Results 271 to 280 of about 147,725 (290)
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Obesity Duration and Cardiometabolic Disease
Arteriosclerosis, Thrombosis, and Vascular Biology, 2023Cardiovascular disease risk is known to be influenced by both the severity of a risk factor and the duration of exposure (eg, LDL [low-density lipoprotein] cholesterol, tobacco smoke). However, this concept has been largely neglected within the obesity literature. While obesity severity has been closely linked with cardiometabolic diseases, the risk of
Sharnendra K. Sidhu +2 more
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Sleep Deficiency and Cardiometabolic Disease
Sleep Medicine Clinics, 2022Epidemiologic studies have demonstrated that short sleep duration is associated with an increased risk of cardio-metabolic health outcomes including cardiovascular disease mortality, coronary heart disease, type 2 diabetes mellitus, hypertension, and metabolic syndrome. Experimental sleep restriction studies have sought to explain these findings.
Roo, Killick +2 more
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Cardiometabolic Disorders in Psoriatic Disease
Current Rheumatology Reports, 2017Patients with psoriasis and psoriatic arthritis, collectively termed psoriatic disease (PsD), are at an increased risk of developing cardiovascular diseases (CVD). The purpose if this manuscript is to review recent evidence about the epidemiology and underlying mechanisms of CVD in psoriatic patients and approaches to improve the management of these ...
Curtis, Sobchak, Lihi, Eder
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MicroRNAs in Cardiometabolic Disease
Current Atherosclerosis Reports, 2011Defects in homeostatic regulation of cholesterol and fatty acids are associated with major cardiometabolic risk factors that are prevalent in type 2 diabetes and atherosclerotic cardiovascular disease. Regulatory input is found at many levels; however, recent findings have revealed pivotal roles for small non-coding RNAs (microRNAs) of the endogenous ...
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Mitochondrial Sirtuins in cardiometabolic diseases
Clinical Science, 2017Mitochondria are heterogeneous and essentially contribute to cellular functions and tissue homeostasis. Mitochondrial dysfunction compromises overall cell functioning, tissue damage, and diseases. The advances in mitochondrion biology increase our understanding of mitochondrial dynamics, bioenergetics, and redox homeostasis, and subsequently, their ...
Xiaoqiang, Tang +3 more
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Fatty liver, cardiometabolic disease and mortality
Current Opinion in Lipidology, 2020Purpose of review We discuss the findings of the most recent metanalyses on the association between nonalcoholic fatty liver disease (NAFLD), cardiometabolic disease and mortality. Recent findings Recent metanalyses have shown that NAFLD is associated with incident type 2 diabetes ...
Bedogni, G, Gastaldelli, A, Foschi, FG
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Genetic variation, adipokines, and cardiometabolic disease
Current Opinion in Pharmacology, 2020Adipokines are adipocyte-secreted cell signalling proteins that travel to distant target organs and tissues, where they regulate a variety of biological actions implicated in cardiometabolic health. In the past decade, genome-wide association studies have identified multiple genetic variants associated with circulating levels of adipokines, providing ...
Sophia Metz +2 more
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Vascular regenerative cells in cardiometabolic disease
Current Opinion in Cardiology, 2023Purpose of review This review will provide an overview of the recent literature linking the pathophysiology of cardiometabolic disease with the depletion and dysfunction of circulating vascular regenerative (VR) cell content. Moreover, we provide rationale for the use of VR cells as a biomarker for cardiovascular risk and the ...
Ehab, Bakbak +4 more
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Cardiometabolic syndrome and chronic kidney disease
Current Diabetes Reports, 2006Chronic kidney disease (CKD) is increasingly recognized as a major risk factor for end-stage renal disease (ESRD), cardiovascular (CV) disease, and CV-related premature death. More than 8 million people in the United States have CKD; therefore, preventive stratiegies should be directed at identifying risk factors for this condition.
Guido, Lastra +3 more
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