Results 81 to 90 of about 39,995 (259)
Correlation of serum cardiolipin levels with physical activity in type 2 diabetes mellitus patients
Italian Journal of MedicineCardiolipin, a critical phospholipid involved in mitochondrial function, has a potential role in the pathogenesis of type 2 diabetes mellitus.
Ayesha Aslam +7 more
doaj +1 more source
Diminished exercise capacity and mitochondrial bc1 complex deficiency in tafazzin-knockdown mice.
Frontiers in Physiology, 2013 The phospholipid, cardiolipin, is essential for maintaining mitochondrial structure and optimal function. Cardiolipin-deficiency in humans, Barth syndrome, is characterized by exercise intolerance, dilated cardiomyopathy, neutropenia and 3-methyl ...
Corey ePowers +3 more
doaj +1 more source
Cytoplasmic Lipid Membrane Biogenesis in Prokaryotes: From Soluble Lipid Building Blocks to a Dynamic and Functional Boundary Layer [PDF]
ChembiochemLipid membranes are fundamental to all prokaryotic life. Besides acting as barrier, by orienting as hydrophobic bilayer, lipids are involved in a wide variety of other cellular processes. As a consequence, prokaryotic membranes are dynamic entities that switch their lipid composition as required; a process that requires tight interplay with the lipid ...
Gan S, Exterkate M.
europepmc +2 more sources
A comprehensive review of cancer‐induced cardiac wasting
British Journal of Pharmacology, EarlyView.Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena +5 more
wiley +1 more source
Function of cardiolipin in mitochondria of Saccharomyces cerevisiae
, 2004 Cardiolipin and its precursor phosphatidylglycerol, phospholipids found uniquely in membranes engaged in oxidative phosphorylation, play important roles in multimeric complexes of the energy transducing system (ETS) associated with the inner ...
Zhang, Mei
core +1 more source
Isolation and purification of cardiolipin from beef heart.
Journal of Lipid Research, 1985 A simple and efficient procedure is described for the preparation of cardiolipin sodium salt from beef heart. A crude phospholipid fraction is isolated by chloroform-methanol extraction of the homogenized tissue, followed by acetone precipitation and ...
E B Smaal +4 more
doaj +1 more source
Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights
British Journal of Pharmacology, EarlyView.Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra +5 more
wiley +1 more source
TRIM59 Drives Bladder Cancer Progression Through E3 Ligase‐Dependent K48‐Linked Degradation of PTRF
Cancer Science, EarlyView.Schematic model of TRIM59‐driven BLCA progression through K48‐linked ubiquitination and proteasomal degradation of PTRF, leading to AKT activation and c‐Myc upregulation. ABSTRACT Tripartite motif‐containing 59 (TRIM59) is an E3 ubiquitin ligase implicated in multiple malignancies, but its role in bladder cancer (BLCA) remains incompletely understood ...
Junlin Gan +9 more
wiley +1 more source
Docosahexaenoic acid accumulates in cardiolipin and enhances HT-29 cell oxidant production
Journal of Lipid Research, 1998 The objective of this study was to investigate membrane fatty acids for their effects on mitochondrial function in live cells. Mitochondrial potential and oxidant production were measured in human colonic adenocarcinoma (HT-29) cells with membranes ...
Steven M. Watkins +2 more
doaj +1 more source
The FEBS Journal, EarlyView.DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam +4 more
wiley +1 more source