Results 91 to 100 of about 611,997 (371)

Chip-based frequency combs sources for optical coherence tomography [PDF]

open access: yes, 2019
The Optical coherence tomography (OCT) is a powerful interferometric imaging technique widely used in medical fields such as ophthalmology, cardiology and dermatology, for which footprint and cost are becoming increasingly important. Here we present a platform for miniaturized sources for OCT based on chip-scale lithographically-defined microresonators.
arxiv   +1 more source

A Compound Screen Based on Isogenic hESC‐Derived β Cell Reveals an Inhibitor Targeting ZnT8‐Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress‐Induced Cell Death

open access: yesAdvanced Science, EarlyView.
Pancreatic β cell loss by cellular stress contributes to diabetes pathogenesis. The study demonstrates that WFS1–ZnT8–zinc axis regulates vicious cycle of zinc transportation and cellular stress in pancreatic β cell. Based on that, the study applies a strategy for compound screening targeting ZnT8 based on human models, and identifies anisomycin, as a ...
Rui Hu   +19 more
wiley   +1 more source

The Synchrosqueezing transform for instantaneous spectral analysis [PDF]

open access: yesarXiv, 2014
The Synchrosqueezing transform is a time-frequency analysis method that can decompose complex signals into time-varying oscillatory components. It is a form of time-frequency reassignment that is both sparse and invertible, allowing for the recovery of the signal.
arxiv  

GLS1‐Mediated Redundancy in Glutamate Accelerates Arterial Calcification via Activating NMDAR/Ca2+/β‐Catenin Pathway

open access: yesAdvanced Science, EarlyView.
GLS1 is a novel contributor to arterial calcification. GLS1‐catalyzed glutamate exerts the promoting effects on osteogenic reprogramming in arteries. NMDAR, a glutamate receptor, is also activated and overexpressed during arterial calcification.
Ziting Zhou   +18 more
wiley   +1 more source

HISTORY OF CARDIOLOGY

open access: yesThe American Journal of the Medical Sciences, 1927
Mode of access: Internet. ; Presentation copy with autographs of both authors and manuscript note: no. 20.
Bishop, Louis Faugères, 1864-1941.   +1 more
openaire   +1 more source

3D‐Printed Biomimetic Vascular Scaffold Crosslinked with Heparan Sulfate for Sustained Release of PDGFB‐LG4 Fusion Protein Promotes Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Fusion protein PDGFB‐LG4 exhibits superior osteoinductive and angiogenic activity compared to PDGFB. The PCLHS‐PDGFB‐LG4 scaffold, featuring perfusable and permeable vascular‐like networks, promotes angiogenesis and osteogenesis through the sustained release of PDGFB‐LG4, thereby accelerating the bone defect repair process.
Jiahua Duan   +6 more
wiley   +1 more source

Experience of Teaching Pediatric Cardiology to the Students of IV and VI Courses of Medical Faculty at the Department of Intermediate Level Pediatrics

open access: yesZdorovʹe Rebenka, 2014
While teaching pediatric cardiology to the students of IV and VI courses of medical faculty at the department of intermediate level pediatrics, there is being used the combination of modern innovative technologies and traditional practice-oriented ...
T.Ye. Shumna
doaj   +1 more source

Supervised Laplacian Eigenmaps with Applications in Clinical Diagnostics for Pediatric Cardiology [PDF]

open access: yesarXiv, 2012
Electronic health records contain rich textual data which possess critical predictive information for machine-learning based diagnostic aids. However many traditional machine learning methods fail to simultaneously integrate both vector space data and text.
arxiv  

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