Results 251 to 260 of about 1,084,670 (306)

Cardiomyopathy in a c.1528G>C Hadha mouse is associated with cardiac tissue lipotoxicity and altered cardiolipin species. [PDF]

J Lipid Res
Eke C, Babcock S, Gaston G, Elizondo G, Chung H, Asal A, Chatfield KC, Sparagna GC, DeBarber AE, Packwood W, Lindner JR, Gillingham MB.   +11 more
europepmc   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

NF-κB-Specific Suppression in Cardiomyocytes Unveils Aging-Associated Responses in Cardiac Tissue. [PDF]

Biomedicines
Morgado LAL, Rodrigues LMZ, Silva DCF, da Silva BD, Irigoyen MCC, Takano APC.   +5 more
europepmc   +1 more source

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

Advanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li, Yike Chen, Daniel Western, Muhammad Ali, Menghan Liu, Katherine Gong, Ying Xu, Joseph Lowery, David M. Holtzman, Chloe Robins, John D. Eicher, Yen‐Ning Huang, ShiWei Liu, Tamina Park, Andrew J. Saykin, Kwangsik Nho, Mahdi Moqri, Richard C. Mohs, Amelia Farinas, Patricia Moran‐Losada, Hamilton Se‐Hwee Oh, Tony Wyss‐Coray, Carlos Cruchaga   +22 more
wiley   +1 more source

Risk impact of SARS-CoV-2 coronavirus and spike protein on cardiac tissue: a comprehensive review. [PDF]

Physiol Res
Šerý O, Dziedzinska R.
europepmc   +1 more source

Thermosensitive Porcine Myocardial Extracellular Matrix Hydrogel Coupled with Proanthocyanidins for Cardiac Tissue Engineering. [PDF]

Gels
Hidalgo-Vicelis JL, Rivera-Contreras AR, Hernández-Téllez B, Piñón-Zárate G, Jarquín-Yáñez K, Fiordelisio-Coll T, Saniger-Blesa JM, González-Gómez GH, Falcón-Neri MA, Canales-Martínez MM, Castell-Rodríguez AE.   +10 more
europepmc   +1 more source

Pathophysiological insights into HFpEF from studies of human cardiac tissue. [PDF]

Nat Rev Cardiol
Fayyaz AU, Eltony M, Prokop LJ, Koepp KE, Borlaug BA, Dasari S, Bois MC, Margulies KB, Maleszewski JJ, Wang Y, Redfield MM.   +10 more
europepmc   +1 more source

Cardiac tissue engineering: an emerging approach to the treatment of heart failure. [PDF]

Front Bioeng Biotechnol
Rayat Pisheh H, Nojabaei FS, Darvishi A, Rayat Pisheh A, Sani M.   +4 more
europepmc   +1 more source

Cardiac fibroblast-mediated ECM remodeling regulates maturation in an in vitro 3D engineered cardiac tissue. [PDF]

J Tissue Eng
Jang Y, Kang M, Kang YG, Lee D, Jung HG, Yoon DS, Kim J, Park Y.   +7 more
europepmc   +1 more source