Results 101 to 110 of about 110,986 (307)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

The impact of night shift work on cortisol secretion

open access: yesQuality in Sport
Night-shift work poses significant challenges to human health, largely through disruption of circadian rhythms and dysregulation of cortisol secretion. Cortisol, a key glucocorticoid, regulates metabolism, immune function, and stress responses, following
Aleksandra Strawińska   +8 more
doaj   +1 more source

Cardinality Estimation in DBMS: A Comprehensive Benchmark Evaluation [PDF]

open access: green, 2021
Yuxing Han   +13 more
openalex   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Une gare de triage. Gestes, matériaux et figures dans Y Bush Corrida

open access: yesCaptures
Michel Neault, artiste du son, a passé des nuits dans une gare de triage enclavée dans un quartier résidentiel de Montréal. Il accompagne les répartiteurs, les wagonniers, les mécaniciens; il loge son silence dans leurs conversations, intercepte leurs ...
Serge Cardinal
doaj   +1 more source

Indoor Environmental Quality (IEQ) in Healthcare Settings and Cognitive Performance of Staff

open access: yesJournal of Education, Health and Sport
Introduction. Clinical work is performed under conditions of high cognitive load, time pressure and frequent interruptions. Research on patient safety has traditionally focused on sleep deprivation, fatigue and work organisation, whereas environmental ...
Michał Karol   +8 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Dietary Supplements and Popular Nutritional Strategies among Young Adults

open access: yesQuality in Sport
Dietary supplements and various nutritional strategies have become an integral part of young adults' lives in recent years, a trend observed in an increasing proportion of the population.
Michał Karol   +8 more
doaj   +1 more source

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