Results 91 to 100 of about 908,962 (359)

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

open access: yesAdvanced Science, EarlyView.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu   +10 more
wiley   +1 more source

Effects of Dexmedetomidine or Propofol on Postoperative Oxygenation Index During Invasive Ventilation in Patients After off-Pump Coronary Artery Bypass Grafting: a Single-Center Retrospective Study

open access: yesInternational Journal of General Medicine
Fang Li,1 Luwei Ma,1 Suhua Yan,2 Dongyi Liu3 1Department of Cardiac Surgery, Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, People’s Republic of China; 2Department of Cardiovascular Medicine, Provincial Hospital ...
Li F, Ma L, Yan S, Liu D
doaj  

World wide web and scientific publishing [PDF]

open access: yes, 1999
The relationship of scientific publishing and the world wide web steadily evolves as the internet technology advances in its sophistication and ability to reach an increasing number of people.
Abdulla, Ra-id
core   +1 more source

Genetically Engineered Light‐Responsive In Situ Hydrogels for Immunomodulation and Multimodal Therapy in Metastatic Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Cysteine‐tagged silk‐elastin‐like proteins, a family of tri‐block chimeric proteins that consist of a photothermal agent binding motif, silk motif, and elastin motif is developed to form a responsive in situ hydrogel for late‐stage and metastatic triple‐negative breast cancer.
Xinchen Shen   +11 more
wiley   +1 more source

Characteristics and Efficacy of Warfarin Sodium Tablet Subdivided by 3D Printing Technology: A Retrospective Cohort Study of Patients After Prosthetic Valve Replacement

open access: yesDrug Design, Development and Therapy
Jieqiong Lv,1 Kaixia Fu,2 Lingjuan Xiong,3 Bishan Chen,4 Luchuan Zhan,3 Jiang Liu,3 Zhanyi Lin,5 Fan Yang,2,4 Jisheng Chen4 1Department of Pharmacy, The Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, People’s ...
Lv J   +8 more
doaj  

Telemedicine and cardiology

open access: yesMedicinski pregled, 2003
Introduction Telecommunications and information technology provide clinical care at distance by means of telemedicine. Hospitals and other health care facilities use medical telemetry devices for monitoring patients' vital signs. These portable devices are used for measuring patient vital signs such as ECG, blood pressure, heart rate, respiration ...
Nikola, Jelkić   +5 more
openaire   +3 more sources

Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities

open access: yesAdvanced Science, EarlyView.
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao   +21 more
wiley   +1 more source

Regulatory Effects of Zhenxin Formula in Treating Doxorubicin-Induced Heart Failure: Network Pharmacology and Animal Experimental Verification

open access: yesDrug Design, Development and Therapy
Qiong Wu,1,* Hao Wang,2,* You Hua Wang,1 Jun Du,3 Bo Li,3 Xiao-Na Gan,3 Chen-Yang Liu,2 Jing Liang,2 Chang Liu,2 Min Cao2 1Department of Cardiology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine ...
Wu Q   +9 more
doaj  

The continual innovation of commercial PET/CT solutions in nuclear cardiology: Siemens Healthineers [PDF]

open access: hybrid, 2018
B. Bendriem   +6 more
openalex   +1 more source

Home - About - Disclaimer - Privacy