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Associations of Genetic Liability to Six Psychiatric Disorders With Cardiometabolic Diseases
Bergstedt J +22 more
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Obesity and the risk of cardiometabolic diseases
Nature Reviews Cardiology, 2023 The prevalence of obesity has reached pandemic proportions, and now approximately 25% of adults in Westernized countries have obesity. Recognized as a major health concern, obesity is associated with multiple comorbidities, particularly cardiometabolic disorders.
Pedro L Valenzuela +2 more
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Obesity Duration and Cardiometabolic Disease
Arteriosclerosis, Thrombosis, and Vascular Biology, 2023Cardiovascular disease risk is known to be influenced by both the severity of a risk factor and the duration of exposure (eg, LDL [low-density lipoprotein] cholesterol, tobacco smoke). However, this concept has been largely neglected within the obesity literature. While obesity severity has been closely linked with cardiometabolic diseases, the risk of
Sharnendra K. Sidhu +2 more
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Sleep Deficiency and Cardiometabolic Disease
Sleep Medicine Clinics, 2022Epidemiologic studies have demonstrated that short sleep duration is associated with an increased risk of cardio-metabolic health outcomes including cardiovascular disease mortality, coronary heart disease, type 2 diabetes mellitus, hypertension, and metabolic syndrome. Experimental sleep restriction studies have sought to explain these findings.
Roo, Killick +2 more
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MicroRNAs in Cardiometabolic Disease
Current Atherosclerosis Reports, 2011Defects in homeostatic regulation of cholesterol and fatty acids are associated with major cardiometabolic risk factors that are prevalent in type 2 diabetes and atherosclerotic cardiovascular disease. Regulatory input is found at many levels; however, recent findings have revealed pivotal roles for small non-coding RNAs (microRNAs) of the endogenous ...
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Cardiometabolic Disorders in Psoriatic Disease
Current Rheumatology Reports, 2017Patients with psoriasis and psoriatic arthritis, collectively termed psoriatic disease (PsD), are at an increased risk of developing cardiovascular diseases (CVD). The purpose if this manuscript is to review recent evidence about the epidemiology and underlying mechanisms of CVD in psoriatic patients and approaches to improve the management of these ...
Curtis, Sobchak, Lihi, Eder
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Mitochondrial Sirtuins in cardiometabolic diseases
Clinical Science, 2017Mitochondria are heterogeneous and essentially contribute to cellular functions and tissue homeostasis. Mitochondrial dysfunction compromises overall cell functioning, tissue damage, and diseases. The advances in mitochondrion biology increase our understanding of mitochondrial dynamics, bioenergetics, and redox homeostasis, and subsequently, their ...
Xiaoqiang, Tang +3 more
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The Cardiometabolic Syndrome and Cardiovascular Disease
Journal of the CardioMetabolic Syndrome, 2006The cardiometabolic syndrome is a prevalent metabolic disorder. Epidemiologic studies correlate the cardiometabolic syndrome with an increased risk of coronary heart disease, ischemic stroke, cardiovascular mortality, and total mortality. There is also evidence that the cardiometabolic syndrome is a risk factor for abnormalities in myocardial ...
Rachel, Ash-Bernal, Linda R, Peterson
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Role of calprotectin in cardiometabolic diseases
Cytokine & Growth Factor Reviews, 2014Calprotectin represents an interesting peptide known to be involved in the pathophysiology of various inflammatory processes. Being secreted from activated neutrophils and monocytes under various conditions, it can also be found in the extracellular fluids and serve as a biomarker of ongoing inflammation, which property is currently used in the ...
Peter, Kruzliak +3 more
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