Results 41 to 50 of about 2,380 (223)

Effective Correspondents to Cardinal Characteristics in Cichon's Diagram. [PDF]

In this thesis, we define and study Turing characteristics. These are sets of oracles of computation which compute members of Cantor space or Baire space which have certain combinatorial properties related to cardinal characteristics of the continuum ...
Rupprecht, Nicholas Andrew
core  

Set Theory (online meeting)

, 2020
Set theory continues to experience dramatic progress, both in pure set theory, with its fundamental techniques of forcing, large cardinals, and inner model theory, and in applied set theory, with its deep connections to other areas of mathematics ...

core   +1 more source

Tight Eventually Different Families

, 2022
Generalizing the notion of a tight almost disjoint family, we introduce the notions of a {\em tight eventually different} family of functions in Baire space and a {\em tight eventually different set of permutations} of $\omega$.
Switzer, Corey Bacal, Fischer, Vera
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Creatures und Kardinalzahlen [PDF]

, 2018
Diese Dissertation enthält mehrere verwandte Resultate über Kardinalzahlcharakteristiken des Kontinuums, welche unter Verwendung von Creature-Forcing bewiesen werden.
Klausner, Lukas Daniel
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Cichon's diagram, regularity properties and $/Delta^1_3$ sets of reals

, 2014
We study regularity properties related to Cohen, random, Laver, Miller and Sacks forcing, for sets of real numbers on the TeX level of the projective hieararchy.
Khomskii, Yurii, Fischer, Vera, Friedman, Sy David   +2 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source