Results 251 to 260 of about 147,725 (290)

Personalisation of the Dutch combined lifestyle intervention SLIMMER improves participant retention and weight loss in people at risk for cardiometabolic disease. [PDF]

Sci Rep
Oosterman JE, Smid DJ, Kamstra RJM, de Hoogh IM, Huizing AHJ, Caspers MPM, van den Broek TJ, Kleemann R, van Empelen P, Ter Beek J, Pasman WJ, Wopereis S.   +11 more
europepmc   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Prevalence and outcomes of DKA in type 1 and type 2 DM patients treated and not treated with SGLT‐2 inhibitors

Diabetic Medicine, EarlyView.
Abstract Aim To compare the clinical characteristics, biochemical presentation, and short‐ and long‐term outcomes of DKA in hospitalized adults with T1DM and T2DM, including the impact of SGLT2 inhibitor therapy. Methods A retrospective cohort of 2283 adults (838 with T1DM; 1445 with T2DM) hospitalized with DKA between 2013 and 2023 across Clalit ...
Elena Chertok Shacham, Sireen Sharif, Rageh Tatoor, Snait Ayalon   +3 more
wiley   +1 more source

The genetics of low and high birthweight and their relationship with cardiometabolic disease. [PDF]

Diabetologia
Moen GH, Hwang LD, Brito Nunes C, Warrington NM, Evans DM.   +4 more
europepmc   +1 more source

‘There is more to life than HbA1c’: A comprehensive qualitative framework from the Hypo‐RESOLVE project evidencing the impacts of hypoglycaemia on the quality of life of adults living with type 1 or type 2 diabetes

Diabetic Medicine, EarlyView.
Abstract Aims To develop a comprehensive, in‐depth understanding of the impacts of hypoglycaemia on the quality of life of adults living with type 1 (T1D) or type 2 diabetes (T2D). Methods Thirty‐one adults with T1D or T2D who experienced hypoglycaemia participated in semi‐structured interviews.
Philip A. Powell, Sé M. Frances, Bastiaan E. de Galan, Simon Heller, Jane Speight, Myriam Rosilio, Frans Pouwer, Mari‐Anne Gall, Christopher J. Child, Rory J. McCrimmon, Ken Tait, Jill Carlton, on behalf of the Hypo‐RESOLVE Consortium   +12 more
wiley   +1 more source

The epidemiological features of and correlation between central obesity and major cardiometabolic disease clustering among middle-aged and elderly residents in Xinjiang. [PDF]

BMC Public Health
Abudusilimu M, Muyiduli X, Rejiafu S, Sulidan A, Ling C, Zhang R.   +5 more
europepmc   +1 more source

Targeting inflammation in cardiometabolic disease: Icosapent ethyl modulates monocyte‐derived macrophages isolated from patients with cardiovascular disease with or without type 2 diabetes

Diabetic Medicine, EarlyView.
Abstract Aims Despite intensive lipid‐lowering therapy, individuals with atherosclerotic cardiovascular disease (ASCVD) exhibit residual inflammatory risk, which drives recurrent cardiovascular events. This risk is amplified in type 2 diabetes mellitus (T2DM), where a pro‐inflammatory milieu accelerates atherogenesis. Monocyte‐derived macrophages (MDMs)
J. K. Ward, M. U. Shah, K. Lee, P. E. Squires, C. E. Hills   +4 more
wiley   +1 more source

Association Between Relative Fat Mass and Cardiometabolic Disease: Age-Stratified Analysis in Young and Middle-Aged Versus Older Adults. [PDF]

Rev Cardiovasc Med
Li T, Xie X, Jin Z, Nan J, Han J, Yin L.
europepmc   +1 more source