Results 1 to 10 of about 83,445 (250)

Mesenchymal Stem Cell-Derived Extracellular Vesicles as Non-Coding RNA Therapeutic Vehicles in Autoimmune Diseases

open access: yesPharmaceutics, 2022
Autoimmune diseases (ADs) are characterized by the activation of the immune system against self-antigens. More common in women than in men and with an early onset, their incidence is increasing worldwide, and this, combined with their chronic nature, is ...
Olga Martinez-Arroyo   +3 more
doaj   +1 more source

Rab3A/Rab27A System Silencing Ameliorates High Glucose-Induced Injury in Podocytes

open access: yesBiology, 2023
Diabetic nephropathy is a major complication in diabetic patients. Podocytes undergo loss and detachment from the basal membrane. Intra- and intercellular communication through exosomes are key processes for maintaining function, and the Rab3A/Rab27A ...
Olga Martinez-Arroyo   +5 more
doaj   +1 more source

Cardiometabolic Disease Risk in Normal Weight Obesity and Exercise Interventions for Proactive Prevention [PDF]

open access: yes운동과학, 2022
PURPOSE Normal weight obesity (NWO) is characterized by a normal body mass index but a high body fat mass percentage and low skeletal muscle mass, thereby increasing the risk of cardiometabolic dysfunction and morbidity.
Minje Ji, Chaeeun Cho, Sewon Lee
doaj   +1 more source

Gestational and childhood exposure to per- and polyfluoroalkyl substances and cardiometabolic risk at age 12 years

open access: yesEnvironment International, 2021
Background: Per- and polyfluoroalkyl substances (PFAS) may adversely influence cardiometabolic risk. However, few studies have examined if the timing of early life PFAS exposure modifies their relation to cardiometabolic risk.
Nan Li   +11 more
doaj   +1 more source

Optimization of small RNA library preparation protocol from human urinary exosomes

open access: yesJournal of Translational Medicine, 2020
Background Sequencing of miRNAs isolated from exosomes has great potential to identify novel disease biomarkers, but exosomes have low amount of RNA, hindering adequate analysis and quantification.
Dolores Olivares   +5 more
doaj   +1 more source

Health disparities in cardiometabolic risk among Black and Hispanic youth in the United States

open access: yesAmerican Journal of Preventive Cardiology, 2021
Cardiometabolic risk factors in children and adolescents track into adulthood and are associated with increased risk of atherosclerotic cardiovascular disease.
Sophia Figueroa Katz   +2 more
doaj   +1 more source

Exosomes as Drug Delivery Systems: Endogenous Nanovehicles for Treatment of Systemic Lupus Erythematosus

open access: yesPharmaceutics, 2020
Exosomes, nanometer-sized lipid-bilayer-enclosed extracellular vesicles (EVs), have attracted increasing attention due to their inherent ability to shuttle proteins, lipids and genes between cells and their natural affinity to target cells.
Ana Ortega   +3 more
doaj   +1 more source

Lifestyle Behaviors and Cardiometabolic Diseases by Race and Ethnicity and Social Risk Factors Among US Young Adults, 2011 to 2018

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Cardiometabolic health has been worsening among young adults, but the prevalence of lifestyle risk factors and cardiometabolic diseases is unclear.
Shuxiao Shi   +4 more
doaj   +1 more source

Healthier Lifestyles Attenuated Association of Single or Mixture Exposure to Air Pollutants with Cardiometabolic Risk in Rural Chinese Adults

open access: yesToxics, 2022
There is little research on how long-term exposure to independent and multiple air pollutants changes cardiometabolic risk in adults. In addition, previous studies focused on only the effect of one or two lifestyles on cardiometabolic risk.
Xueyan Wu   +11 more
doaj   +1 more source

Urinary exosome miR-146a is a potential marker of albuminuria in essential hypertension

open access: yesJournal of Translational Medicine, 2018
Background There is increasing interest in using extracellular vesicle-derived microRNAs (miRNAs) as biomarkers in renal dysfunction and injury. Preliminary evidence indicates that miRNAs regulate the progression of glomerular disease.
Javier Perez-Hernandez   +8 more
doaj   +1 more source

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