Results 71 to 80 of about 734,643 (308)

How Did the Updated 2019 European Society of Cardiology/European Atherosclerosis Society Risk Categorization for Patients with Diabetes Affect the Risk Perception and Lipid Goals? A Simulated Analysis of Real-life Data from EPHESUS Study [PDF]

, 1989
Background: The recent 2019 European Society of Cardiology/European Atherosclerosis Society practice guidelines introduced a new risk categorization for patients with diabetes. We aimed to compare the implications of the 2016 and 2019 European Society of
Mert, Kadir Uğur, Çil, Cem, Demirhan, Funda, Başaran, Özcan, Çelik, Oğuzhan, Doğan, Volkan, Özlek, Bülent, Özlek, Eda, Biteker, Murat, İnci, Sinan, Mert, GURBET ÖZGE, Selami Demirelli, Uğur Mert, Kadir, Aktaş, Müjdat, Akay, Kadriye Halli, Halil Özdemir, İbrahim, Derviş, Emir, Kalçık, Macit, Murat Resulzade, Mübariz, Mübariz Murat Resulzade, Halli Akay, Kadriye, Cem Çil, Göksel Çinier, Meral Kayıkçıoğlu, Kayikcioglu, Meral, Sinan İnci, Özpamuk Karadeniz, Fatma, Demir, Vahit, Aşkın, Lütfü, İbrahim Rencüzoğulları, Çinier, Göksel, Özcan Başaran, Bülent Özlek, Özdemir, Cem Çil İbrahim Halil, Lütfü Bekar, Özge Mert, Gurbet, Mehmet Tekinalp, Nihat Pekel, Tekinalp, Mehmet, Eda Özlek, Rencüzoğulları, İbrahim, Fatma Özpamuk Karadeniz, Macit Kalçık, Pekel, Nihat, Oğuzhan Çelik, Erkan Gencer, Resulzade, Müjdat Aktaş Mübariz Murat, Şenol, Utku, Gurbet Özge Mert, Bekar, Lütfü, Demirelli, Selami, Kadriye Halil Akay, Lütfü Aşkın, Gencer, Erkan, Volkan Doğan, Emir Derviş, Kadir Uğur Mert, İbrahim Halil Özdemir, Gökhan Aksan, Utku Şenol, ..., Müjdat Aktaş, Vahit Demir, Karadeniz, Fatma Özpamuk, Kayıkçıoğlu, Meral, Murat Biteker, Aksan, Gökhan   +66 more
core   +2 more sources

A Hepatocyte‐to‐Stellate Cell Axis Couples Alternate‐Day Fasting to Liver Fibrosis Resolution via ATG7 S‐Nitrosylation

Advanced Science, EarlyView.
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang, Mengqi Zeng, Cunxiao Sun, Yuhan Gou, Zhaode Feng, Weiqiang Lv, Chaoying Yan, Hansen Wu, Pengfei Zhang, Jie Xu, Ke Cao, Hao Li, Mingge Ding, Zhongbo Liu, Xing Zhang, Jiankang Liu, Xuan Zou, Zhihui Feng   +17 more
wiley   +1 more source

Relationship Between Hyperinsulinemia and Coronary Microvascular Disease

Diabetes, Metabolic Syndrome and Obesity
Qiang Tan,1 Chenhong Zu,2 Wenli Zhang,1 Jia Hao,2 Yang Li,2 Qiang Lu,3 Zhimeng Li,2 Yao Guo2 1Department of Cardiology, Peking University Third Hospital Qinhuangdao Hospital, Qinhuangdao, Hebei, People’s Republic of China; 2Department of Cardiology, the ...
Tan Q, Zu C, Zhang W, Hao J, Li Y, Lu Q, Li Z, Guo Y   +7 more
doaj  

The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ

Advanced Science, EarlyView.
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi, Yu‐Hui Gu, Kai‐Wen Ren, Xiao‐Hong Yu, Yun‐Long Xia, Xiao‐Lei Yang, Hui‐Hua Li   +6 more
wiley   +1 more source

Real-World Assessment of the Association Between PCSK9i Adherence and LDL Reduction and Variability in a Chinese Clinical Practice

Clinical Epidemiology
Xiaomin Ye,1,2,* Shaozhao Zhang,1,2,* Xiangbin Zhong,1,2 Miaohong Li,1,2 Menghui Liu,1,2 Xiaodong Zhuang,1,2 Xinxue Liao1,2 1Cardiology Department, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, People’s Republic of China ...
Ye X, Zhang S, Zhong X, Li M, Liu M, Zhuang X, Liao X   +6 more
doaj  

A Facial Foundation Model for Clinical Biomarker Prediction and Real‐World Mobile Deployment

Advanced Science, EarlyView.
MedicalFaceFound is a facial foundation model developed through three‐stage progressive pre‐training, adapting representations from general vision to facial structure and clinical phenotypes. Using a single facial image, it estimates 62 biomarkers across multiple physiological systems and supports downstream risk prediction for cardiovascular ...
Tingfeng Xu, Huixuan Xu, Li Lin, Fei Wang, Yaodong Ding, Shuangqiao Liao, Xingyu Chen, Jichen Wen, Hongqiang Zhao, Jing Hao, Weixiang Zhao, Gong Zhang, Shiguang Shan, Yong Zeng, Hu Han, Minxian Wang   +15 more
wiley   +1 more source

Application of Mixed/Augmented Reality in Interventional Cardiology

This review explores the transformative applications of augmented reality (AR) and mixed reality (MR) technologies in interventional cardiology. The integration of these cutting-edge systems offers unprecedented potential to enhance visualization ...
Mohsen Annabestani, Ali Olyanasab, Bobak Mosadegh   +2 more
core   +1 more source

A Hybrid Hierarchical Framework for Quantifying Mechanical Markers in Atherosclerotic Disease Progression: A New Approach for Diagnosis and Risk Assessment

Advanced Science, EarlyView.
The mechanobiological basis of atherosclerotic progression and its contribution to spatial and temporal heterogeneity remain incompletely understood. Spatially resolved AFM measurements revealed that plaque formation and distinct regions (cap fibrosis, intimal fibrosis, and lipid‐rich core) exhibit heterogeneous elastic modulus and viscoelastic ...
Yidan Zhou, Zhuo Chang, Xianjun Wu, Sijie Wang, Yuzhi Zhang, Hao Zhang, Haoyu Xu, Ruining Peng, Zhe Wang, Huiyun Xu, Yu Liu, Guangkui Xu, Nu Zhang, Hui Yang   +13 more
wiley   +1 more source

Linking Metabolic and Mitochondrial Stress to Regulated Cell Death and Inflammatory Organ Injury in Sepsis

Journal of Inflammation Research
Guohairong Pan,1,* Lulu Zhou,2,* Ruochong Wang,1,* Fei Gao,3 Shuai Li,4 Jingwei Kong,1 Chen Xin,1 Liangyu Cui,1 Xingyu Zhao,1 Liying Wang11Research Center for Standards of Traditional Chinese Medicine, Institute of Basic Research ...
Pan G, Zhou L, Wang R, Gao F, Li S, Kong J, Xin C, Cui L, Zhao X, Wang L   +9 more
doaj  

Extracellular Vesicle Packaged TDP43 Derived From ECs Exacerbates Cigarette Tar‐Related Atherosclerosis Progression via Enhancing Macrophage Extracellular Traps

Advanced Science, EarlyView.
Cigarette tar triggers EC‐derived EVs carrying TDP43, which binds VDAC1 to boost MAMs, mitochondrial Ca2+ overload, and METs formation in macrophages, accelerating smoking‐related AS progression, while retinoic acid binds TDP43 to block this pathogenic cascade.
Xinxin Zhu, Yuwu Chen, Wei Meng, Biyi Xu, Junke Mou, Xiaolin Liu, Mengyang Wang, Qishuo Gu, Qianhui Sun, Man Li, Chen Zhao, Ming Zeng, Ying Lv, Boling Yi, Sheng Qu, Xiaoxuan Bai, Ji Li, Xing Luo, Sining Hu, Bo Yu, Haibo Jia   +20 more
wiley   +1 more source