Results 161 to 170 of about 561,316 (319)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Complexity of parental number talk predicts preschoolers' gains in cardinal knowledge. [PDF]

Sci Rep
Geary DC, Simsek E, Gable S, Booker JA, Nugent L, Hoard MK.   +5 more
europepmc   +1 more source

Efficient binning for bitmap indices on high-cardinality attributes

, 2004
Doron Rotem, Kurt Stockinger, Kesheng Wu
openalex   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Evidence for chronological diversification of spinal neuron subtypes by a shared sequence of transcription factors. [PDF]

Sci Adv
Segarra LC, Sangster K, Sagner J, Kania A, Sagner A.   +4 more
europepmc   +1 more source

Refining Case Models Using Cardinality Constraints

, 2021
Stephan Haarmann, Marco Montali, Mathias Weske   +2 more
openalex   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Bistability and hysteresis in the proximity-based grouping of dot lattices. [PDF]

Sci Rep
Moazzen H, Gharibzadeh S, Bakouie F.
europepmc   +1 more source

Cardinal Code Theory: A Parameter-Free Unification from Cl(1,12)

Yuu Hatoma
openalex   +1 more source

Arrest and Conviction of Cardinal József Mindszenty 1948–1949. Part 1. “He wants to be a martyr, but I would not do him this favour”

, 2020
Margit Balogh
openalex   +2 more sources