Results 71 to 80 of about 721,847 (303)

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Major achievements in cardiology in the past century: influence on Dutch cardiovascular medicine

, 2009
At the occasion of the 75th anniversary of the Netherlands Society of Cardiology, it is interesting to look back on the major scientific achievements in cardiovascular medicine of the last century, and to pail attention to the impact of these ...
de Boer, M-J, Wilde, A. A., van der Wall, E. E., F. Zijlstra, P. A. Doevendans, Doevendans, P. A., M-J de Boer, A. A. Wilde, Zijlstra, F., E. E. van der Wall, de Boer, M.-J.   +10 more
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Non-cardiology vs. cardiology care of patients with heart failure and reduced ejection fraction is associated with lower use of guideline-based care and higher mortality : Observations from The Swedish Heart Failure Registry

, 2021
Background: Patients with heart failure (HF) are often cared for by non-cardiologists. The implications are unknown. Methods: In a nationwide HF cohort with reduced ejection fraction (HFrEF), we compared demographics, clinical characteristics, guideline ...
Thorvaldsen, Tonje, Benson, L, Lund L. H., Kapelios C. J., Hage, C,, Dahlstrom, U, Lund, LH, Savarese, G,, Benson, Lina, Dahlstrom U., Kapelios, Chris J., Benson, Lina,, Lund, Lars H.,, Dahlström, Ulf, Canepa, Marco,, Canepa, Marco, Canepa M., Savarese, Gianluigi, Canepa, M, Thorvaldsen, Tonje,, Thorvaldsen T., Benson L., Savarese G., Thorvaldsen, T,, Lund, Lars H., Kapelios, Chris J.,, Kapelios, CJ, Hage, Camilla, Hage C., Dahlström, Ulf,, Savarese, Gianluigi,, Hage, Camilla,   +31 more
core   +1 more source

Asymmetrically Coordinated Dual‐Atom Manganese Contrast Agents Enabling High‐Efficiency T1 Enhanced MRI for Precise Tumor Visualization

Advanced Science, EarlyView.
A novel dual‐atom manganese MRI contrast agent (Mn‐BN) with a unique asymmetric coordination geometry provided a promising platform for sensitive and specific tumor imaging. In mice model, Mn‐BN nanoparticles precisely functioned as both a primary tumor‐specific enhancer in subcutaneous models and a hepatocyte‐specific agent in liver metastases models ...
Ding Yang, Qing‐Yang Li, Jianli Liang, Gengyou Li, Nan Sun, Qianqian Song, Haitao Zhu, Xiaoting Li, Zechuan Li, Jiankai Dong, Weisheng Guo, Yafang Xiao, Chun‐Sing Lee, Ying‐Shi Sun   +13 more
wiley   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source

Clinical Considerations for Competitive Sports Participation for Athletes With Cardiovascular Abnormalities: A Scientific Statement From the American Heart Association and American College of Cardiology.

This American Heart Association/American College of Cardiology scientific statement on clinical considerations for competitive sports participation for athletes with cardiovascular abnormalities or diseases is organized into 11 distinct sections focused ...
Halle, M., Krishnan, S., Kim, J.H., Thompson, P.D., Salerno, J.C., Brothers, J.A., Economy, K.E., Wilhelm, M., Ackerman, M.J., Drezner, J.A., Gray, B., Castelletti, S., Shah, A.B., Dickert, N.W., Singh, T.K., Papadakis, M., Kovacs, R.J., Börjesson, M., Braverman, A.C., Day, S.M., Dean, P.N., Etheridge, S.P., Wasfy, M.M., Guseh Ii, J.S., Sharma, S., Lampert, R., La Gerche, A., Shafer, K.M., Stewart, K.M., Martinez, M.W., Eijsvogels, TMH, Baggish, A.L., Link, M.S., Dineen, E.H., Gati, S., Allen, L.A., Maron, M., Emery, M.S., Pelliccia, A., Claessen, G., D'Ascenzi, F., Harmon, K.G., Phelan, D.M., Darden, D., Molossi, S., Churchill, T.W., Levine, B.D., Chung, E.H., Hsu, J.J.   +48 more
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Mentors in Cardiology

JACC: Cardiovascular Interventions, 2009
![Figure][1] We have recently lost some important friends in the Atlanta cardiology community, and this has caused me to reflect on their collective legacies. I am compelled to share some general thoughts about the importance of the mentor in cardiology.
openaire   +2 more sources

A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

Advanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng, Shiteng Cai, Jinfeng Gao, Sheng Zhao, Bohan Wei, Xueyi Weng, Zhengmin Wang, Qiaozi Wang, Qiyu Li, Chengzhi Han, Weiyan Li, Yiwen Tan, Yuyuan Fu, Meng Ji, Zheyong Huang, Yanan Song, Juying Qian, Junbo Ge   +17 more
wiley   +1 more source

Role of Rotablation in interventional cardiology

, 2018
With the increasing calcification of plaques, especially in the older population and those with multiple comorbidities, interventional cardiology has faced a lot of challenges. Rotational Atherectomy is type of percutaneous coronary intervention used in
Issack, Barke Mohamed
core  

A paediatric telecardiology service for district hospitals in south-east England: an observational study.

, 2008
The attached article is a Publisher version of the final published version which may be accessed at the link below. Copyright © 2010 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Young, TC, Young, TA, Rowlinson, G., Mistry, Hema, Dowie, Robin, Young, Tara, Weatherburn, G, Franklin, RC, Mistry, M., Franklin, R.C.G.G., Franklin, R. C. G., Weatherburn, G., Young, T. A., Dowie, R, Rigby, M, Mistry, H, Rigby, M., Young, T., Franklin, RCG, Dowie, R., Rowlinson, G, Weatherburn, Gwyn   +21 more
core   +1 more source