Results 101 to 110 of about 128,082 (209)

Study Protocol for a Stepped-Wedge Randomized Cookstove Intervention in Rural Honduras: Household Air Pollution and Cardiometabolic Health [PDF]

, 2019
Growing evidence links household air pollution exposure from biomass-burning cookstoves to cardiometabolic disease risk. Few randomized controlled interventions of cookstoves (biomass or otherwise) have quantitatively characterized changes in exposure ...
Africano, Sebastian, Benka-Coker, Megan L., Brook, Robert, Clark, Maggie L., Good, Nicholas, Keller, Joshua P., L\u27Orange, Christian, Nelson, Tracy L., Osorto Pinel, Anibal, Peel, Jennifer L., Quinn, Casey, Rajkumar, Sarah, Volckens, John, Walker, Ethan S., Weller, Zachary D., Young, Bonnie N.   +15 more
core   +1 more source

Pediatric Obesity: Influence on Drug Dosing and Therapeutics [PDF]

, 2018
Obesity is an ongoing global health concern and has only recently been recognized as a chronic disease of energy homeostasis and fuel partitioning. Obesity afflicts 17% of US children and adolescents.
Ameer, Barbara, PharmD, MBA, BCPS, FCP, Weintraub, Michael, MD   +1 more
core   +1 more source

Prolonged dual antiplatelet therapy in invasively treated acute coronary syndrome patients with different lipoprotein(a) concentrations

Cardiology Journal
BACKGROUND: Lipoprotein(a) [Lp(a)] was positively associated with recurrent ischemic events in patients with acute coronary syndrome (ACS). This study was performed to investigate the effect of Lp(a) levels on outcomes of dual antiplatelet therapy (DAPT)
Kongyong Cui, Shaoyu Wu, Dong Yin, Weihua Song, Hongjian Wang, Chenggang Zhu, Lei Feng, Yuejin Yang, Rui Fu, Kefei Dou   +9 more
doaj   +1 more source

Impact of drug distribution into adipose on tissue function: The cholesteryl ester transfer protein (CETP) inhibitor anacetrapib as a test case

Pharmacology Research & Perspectives, 2019
Anacetrapib is an inhibitor of cholesteryl ester transfer protein (CETP) previously under development as a lipid‐modifying agent that reduces LDL‐cholesterol and increases HDL‐cholesterol in hypercholesterolemic patients.
Douglas G. Johns, Sheng‐Ping Wang, Raymond Rosa, James Hubert, Suoyu Xu, Ying Chen, Thomas Bateman, Robert O. Blaustein   +7 more
doaj   +1 more source

Genetics of cardiometabolic disease progression

Abstract Background Genome-wide association studies have been crucial in gaining insights into the genetics of cardiometabolic diseases. However, little is known about the genetics of cardiometabolic disease progression which may have both a different genetic architecture and significant implications
Johanne M. Justesen, Guhan Venkataraman, Yosuke Tanigawa, Ruilin Li, Trevor Hastie, Robert Tibshirani, Joshua W. Knowles, Manuel A. Rivas   +7 more
openaire   +2 more sources

Association of Triglyceride Glucose-Derived Indices with Recurrent Events Following Atherosclerotic Cardiovascular Disease

Journal of Obesity & Metabolic Syndrome
Background : Triglyceride glucose (TyG) and TyG-body mass index (TyG-BMI) are reliable surrogate indices of insulin resistance and used for risk stratification and outcome prediction in patients with atherosclerotic cardiovascular disease (ASCVD).
Sha Li, Hui-Hui Liu, Yan Zhang, Meng Zhang, Hui-Wen Zhang, Cheng-Gang Zhu, Yuan-Lin Guo, Na-Qiong Wu, Rui-Xia Xu, Qian Dong, Ke-Fei Dou, Jie Qian, Jian-Jun Li   +12 more
doaj   +1 more source

Pulse pressure associates with severity and worse outcomes in patients with stable coronary artery disease

npj Cardiovascular Health
The association of pulse pressure (PP) with the severity and cardiovascular (CV) outcomes in stable coronary artery disease populations with normal ejection fraction are sparse.
Yan Zhang, Sha Li, Hui-Wen Zhang, Yuan-Lin Guo, Na-Qiong Wu, Cheng-Gang Zhu, Rui-Xia Xu, Jie Qian, Ke-Fei Dou, Jian-Jun Li   +9 more
doaj   +1 more source

Prognostic role of lipoprotein(a) in atherosclerotic cardiovascular disease risk from a perspective on current risk stratification

MedComm
Lipoprotein(a) [Lp(a)] is an emerging predictor for atherosclerotic cardiovascular disease (ASCVD) but the association from a perspective on current risk stratification was unknown.
Sha Li, Hui‐Hui Liu, Yan Zhang, Meng Zhang, Hui‐Wen Zhang, Cheng‐Gang Zhu, Na‐Qiong Wu, Rui‐Xia Xu, Qian Dong, Jie Qian, Ke‐Fei Dou, Yuan‐Lin Guo, Jian‐Jun Li   +12 more
doaj   +1 more source

Walking the VLDL tightrope in cardiometabolic diseases

Trends in Endocrinology & Metabolism
Very-low-density lipoprotein (VLDL), a triglyceride-rich lipoprotein secreted by hepatocytes, is pivotal for supplying peripheral tissues with fatty acids for energy production. As if walking on a tightrope, perturbations in the balance of VLDL metabolism contribute to cardiometabolic dysfunction, promoting pathologies such as cardiovascular disease ...
Mindy Kim, Ze Zheng
openaire   +3 more sources

The association between sleep disorders and the risk of atherosclerotic cardiovascular disease: regression analysis and neural network prediction based on NHANES data

Journal of Cardiothoracic Surgery
Background Sleep quality and duration play a critical role in cardiovascular health. In recent years, sleep disorders have been identified as potential risk factors for atherosclerotic cardiovascular disease (ASCVD).
Ling-bing Meng, Kongyong Cui, Yanjun Song, Bowen Li, Yongbao Zhang, Kefei Dou   +5 more
doaj   +1 more source