Results 61 to 70 of about 39,995 (259)

Cardiolipin and mitochondrial carriers

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2009
Members of the mitochondrial carrier family interact with cardiolipin (CL) as evident from a variety of functional and structural effects. CL stabilises carrier proteins on isolation with detergents, with the P(i) carrier as the prime example. CL is required for transport in reconstituted vesicles, prime examples are the P(i)- and ADP/ATP carrier (AAC).
openaire   +2 more sources

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Nutrition and Metabolic Diseases: A Systematic Review of Functional Foods, Medicinal Plants, Phytochemicals, Bioactive Compounds and Nutrients Effective Against Metabolic Diseases

Food Chemistry International, EarlyView.
The study demonstrates how functional foods, medicinal plants, phytochemicals, bioactive compounds and essential nutrients combat metabolic diseases. It highlights their mechanisms, including antioxidant, anti‐inflammatory, insulin‐sensitising, lipid‐regulating, gut microbiota‐modulating and mitochondrial‐enhancing effects, leading to improved ...
Chinaza Godswill Awuchi, Sana Noreen, Sonia Morya   +2 more
wiley   +1 more source

Linoleic acid supplemention of Barth syndrome fibroblasts restores cardiolipin levels: implications for treatment

Journal of Lipid Research, 2003
The object of this study was to investigate whether the levels of cardiolipin in cultured skin fibroblasts of patients with Barth syndrome (BTHS) can be restored by addition of linoleic acid to growth media.
F. Valianpour, R.J.A. Wanders, H. Overmars, F.M. Vaz, P.G. Barth, A.H. van Gennip   +5 more
doaj   +1 more source

Shifting of Cardiolipin Species in Cell Cycle.

, 2014
HT1080 cells were arrested by serum starvation, and revived from 10% FBS. Cells were harvested at 22 hr for cardiolipin extraction in triplicates. Cardiolipin species were measured by mass spectrometry and normalized by total extracted ion counts among ...
Yuan-Hao Howard Hsu (665876), Wei-Ting Chao (665875), Wan-Hsin Chang (665873), Hsiu-Chi Ting (665874), Yu-Jen Chao (665872)   +4 more
core   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Loss of cardiac tetralinoleoyl cardiolipin in human and experimental heart failure

Journal of Lipid Research, 2007
The mitochondrial phospholipid cardiolipin is required for optimal mitochondrial respiration. In this study, cardiolipin molecular species and cytochrome oxidase (COx) activity were studied in interfibrillar (IF) and subsarcolemmal (SSL) cardiac ...
Genevieve C. Sparagna, Adam J. Chicco, Robert C. Murphy, Michael R. Bristow, Christopher A. Johnson, Meredith L. Rees, Melissa L. Maxey, Sylvia A. McCune, Russell L. Moore   +8 more
doaj   +1 more source

The physicochemical properties of cardiolipin bilayers and cardiolipin-containing lipid membranes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2009
In this review article, we summarize the current state of biophysical knowledge concerning the phase behavior and organization of cardiolipin (CL) and CL-containing phospholipid bilayer model membranes. We first briefly consider the occurrence and distribution of CL in biological membranes and its probable biological functions therein. We next consider
Lewis, Ruthven N.A.H., McElhaney, Ronald N.   +1 more
openaire   +2 more sources

Figure 5: Tetralinoleoyl Cardiolipin With Elamipretide Treatment

, 2019
(A) The effect of HF on tetralinoleoyl cardiolipin (mass-to-charge ratio, 1,448) in untreated samples is expressed as a percentage of total cardiolipin.
Genevieve C. Sparagna (299454), Brian L. Stauffer (6820697), Kathryn C. Chatfield (646110), Shelley D. Miyamoto (6820694), Max B. Mitchell (6820688), Carmen C. Sucharov (6820691), Elisabeth K. Phillips (6820685), Muhammad Aftab (4261855), Sarah Chau (6820682), Amrut V. Ambardekar (396783)   +9 more
core   +1 more source

Relationship between cardiolipin metabolism and oxygen availability in Bacillus subtilis [PDF]

, 2013
We report changes of the content of anionic phospholipids in Bacillus subtilis in response to hypoxic conditions and inhibition of terminal respiration.
Roberto Angelini, Simona Lobasso, Luigi L. Palese, PALESE, LUIGI LEONARDO, Angela Corcelli, CORCELLI, Angela, LOBASSO, SIMONA, ANGELINI, ROBERTO   +7 more
core   +1 more source