Results 111 to 120 of about 32,658 (216)
Alveolar macrophages: development, respiratory homeostasis, signal pathways, diseases, and therapeutic opportunities: During embryonic development, fetal progenitors migrate to the developing lungs via a CX3CR1‐dependent mechanism to establish the TrAM pool.
Sihan Yang +4 more
wiley +1 more source
Radiotherapy‐Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments
Radiotherapy for malignancies frequently injures the organs’ systems through oxidative stress, fibrosis, inflammation, and vascular damage. This review systematically maps the epidemiology, pathogenesis, and emerging therapies to propose a mechanism‑network‑targeted framework for integrated, personalized care in radiation oncology.
Xiaowen Ma +9 more
wiley +1 more source
Strategy for modular assembly of tetravalent, multispecific antibodies
Abstract Multispecific, multivalent antibodies (Abs) are a burgeoning class of drugs that dramatically expand the pharmacological repertoire beyond traditional therapeutic Abs. Here, we present a simple, modular approach to developing multispecific, multivalent Abs based on a Fab‐phage library with a single light chain.
Evan Mallette +12 more
wiley +1 more source
Elamipretide Rejuvenates Oocyte Quality and Restores Female Fertility During Reproductive Aging
We reported a novel peptide therapy showing that elamipretide restores the quality of aged oocytes for fertility by coordinately boosting oocyte nuclear and cytoplasmic maturation via activation of the VEGF signaling pathway. ABSTRACT Aging represents a major contributor to the deterioration of female fertility, with oocyte quality being the central ...
Hao‐Lin Zhang +12 more
wiley +1 more source
ABSTRACT Introduction Lupus anticoagulant (LA) testing is essential, albeit complex, in the laboratory diagnosis of antiphospholipid syndrome (APS). Given the multi‐step workflow and the variability introduced by anticoagulant therapy, reagent differences, and interpretive approaches, result interpretation requires expert evaluation.
Chiara Novelli +4 more
wiley +1 more source
Abstract This mini‐review examines odd‐carbon polyunsaturated fatty acids (odd‐PUFAs), a rare but biologically significant group of fatty acids in photosynthetic microorganisms. Odd‐PUFAs are straight‐chain fatty acids containing an odd number of carbon atoms and two or more methylene‐interrupted double bonds. They typically account for less than 1% of
Linda Nedbalová +2 more
wiley +1 more source
Making sense of cardiomyopathy caused by deletion of acetyl-CoA carboxylase 1 and 2. Reply. [PDF]
Kim CW, Mitsche MA, Horton JD.
europepmc +1 more source
Making sense of cardiomyopathy caused by deletion of acetyl-CoA carboxylase 1 and 2. [PDF]
Tian R, Lewandowski ED.
europepmc +1 more source

