Results 31 to 40 of about 560,592 (266)

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

2014 ESC GUIDELINES ON THE DIAGNOSIS AND MANAGEMENT OF ACUTE PULMONARY EMBOLISM

Российский кардиологический журнал, 2015
The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC)Endorsed by the European Respiratory Society (ERS.
(ESC) European Society of Cardiology
doaj   +1 more source

Cholesterol Laundry of Cell Membrane and Fatty Liver by Detergent Liposomes to Improve Anti‐Cancer Drug Responsiveness of Patient Liver Tissues

Advanced Science, EarlyView.
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim, Joo Kyung Noh, Sewoom Baek, Seung Eun Yu, Jueun Kim, Seongyo Lee, Youngji Oh, Dai Hoon Han, Seyong Chung, Hak‐Joon Sung   +9 more
wiley   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

Prognostic Value of Systemic Inflammation Scores in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: A Prospective Cohort Study

Journal of Inflammation Research
Xinchen Wang,1,* Linlin Wang,1,* Yuewen Qi,2,3 Yan Liu,1 Ying Zhang,1,2,4 Ge Song,1 Qiyu Sun,3 Chen Wei,1 Jingyi Liu,1,2,4 Fei Shi,1,2,4 Lixian Sun1,2,4 1Department of Cardiology, The Affiliated Hospital of Chengde Medical University ...
Wang X, Wang L, Qi Y, Liu Y, Zhang Y, Song G, Sun Q, Wei C, Liu J, Shi F, Sun L   +10 more
doaj  

Cardiology [PDF]

Postgraduate Medical Journal, 1990
L D, Smith, D J, Coltart
openaire   +2 more sources

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source

ATP-P2X7R-NLRP3 Axis as a Unifying Mechanism of ATP-Induced Cell Death in Degenerative Bone and Cardiovascular Diseases

Journal of Inflammation Research
Jingjing Zhang,1– 3,* Linzhu Li,4,* Qianwen Guo,5 Xuesong Liu,6 Qian Qiao,1– 3 Xuerui Ye,1– 3 Hongyang Ding,1– 3 Yi Liu,7 Kaikai Wang,8 Haoling Zhang,9 Lu Cheng1– 3 1Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences, Affiliated ...
Zhang J, Li L, Guo Q, Liu X, Qiao Q, Ye X, Ding H, Liu Y, Wang K, Zhang H, Cheng L   +10 more
doaj  

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

Cardiac Function Transition in Patients with Chronic Kidney Disease Undergoing Maintenance Hemodialysis in a High-Altitude Multi-Ethnic Region: A Comparative Study Between Yi and Non-Yi Ethnic Groups

Journal of Inflammation Research
Jingjing Zhang,1– 3,* Zhaoyu Li,4,* Xueliang Xiao,5 Xuesong Liu,6 Qian Qiao,1– 3 Lu Cheng,1– 3 Jun Sha,5 Yufei Yang,7 Wangzheqi Zhang,8 Haoling Zhang,9 Xuerui Ye1– 3 1Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences, Affiliated ...
Zhang J, Li Z, Xiao X, Liu X, Qiao Q, Cheng L, Sha J, Yang Y, Zhang W, Zhang H, Ye X   +10 more
doaj