Surgery: A 2025 Update. [PDF]
Murthy NM+7 more
europepmc +1 more source
The authors have discovered that intracellular interleukin 1 receptor 2 (IL1R2) negatively regulates pyroptosis and inflammation by inhibiting glycolysis in sepsis. Soluble IL1R2 is released from macrophages undergoing pyroptosis. IL1R2 acts as a novel negative regulator of glycolysis by interacting with enolase 1 (ENO1), thereby inhibiting gasdermin D
Chuyi Tan+13 more
wiley +1 more source
Employing snRNA‐seq post‐MCAO‐induced retinal ischemia (RI), this study revealed a novel Hmga2‐high Müller cell subpopulation. Hmga2 knockout alleviated neuroinflammation and RI symptoms, potentially by binding PI3K and regulating Müller cell autophagy.
Weihao Lv+11 more
wiley +1 more source
Dual-Camera Port Setup Strategies for Totally Endoscopic Aortic and Mitral Valve Surgery. [PDF]
Goto Y+4 more
europepmc +1 more source
Wearable Bioelectronics for Home‐Based Monitoring and Treatment of Muscle Atrophy
As an inevitable disease, muscle atrophy has received more attention. Because the factors that induce this disease are diverse, achieving a complete cure is still impossible. Wearable bioelectronics provides a more comfortable, low‐cost, and efficient way of home care for the monitoring and treatment of muscle atrophy. Therefore, this review summarizes
Shuai Zhang+4 more
wiley +1 more source