Results 81 to 90 of about 1,869,033 (226)

Organoprotective effects of serelaxin in patients with severe decompensated heart failure

Рациональная фармакотерапия в кардиологии, 2016
Serelaxin (recombinant molecule of the human relaxin-2) is an innovative drug for the treatment of acute heart failure. Preclinical and clinical studies demonstrated the ability of serelaxin to relieve the symptoms of heart failure, provide a significant
Z. D. Kobalava, S. V. Villevalde, A. E. Solov'jova, I. A. Merai   +3 more
doaj   +1 more source

Spontaneous Chylothorax in a Case of Cardio-Facio-Cutaneous Syndrome

, 2009
A patient is reported who fulfills the diagnostic criteria for severe cardio-facio-cutaneous syndrome who developed a chylothorax.
CHAN, PEI-CHUN;CHIU, HSIEN-CHING;HWU, WUH-LIANG, 詹珮君;邱顯清;胡務亮   +1 more
core  

Cardio-renal interrelation: modern view

, 2020
The paper discusses the definition and classification of cardio-renal syndrome (CRS) - a pathological process in heart or kidneys, characterised by acute or chronic dysfunction of one organ which results in acute or chronic failure of the other organ ...
Villewalde S.V., Moiseev V.S., Efremovtseva M.A., Kobalava Z.D.   +3 more
core  

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

Experimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu, Xingyu Qiu, Nan Xu, Gensheng Zhang, Enyin Lai, Liang Zhao   +5 more
wiley   +1 more source

Menopause and vascular endothelial health: Is it all about the oestrogen?

Experimental Physiology, EarlyView.
Abstract Cardiovascular disease (CVD) is a leading cause of mortality in women, and CVD risk is accelerated during the menopause transition. This acceleration has traditionally been attributed to the hallmark decline in oestradiol with menopause. However, the menopause transition is also characterized by changes in other sex hormones that exert effects
Virginia R. Nuckols, Allyson I. Schwab, Lyndsey E. DuBose, Kerrie L. Moreau, Megan M. Wenner   +4 more
wiley   +1 more source

Cardio-renal-metabolic syndrome – an independent clinical picture?

Cardiologia Hungarica
Chronic kidney disease (CKD) and heart diseases (cardiovascular disease, atherosclerotic heart disease, heart failure) and metabolic diseases (metabolic syndrome [MetS], type 2 diabetes [T2DM], hyperuricemia) often occur together.
Ede Kékes
doaj   +1 more source

Role of hypoxia inducible factor pathway in cardiorenal syndrome and application prospect of HIF stabilizer

Linchuang shenzangbing zazhi, 2022
Cardiorenal syndrome （CRS） involves multiple organs. It refers to acute or chronic cardiac or renal dysfunction. Its pathophysiology involves immune inflammation，oxidative damage，anemia，iron metabolism disorders，dyslipidemia，hemodynamic disorders ...
A Rou-na, He Fang-fang, Sun Xin, Luo Chang-qing   +3 more
doaj  

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Cardio-renal anemia syndrome and Erythropoietin Stimulating Agents (ESA) [PDF]

, 2011
120004665359近年の様々な疫学調査や大規模臨床試験により，慢性腎臓病（CKD）が心血管疾患（CVD）の独立した危険因子であることが明らかになった．さらに，CKD のCVD へのリスクとなる間に介在する要因として，貧血が大きな役割を果たしていることが証明されてきた．このようにCKD,CVD，貧血がお互いに悪影響を及ぼし合い，悪循環を形成するという考えをcardio-renal-anemia syndromeと呼ぶようになった．保存期CKD やうっ血性心不全に対する介入は困難が予想される．一方で ...
出口, 雅子, 井上, 衛, 成宮, 博理, 山田, 博之, 原山, 拓也, 北川, 功幸, 熱田, 晴彦   +6 more
core  

Acute Kidney Injury in Heart Failure Revisited—The Ameliorating Impact of “Decongestive Diuresis” on Renal Dysfunction in Type 1 Acute Cardiorenal Syndrome: Accelerated Rising Pro B Naturetic Peptide Is a Predictor of Good Renal Prognosis

, 2017
There is mounting evidence that forward heart failure as manifested by low cardiac output alone does not define the degree of renal dysfunction in cardiorenal syndrome. As a result, the term “congestive renal failure” was coined in 2012 by Ross to depict
Nneoma Agbasi, Mohan Sengodan, Macaulay Onuigbo, Karen Rosario   +3 more
core   +1 more source