Results 161 to 170 of about 83,445 (250)

Innovative γ‐Oryzanol and KC2 Based Lipid Nanoparticles: OryKL Platform Provides Safe and Efficient In Vivo mRNA Delivery

Small, EarlyView.
Identified through multi‐stage selection process, a formulation combining γ‐oryzanol and DLin‐KC2‐DMA, termed as OryKL, demonstrates unique nano‐structural features, highly efficient mRNA transfection and functional integrity during long‐term storage, enables broad biodistribution and distinct cell tropism following intravenous administration with no ...
Pengkai Shi, Haikun Liu, Ahmed Refaat, Hung Nguyen, Anne Nguyen, Kaiting Miao, Yuyang Song, Sylvain Trépout, Rico F. Tabor, Liliana de Campo, Karlheinz Peter, Mark Louis P. Vidallon, Xiaowei Wang   +12 more
wiley   +1 more source

Identification of modifiable plasma protein markers of cardiometabolic risk in children and adolescents with obesity. [PDF]

Nat Commun
Stinson SE, Huang Y, Thielemann R, Stankevic E, Lund MAV, Holm LA, Fonvig CE, Juel HB, Borisevich D, Thiele M, Krag A, Ängquist L, Sørensen TIA, Pedersen O, Christiansen M, Holm JC, Hansen T.   +16 more
europepmc   +1 more source

General and central obesities were associated with increased risk of inflammatory bowel disease: A large‐scale prospective cohort study

VIEW, EarlyView.
Prior evidence suggested inconsistent findings in terms of the relationship between obesity and inflammatory bowel disease (IBD) occurrence. We demonstrated that both general and central obesities were associated with an increased risk of developing IBD, ulcerative colitis, and Crohn's disease in a large‐scale prospective cohort.
Qian Zhang, Yijun Chen, Shuang Yu, Si Liu, Shutian Zhang, Shanshan Wu   +5 more
wiley   +1 more source

Physical activity and sedentary pattern compositions and cardiometabolic risk in preschoolers. [PDF]

J Act Sedentary Sleep Behav
Downing KL, Verswijveren SJJM, Bell L, Vuillermin P, Burgner D, Ponsonby AL, O'Hely M, Timperio A, Salmon J, Hesketh KD.   +9 more
europepmc   +1 more source

What Happens After Menopause (WHAM)? A Progress Report of a Prospective Controlled Study of Women After Pre‐Menopausal Risk‐Reducing Bilateral Salpingo‐Oophorectomy

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Surgical menopause, the removal of both ovaries prior to natural menopause, may impact short‐and long‐term physical and emotional health. An increasingly common cause of surgical menopause is risk‐reducing salpingo‐oophorectomy (RRSO) in those at high inherited risk of ovarian cancer.
Sarah A. L. Price, Pauline M. Maki, Samar R. El Khoudary, Alison Brand, Rakibul M. Islam, Susan M. Domchek, Hadine Joffe, Gita D. Mishra, Katrina M. Moss, Fiona C. Baker, Sabine Braat, John D. Wark, Martha Hickey   +12 more
wiley   +1 more source

Cardiometabolic Risk Factors Among Adults in a Rural Amazonian Peruvian Population. [PDF]

Medicina (Kaunas)
Arce-Huamani MA, Caceres-Cuellar GA, Guevara-Paz AY, Lopez-Quispe CR, Barzola-Blancas AK, Cespedes-Atto VA, Acosta-Celis CG, Pérez-Acuña K, Carrascal-Astola W, Torres-Roman JS.   +9 more
europepmc   +1 more source

Eating Speed and Its Associations with Cardiometabolic Risk Factors in Children. [PDF]

Children (Basel)
Gómez-Martínez MA, Rodríguez-Vera D, Mendoza GO, Lastiri FL, Morales-González JA, Pinto-Almazán R, Vergara-Castañeda A.   +6 more
europepmc   +1 more source

The Economic Burden of Gestational Diabetes and Body Mass Index Changes Between Pregnancies: A Retrospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To determine associations between gestational diabetes mellitus (GDM) and body mass index (BMI) change between consecutive pregnancies, and hospital length of stay (LOS) and hospital costs. Design Retrospective cohort study. Setting Two maternity hospitals, New South Wales, Australia.
Rashidul Alam Mahumud, Glynis Pauline Ross, Adam Mackie, Rachael L. Morton, Kirsten I. Black   +4 more
wiley   +1 more source

Gaps in Current Cardiometabolic Risk Assessment: A Review Supporting the Development of the C.O.R.E. Indicator Model. [PDF]

J Clin Med
Geraci C, Geraci G, Buonauro A, Morello V, La Rocca F, Esposito R.   +5 more
europepmc   +1 more source

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong, Sarah Hillman, Sharon Dixon, Anupa Shah, Radha Venkatakrishnan, Jeremy W. Tomlinson   +5 more
wiley   +1 more source