A review of multidisciplinary care in metabolic dysfunction-associated steatohepatitis and cardiometabolic disease, with a focus on Canada. [PDF]
Kim J +5 more
europepmc +1 more source
Summary Iron deficiency anaemia (IDA) is associated with adverse pregnancy outcomes globally. Women with inherited bleeding disorders are at increased risk, with scarce data on rates of IDA screening and correction during pregnancy. The impact of correction on outcomes is unclear.
Arafat Ul Alam +4 more
wiley +1 more source
A prometabolite strategy inhibits cardiometabolic disease in an ApoE-/- murine model of atherosclerosis. [PDF]
Beckman TN +17 more
europepmc +1 more source
ABSTRACT Background Guidelines outline recommended amounts of physical activity (PA), sleep and sedentary time for optimal health. Research suggests that adults with intellectual disabilities (ID) often do not meet recommendations and that engagement in healthy behaviours is impacted by those around them. The COVID‐19 pandemic amplified these concerns.
Laura C. Koch +6 more
wiley +1 more source
Cluster analysis reveals distinct inflammatory phenotypes in cardiometabolic disease. [PDF]
Bianchi J +11 more
europepmc +1 more source
The use of different types of networks, alone and in combination, for drug target identification
Current therapeutic approaches often focus on targeting clinical symptoms or peripheral phenotypes rather than the underlying molecular mechanisms, or endophenotypes, that drive diseases. While symptom‐based drugs can alleviate discomfort, they do not necessarily alter disease progression and may overlook opportunities for prevention or early ...
Paolo Parini
wiley +1 more source
Nutrient-Induced Remodeling of the Adipose-Cardiac Axis: Metabolic Flexibility, Adipokine Signaling, and Therapeutic Implications for Cardiometabolic Disease. [PDF]
Pavlović N +4 more
europepmc +1 more source
Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi +10 more
wiley +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source

