Results 151 to 160 of about 83,445 (250)

Obesity and cardiometabolic risk

, 2007
Adipose tissue releases a number of biologically active molecules that are thought to have a causative role in the pathogenesis of insulin resistance and vascular disease. Serum free fatty acids (FFAs) are generated by lipolysis (breakdown of stored triglycerides).
openaire   +1 more source

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source

Prevalence and interrelationships of cardiometabolic risk factors in Polish adults. [PDF]

Sci Rep
Matłosz P, Wyszyńska J, Asif M, Nalborczyk P.   +3 more
europepmc   +1 more source

Chinese Expert Consensus on the Use of Ultrasound‐Derived Fat Fraction in the Assessment of Metabolic Dysfunction‐Associated Steatotic Liver Disease (2025 Edition)

Portal Hypertension &Cirrhosis, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has become one of the leading causes of chronic liver diseases in China and even globally. Early non‐invasive diagnosis and grading MASLD, along with timely intervention, are crucial for assessing the disease condition and slowing the disease progression.
Liyun Xue, Yuli Zhu, Huixiong Xu, Hong Ding   +3 more
wiley   +1 more source

Hyperuricaemia and cardiometabolic risk

Indian Heart Journal, 2018
Ramesh Ratanlal Dargad, Mahesh Ramshabd Munakka Prajapati   +1 more
openaire   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

Endocrine and metabolic determinants of cardiometabolic risk in mild autonomous cortisol secretion. [PDF]

EBioMedicine
Prete A, Abdi L, Canducci M, van den Brandhof EL, Albors-Zumel A, Jenkinson C, Gilligan LC, Zhang Y, Visser L, Chortis V, Najdekr L, Jankevics A, Lloyd GR, Winder CL, Tsagarakis S, Lang K, Macech M, Fell V, Vodanovic ID, Reimondo G, Marina LV, Deutschbein T, Balomenaki M, O'Reilly MW, Bednarczuk T, Dusek T, Diamantopoulos A, Asia M, Kondracka A, Yu K, Masjkur JR, Quinkler M, Ueland GÅ, Dennedy MC, Beuschlein F, Tabarin A, Fassnacht M, Ivovic M, Terzolo M, Kastelan D, Young WF, Manolopoulos KN, Ambroziak U, Vassiliadi DA, Bancos I, Sitch AJ, Taylor AE, Tino P, Biehl M, Dunn WB, Arlt W, ENSAT EURINE-ACT Investigators.   +51 more
europepmc   +1 more source

Obstructive sleep apnea and cardiovascular disease in individuals with metabolic dysfunction‐associated fatty liver disease: A prospective cohort study

Sleep Research, EarlyView.
Abstract Objective To assess the association between obstructive sleep apnea (OSA) risk levels and major cardiovascular disease (CVD) subtypes in individuals with metabolic dysfunction‐associated fatty liver disease (MAFLD). Methods This cohort study included 128,022 MAFLD participants from the UK Biobank without CVD at baseline.
Haizhen Chen, Ying Zheng, Hanzhang Wu, Ningjian Wang, Xiao Tan   +4 more
wiley   +1 more source

Distinct Gut Microbiome Profiles Underlying Cardiometabolic Risk Phenotypes in Individuals with Obesity. [PDF]

Nutrients
Nedeva I, Assyov Y, Duleva V, Karamfilova V, Kamenov Z, Naydenov J, Handjieva-Darlenska T, Denchev V, Kolevski A, Pencheva V, Vodenicharov V.   +10 more
europepmc   +1 more source

Bile acid metabolism and sleep: Mechanistic interplay and clinical implications of the gut–liver–brain axis

Sleep Research, EarlyView.
Abstract The bidirectional interplay between sleep and metabolic homeostasis is fundamental to physiological health. While the roles of glucose and lipid metabolism in sleep regulation have been extensively characterized, bile acids (BAs), which are traditionally viewed as digestive surfactants, are emerging as critical metabolic messengers with ...
Yu Jiang, Shuangyan Li, Dhirendra Paudel, Miaoqin Tan, Bin Zhang   +4 more
wiley   +1 more source