Results 141 to 150 of about 908,962 (359)

BHLHE40 Orchestrates Effector Tissue‐Resident Memory CD8+ T Cells and Limits Long‐Term Survival of Kidney Graft

open access: yesAdvanced Science, EarlyView.
An effector subset of TRM, defined as CD49a+PD1hi CD8+ TRM, represents a BHLHE40‐orchestrated resident immune component that, rather than circulating cells, plays as a major contributor to allograft rejection. ABSTRACT Tissue‐resident memory T cells (TRM), which function against tumors, infections, and non‐self antigens in organ transplantation ...
Junbo Li   +9 more
wiley   +1 more source

Current approach to the diagnosis of sarcopenia in cardiovascular diseases

open access: yesFrontiers in Nutrition
Muscle wasting syndrome, also known as sarcopenia, is an age-related geriatric condition characterized by a gradual loss of muscle mass, strength, and function. Sarcopenia can be classified into primary and secondary types.
Xu Han   +3 more
doaj   +1 more source

Promoting Medication Adherence in the Elderly: Factors and Insights From a Cross‐Sectional Study

open access: yesAGING MEDICINE, EarlyView.
The present study reviewed the factors of medication adherence in the elderly. By understanding these factors, we can develop targeted strategies to promote better medication adherence, ultimately improving health outcomes for this population. ABSTRACT Objectives This study reviewed the factors involved in medication adherence among the elderly.
Shokofeh Afkhami   +3 more
wiley   +1 more source

The Clinical Utility of a Precision Medicine Blood Test Incorporating Age, Sex, and Gene Expression for Evaluating Women with Stable Symptoms Suggestive of Obstructive Coronary Artery Disease: Analysis from the PRESET Registry. [PDF]

open access: yes, 2019
Background: Evaluating women with symptoms suggestive of coronary artery disease (CAD) remains challenging. A blood-based precision medicine test yielding an age/sex/gene expression score (ASGES) has shown clinical validity in the diagnosis of ...
Budoff, Matthew J   +9 more
core   +1 more source

Mechanism of RNA Oxidation and Its Inhibitor Involved in Ang II‐Induced Cardiomyocyte Hypertrophy

open access: yesAGING MEDICINE, EarlyView.
The oxidative damage of RNA is involved in the process of cardiomyocyte hypertrophy. The mechanism may be that 8‐oxoG, a product of RNA oxidation, activates the downstream ERK‐MAPK signaling pathway. ABSTRACT Objectives To explore the mechanism of RNA oxidation and its inhibitor MTHI involved in cardiomyocyte hypertrophy.
Tong Liu, Jin Bian
wiley   +1 more source

Inherited Hypertrabeculation? Genetic and Clinical Insights in Blood Relatives of Genetically Affected Left Ventricular Excessive Trabeculation Patients

open access: yesLife
Genetically determined left ventricular excessive trabeculation (LVET) has a wide clinical spectrum ranging from asymptomatic subjects to severe heart failure with arrhythmias and thromboembolic events.
Balázs Mester   +11 more
doaj   +1 more source

Statins and Exercise Training Response in Heart Failure Patients: Insights From HF-ACTION. [PDF]

open access: yes, 2016
OBJECTIVES: The aim of this study was to assess for a treatment interaction between statin use and exercise training (ET) response. BACKGROUND: Recent data suggest that statins may attenuate ET response, but limited data exist in patients with heart ...
Cooper, Lawton S.   +13 more
core   +1 more source

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